FIND OUT GPAT PAPER - 2018, with key answers

Pharma Admission

pharma admission

 

1. A technique of using very small metal particles coated with desired DNA in the gene transfer is called:-
(a) Microinjection (b) Biolistic (c) Liposome mediated (d) Electroporation

2. Arrange the following steps in sequence of their order for production of recombinant Insulin:-
A. Fusion of A and B chains for disulphide bond.
B. Cynogen bromide treatment to remove methi onine and â galactosidase.
C. Introduction of A and B chain in the plasmid containing â galactosidase g ene.
D. Synthesis of A and B chain in E coli.

3. Motif is represented by:-
(a) Commas repeated on the lattice (b) 3D translational periodic arrangement of points
(c) Geometric shapes of lattice (d) Centre of symmetry in lattice

4. Statement 1 : Vortex formation can be minimized by push pull mechanism.
Statement 2 : Vortex formation reduces the mixing intensity by increasing the velocity of impeller.

(a) True, False (b) True, True (c) False, False (d) False, True

5. Which of the following fluid can be considered as an ideal fluid?
(a) Viscous fluid (b) Non-viscous fluid (c) Compressible fluid (d) All of these

6. Which of the following agencies is not classified as an ‘executive agency’ for administration of the act under the provision of Drugs and Cosmetics Act 1940?
(a) Licensing authority
(b) Drug inspectors
(c) Drugs Consultative Committee
(d) Customs collectors

7. As per Factories Act 1948, in CHAPTER VI dealing with working hours of adults, no adult worker shall be required or allowed to work in a factory for more than _______________ hours in a week.
(a) 30 (b) 40 (c) 48 (d) 56

8. Henri Fayol’s principle “Espirit de corps” means:-
(a) Corporate objective (b) Group objective (c) Team activity (d) Team spirit

9. How customer’s bias about the product will influence the marketing communication?
(a) Positive effect (b) Negative effect (c) No effect (d) Both positive and Negative

10. Which of the following is not patentable in India as per The Patents Act 1970?
(a) New product
(b) New process
(c) New use of existing drug
(d) New process for existing drug

11. Match the following enzymes in Column I with their respective functions under Column II

Column I & Column II
i. DNA ligase (p) Synthe size a DNA copy of RNA
ii. Alkaline phosphatase (q) Forms a bond between 3’ –OH and 5’-PO4
iii. Reverse transcriptase (r) Removes terminal PO4 from 3’ or 5’end of DNA
iv. Polynucleotide kinase (s) Adds phosphate to 5’ –OH end
(a) i-r, ii-s, iii-p, iv-q (b) i-p, ii-q, iii-r, iv-s (c) i-q, ii-r, iii-p, iv-s (d) i-s, ii-p, iii-q, iv-r

12. Which of the following replacement of amino acid in a protein may produce greatest change in its conformation?
(a) Ser ------->Thr (b) Glu ------->Val   (c) Gln ------->Tyr  (d) Phe -------> Ile

13. The hexose monophosphate pathway produces distinctively two useful products. Identify these products with the ratio in which they are produced.
(a) One NADPH to two ribose-6-phosphate (b) Two NADPH to one ribose-5-phosphate
(c) Two NADPH to one ribulose-5-phosphate (d) Two NADPH to one fructose-6-phosphate

14. The correct statement about Vitamin D is:-
(a) The oral administration of 1, 25-dihydoxycholecalciferol is required in chronic renal failure
(b) 25-Hydroxycholecalciferol is the active form of the vitamin
(c) Vitamin D antagonizes the effects of parathyroid hormone
(d) A deficiency of vitamin D causes an increase in calcitonin secretion

15. All of the following enzymes are used in ELISA except:-
(a) Glucose oxidase (b) Alkaline phosphatase (c) Coagulase (d) β-galactosidase

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