Articles

INVITRO STUDIES ON THE EFFECT OF TERMINALIA ARJUNA IN ADIPOCYTE 3T3 - L1 CELL LINES

ABOUT AUTHORS
1Ranjitha B, 2Dinesh Bhaskar, *3Balasubramanian Sathyamurthy
1, 2Department of Biochemistry, Reva Institute of Science and Management, Bangalore – 560064.
3Professor, Department of Biochemistry, Ramaiah College of Arts, Science and Commerce, Bangalore – 560054

ABSTRACT: 
The leaves of Terminalia Arjuna are commonly known as Arjuna. It is used as traditional medicinal plant distributed throughout the greater part of the Indian Peninsula along rivers and found in Sub-Himalayan tract, Chota Nagpur, Orissa, West Bengal, Punjab, Deccan and Konkan it has many medicinal properties like anti bacteria, anti inflammatory and used for the treatment of Asthama, Bronchities. These leaf extracts are found to have antioxidant, anticancer and antidiabetic activities. Out of many constituents arjunolic acid is the active principle which is responsible for antidiabetic effects. The present work was aimed to study the effect of Terminalia arjuna. Methanolic extracts on adipocyte 3T3-L1cell line and found the phytochemical compounds of Terminalia arjunaleaves have more inhibitory scavenging and more antidiabetic activities

NUTRACEUTICAL: A NEW SCOPE AND OPPORTUNITY OF HEALTHCARE

ABOUT AUTHORS
Abhishek Kumar*, Sandhya Singh, Rajesh Kumar, Pankaj Maurya, Devendra Nath
Department of Pharmacy
Ashoka Institute of Technology and Management,
Varanasi, U.P., India

ABSTRACT
Nutraceutical from Nutrition and Pharmaceutical, in 1989. Nutraceuticals refers to foods having a medicinal effect on health of human beings. It consist of food supplements, herbal products, probiotics and prebiotics, medical foods meant for prevention and treatment of diseases. Major nutraceuticals posses multiple therapeutic effect with lacking of unwanted effects. A nutraceutical is demonstrated to have a physiological benefit or provide protection against chronic disease. I try to redefine functional foods and nutraceuticals. When food is being cooked or prepared using scientific intelligence with or without knowledge is called functional food. Thus, functional food provides the body with the required amount of vitamins, fats, proteins, carbohydrates, etc, needed for its healthy survival When functional food aids in the prevention, treatment of disease(s) and disorder(s) other than anemia, it is called a nutraceutical. Nutraceuticals are non toxic food components which claimed to possess multiple therapeutic benefits. Some popular nutraceuticals include glucosamine, ginseng, echinacea, folic acid, cod liver oil, omega-3 fatty acid(MUFA,PUFA), calcium-enriched orange juice, green tea, plant phenols etc.

ASSESSING THE DIMENSIONS OF HOSPITAL RECORDS (MEDICAL RECORDS) IN DELIVERING QUALITY OF SERVICE TO PATIENTS

ABOUT AUTHORS
Kenneth Amoah-Binfoh1, Collins Marfo Agyeman2, Pradhyuman Singh Lakhawat1
1 Dept. of Business Studies,
SHUATS University, Allahabad, U.P, India.
2 Dept. of Business,
All Nations University, Koforidua, Ghana.

ABSTRACT
Medical records through which hospital statistics are generated serve as eyes and ears to the hospital administrator. Medical records are of importance to the hospital for evaluation of its services for better patients care. Failure of duty towards the patient is failure to maintain proper medical records. Recently, medical records have become very importance in the area of education and training of physicians and others being the basis for clinical research. Medical records make research effective and require scientific observational records. Medical records as perceived to be the instructions documented in a patients file serve as a means of communication between the physicians and other health professionals caring for the patient. The essence of medical record is to ensure continuity of care. Ensuring continuity of care means medical records must be comprehensive, planned, economical, time-honored and classified in a right way. Managing these records are found concerned with several types of problems. The record keeping, making use of the records, destroying the old records of no use; documenting the important records found useful to the researchers and the medical scientists. The objectives of this paper were to find the challenging dimensions of medical records in delivering quality of service to patients and to identify the significant role of medical records in delivering quality service to patients. The researchers employed systematic sampling with a population of about 123 which included nurses, medical records and admission office (clinic-administrative departments) with a desired sample size of 60. It was found that creating as one of the dimensions of medical record was very difficult to do. It was recommended that indexing or cataloguing should be more innovative and simple within time limit, so that the required papers or records are easily made available to the concerned person.

