GPAT 2014 | Question paper with key solutions

Pharma Admission

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FIND 1-75 Questions

76-125 questions are available below:

76. Mechanism of action of Ketoconazole is:
(a) Inhibits Ergosterol synthesis
(b) Inhibits DNA gyrase
(c) Inhibits dihydropteroate synthetase
(d) Induces translation misreading

77. All are adrenal gland over activity disorders EXCEPT
(a) Addison’s disease
(b) Conn’s syndrome
(c) Cushing’s syndrome
(d) Cushing’s disease

78. The oil used in a parenteral product cannot contain.......................
(a) WFI (b) Parffin oil (c) Peanut oil (d) Glycerine

79. Identity the non-absorbable sature
(a) Catgut suture (b) Chromic catgut suture (c) Silk suture (d) Polydioxanone suture

80. The relative lowering of vapour pressure is given by
(a) Raoult’s law (b) Henry’s law (c) Boyle’s law (d) Charles law

81. Identity the functional group present in meprobamate
(a) Amide (b) Ester (c) Carbamic (d) Lactam

82. Match the following

(a) P-1, Q-2, R-4, S-3
(b) P-3, Q-4, R-1, S-2
(c) P-4, Q-3, R-1, S-2
(d) P-2, Q-4, R-1, S-3

83. Tinea capitis is ringworm infection of
(a) Feet (b) Groin (c) Head (d) Nails

84. Rank the following compounds is order of increasing reactivity in electrophilic aromatic Substitution reactions
(a) Q<P<R (b) R<P<Q (c) Q<R<P (d) P<Q<R

85. Dose dumping may be a general problem in the formulation of:
(a) Soft gelatin capsules (b) Suppositories (c) Modified release drug products (d) None

86. Codeine differ in structure from morphine by:
(a) N-methyl group (b) Acetyl group at C1 and C6 (c) –OC2H5 group (d) –OCH3 group

87. Isotopes differ in:
(a) The number of protons (b) The valency number
(c) The chemical activity (d) The number of neutrons

88. Arrange the given acids in increasing order as per the number of carbons present in them
(P) Capric (Q) Caprylic (R) Caproic (D) Lauric
(a) P<Q<R<S
(b) R<Q<P<S
(c) R<Q<P<S
(d) Q<P<R<S

89. E1cb (Elimination reaction via conjugate base) which reaction intermediate will form?
(a) Carbocation (b) Carbanion (c) Free radical (d) All

90. What are the three basic steps of conventional PCR
(a) Denature, anneal, & Strand displacement (b) Denature, anneal & extension
(c) Strand displacement, synthesis & release (d) Reverse-Transcription, anneal & extend

FIND 1-75 Questions



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