Orodispersible liquisolid compacts: A novel approach to enhance solubility and bioavailability

  • Posted on: 30 May 2018
  • By: admin

 

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June 2018 ARTICLE LIST >>

PharmaTutor (June - 2018)

 

ISSN: 2347 - 7881
(Volume 6, Issue 6)

 

Received On: 18/04/2018; Accepted On: 17/05/2018; Published On: 01/06/2018

 

AUTHORS:
Vinoth Kumar P1, Rajalakshmi AN 1*, Stephen P 2
1 Department of Pharmaceutics, College Of Pharmacy,
Mother Theresa Postgraduate and Research Institute of Health Sciences,
Puducherry, India
2 Formulation Research and Development,
SaiMirra Innopharm Pvt Ltd., Chennai, Tamil Nadu, India
*ocusertraji@gmail.com

 

 

ABSTRACT
Orodispersible liquisolid system is the combination of liquisolid technique and orodispersible system. The poor dissolution rate of water insoluble drug is a major drawback for the development of pharmaceutical dosage forms. The oral absorption of drug is most often controlled by dissolution in the gastrointestinal tract. Liquisolid system has been used to enhance dissolution rate of poorly water-soluble drugs. Orodispersible tablets are given in order to provide fast action by disperse in the mouth, without the need of water and make them compliance for paediatric and geriatric patients and to bypass the liver metabolism.

 

 

How to cite this article: Vinoth P, Rajalakshmi AN, Stephen P; Orodispersible liquisolid compacts: A novel approach to enhance solubility and bioavailability; PharmaTutor; 2018; 6(6); 28-35; http://dx.doi.org/10.29161/PT.v6.i6.2018.28

 

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