GREEN TEA –AN ANTIOXIDANT MYSTIC HERB

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ABOUT AUTHORS
SUNIL JAIN*, HARVINDER POPLI, GEETA AGGARWAL, MADHU GUPTA
Dept. of Pharmaceutics, School of Pharmaceutical Sciences
Delhi Pharmaceutical Sciences and Research University,
New Delhi -110017

ABSTRACT
It is worldwide accepted that green tea have supernatural property to fight against chronic diseases such as cancer and many more. The presence of polyphenols in green tea is having such property to protect against severe disease and have antioxidant potential. The purpose of this review to explore the beneficial antioxidant potential of green tea with compilation of previously published literature. Green tea is produced from the leaves of the Camellia sinensis plant has provided to be the most popular beverages worldwide. Now people from 160 countries in the world are accustomed to tea drinking although the amount of green tea consumption in worldwide is less than other tea and coffee. Generally, green tea has been found to be superior to black tea in terms of health benefits due to their greater health benefits their demands and popularities are enhanced. The processes used in the manufacture of black tea are known to decrease levels of the monometric catechins to a much greater extent than the less severe conditions applied to other teas. Green tea is accounted for to contain a large number of bioactive fixings which are nearly contributed by polyphenols which assumes a key part of counteractive action and treatment of numerous infections and diseases. The major polyphenols in green tea are catechins, epicatechin (EC), epigallocatechin (EGC), epicatechin gallate (ECG) and epigallocatechin gallate (EGCG). Epigallocatechin gallate is viewed as the most significant active component. This review highlights chapter will highlight the antioxidant activities of green tea that is connected with the high cell reinforcement parts of green tea. This article shows the advantages of green tea for its calming, cancer prevention agent potential and oral human services. Despite the fact that the human clinical information is as yet constrained, this article demonstrates that green tea has its place in both the traditional and elective medicinal groups.

A REVIEW ON NOVEL APPROACHES FOR COLON TARGETED DRUG DELIVERY SYSTEMS

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ABOUT AUTHORS
Sumedha Saxena, Chandan Kumar Singh*, MukeshYadav, Alex Laurel Samson.
Department of Pharmacy, Dr. M.C. Saxena College of pharmacy, Lucknow, (U.P.)
*chandansingh.skic@gmail.com

ABSTRACT
This review mainly focus on targeted drug delivery to the colon is extremely desirable for local treatment of inflammatory bowel disease such as ulcerative colitis, crohn's disease, amoebiasis, colonic cancer as well as for systemic delivery of protein and peptide drugs. The colon is a site where local delivery allows topical treatment of inflammatory bowel disease and systemic delivery of drug can take place. Treatment of colon can be made effective if the drug can be targeted directly into the colon because drug release and absorption should not be take in abdomen and the small intestine and bioactive agents should not be degraded and to allow drug release into the colon. Drug targeting to the colonic area is not only associated with the treatment of colonic ailment locally but also delivering drugs such as protein and peptide for their systemic effects which are degraded and bioavailability is very depressed due to the instability in the GI Tract.

ANTI-ANEMIC ACTIVITY OF HYDRO-ALCOHOLIC EXTRACT SEEDS OF FOENICULUM VULGARE IN PHENYLHYDRAZINE INDUCED ANEMIC RATS

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ABOUT AUTHORS
CHANDRAKANTA KUSHWAH 1*, DEEPANSHU GUPTA 1, ANKUR JOSHI 1, SAPNA MALVIYA 1 & ANIL KHARIA 1
1 Department of pharmacy Modern institute of Pharmaceutical Sciences,
Indore (M.P.), India
chandakushwah0@gmail.com

ABSTRACT
The main objective of this research was to evaluate the anti-anemic activity in hydro-alcoholic extract of seeds of Foeniculum vulgare in phenylhydrazine induced anemic rats. Phenylhydrazine (60mg/kg) was given intraperitoneally in rats for two days to induce anemia. The animal were divided into 5 groups of 6 animal each. Group 1 was known as normal control group, Group 2 was known as anemic control group, Group 3 was known as standard reference control group given with Vit. B12, Group 4 was known as test control-I given with 100mg/kg of hydro-alcoholic extract of seeds of Foeniculum vulgare, Group 5 was known as test control-II given with 200mg/kg of hydro-alcoholic extract of seeds of Foeniculum vulgare. All the test drugs were given for 28 days through oral route once in a day. On 29th day blood was taken out through tail puncture and was subjected to the determination of RBC, Hb and percentage Haematocrit. Both the hydro-alcoholic seeds extract of Foeniculum vulgare and Vit. B12 significantly increase the HB, RBC & percentage Haematocrit level which shows that Foeniculum vulgare seeds exhibits the anti-anemic activity

FORMULATION AND CHARACTERIZATION OF HERBAL LIPSTICK USING COLORED PIGMENT OF PUNICA GRANATUM

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ABOUT AUTHORS
Megha Padiyar1, *Sourabh D Jain1, Deepak Birla1, Jayanti Mukherjee1, Vimukta Sharma2
1Shri Bherulal Pharmacy Institute, Indore (M.P.), India
2BM College of Pharmaceutical Education and Research, Indore (M.P.), India
*sourabhjain072@gmail.com

