Sabir Shaikh*1, Amol Shete2, Rajendra Doijad3
1S. Kant Health care R&D Centre,
Turbhe, Navi Mumbai, Maharashtra-400705.
2Department of pharmaceutics,
Krishna institute of Pharmacy
Krishna institute medical sciences Deemed university, Karad. MS, India
3Department of Pharmaceutics and Quality Assurance,
Shree Santkrupa College of Pharmacy Ghogaon, Karad, MS, India
The objectives of present investigation were to formulate and evaluate herbal gel for mouth ulcer treatment of dried powdered guava leaves.
Herbal gel was prepared by using different concentration of powdered guava leaves and Carbopol 934, Propylene glycol as a gel base. Formulations were evaluated for various parameters
Infrared spectroscopy revealed that there was no interaction between powdered Guava leaves and Polymer. The formulated gel was transparent, homogeneous and pH ranges from 7 to 7.5. Formulation showed acceptable rheological behaviour with applicable Spreadability and Extrudability properties. Anti-fungal studies of formulations showed excellent efficacy against Aspargiliousaureus, Candida albicans.
From the experimental evidence of invitro studies it was observed that powdered guava leaves contain flavonoids so it showed significant antioxidant effect.
Developed herbal formulation was stable, safe and effective over to synthetic formulations for the treatment of mouth ulcer.