ABSTRACT:
Herbal Cosmetics are in rising demand in the world market as these are the priceless gift of nature with enhanced activity and lesser or no side effects. The concept of beauty and use of natural cosmetics is as primordial as mankind and civilization. Herbal cosmetics as the name suggests are natural and free from all the destructive artificial chemicals. The present work was aimed to formulate herbal lipstick by using various natural ingredients like concentrated juice of pomegranate seeds (Punica granatum), shikakai, dried ginger powder, lemon juice, coconut oil, bees wax, paraffin wax, strawberry essence, vanilla essence and so on. The formulated herbal lipstick was evaluated and various parameters such as color, melting point, breaking point, force of application, surface anomalies, pH, skin irritation test and aging stability were determined and reported herewith.

ANTI-ANEMIC ACTIVITY OF HYDRO-ALCOHOLIC EXTRACT OF FRUIT OF ALLIUM TRICOCCUM IN PHENYLHYDRAZINE INDUCED ANEMIC RATS

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PhotoABOUT AUTHORS
DEEPANSHU GUPTA *, CHANDRAKANTA KUSHWAH , ANKUR JOSHI , SAPNA MALVIYA & ANIL KHARIA
Department of pharmacy
Modern institute of Pharmaceutical Sciences, (Shri Prabhat Chandra Kharia Research and Educational Society)
Indore, M.P, India
*guptadeepanshu252@gmail.com

ABSTRACT
This current research was done to bring out the anti-anemic activity in hydro-alcoholic extract of fruit of Allium tricoccum in phenylhydrazine induced anemic rats. The anemia was induced by the administration of Phenylhydrazine (60mg/kg) intraperitoneally in rats for two days. The animals were divided into 5 groups containing 6 animals each. 1st group was served as normal control group, 2nd group was served as anemic control, 3rd group was served as standard reference control administered with Vit. B12 complex, 4th group was served as test control-I administered with 100mg/kg of hydro-alcoholic extract of fruit of Allium tricoccum and 5th group was served as test control-II administered with 200mg/kg of hydro-alcoholic extract of fruit of Allium tricoccum. All the test drugs were given for 28 days daily through oral route. On 29th day blood was withdrawn, through tail puncture and subjected to the estimation of RBC, Hb and percentage Haematocrit. Both the hydro-alcoholic fruit extract of Allium tricoccum and Vit. B12 significantly increase the Haemoglobin, Red Blood Cells & percentage Haematocrit level which conclude that Allium tricoccum fruit exhibits’ the anti-anemic activity.

ADVANCED TECHNOLOGY ON ACCURACY IN DETECTION OF BREAST CANCER

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ABOUT AUTHORS
SUJATHA RAMASAMY 1*, SRIKANTA PRIYADARSHAN PATRA 1,PULAK RANJAN BASAK 1,
1Technology Information, Forecasting and Assessment Council (TIFAC)-DST, New Delhi, India.
*sujathar23@gmail.com

ABSTRACT:
Breast cancer is one of the leading type of cancer in India. Current methods used in detection of cancer like mammography combined with Digital Infrared Imaging can help learn about  earlier stages of cancer with accuracy.The Niramai an Indian startup developed a software with machine learning and artificial intelligence which can detect and sense cancer cells that are 5 times smaller than what has been done presently. The method is non-contact, painless and free of radiation. This method can help detection of cancer in very early stage before showing any suspicious or alarming signs.

ORODISPERSIBLE LIQUISOLID COMPACTS: A NOVEL APPROACH TO ENHANCE SOLUBILITY AND BIOAVAILABILITY

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ABOUT AUTHORS
VINOTH KUMAR P 1, *RAJALAKSHMI A.N.1, STEPHEN P2
1Department of Pharmaceutics, College Oof Pharmacy, Mother Theresa Postgraduate And Research Institute of Health Sciences, Puducherry-6, India
1 Department of Pharmaceutics, College of Pharmacy, Mother Theresa Postgraduate And Research Institute of Health Sciences, Puducherry-6, India
2 Formulation Research and Development, Sai Mirra Innopharm Pvt Ltd., Chennai, India
*ocusertraji@gmail.com

ABSTRACT:
Orodispersible liquisolid system is the combination of liquisolid technique and orodispersible system. The poor dissolution rate of water insoluble drug is a major drawback for the development of pharmaceutical dosage forms. The oral absorption of drug is most often controlled by dissolution in the gastrointestinal tract. Liquisolid system has been used to enhance dissolution rate of poorly water-soluble drugs. Orodispersible tablets are given in order to provide fast action by disperse in the mouth, without the need of water and make them compliance for paediatric and geriatric patients and to bypass the liver metabolism.

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