Bathinda

BREAKTHROUGHS IN EPIGENETICS

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ABOUT AUTHORS:
Shashi Shekhar Anand, Navgeet, Balraj Singh Gill*
Centre for Biosciences,
School of Basic and Applied Sciences,
Central University of Punjab, Bathinda, India
gillsinghbalraj@gmail.com

ABSTRACT
The word ‘epigenetic’ was first coined by Conrad Waddington in 1946. It deals with functionally relevant modifications to the genome that do not include a change in the nucleotide sequence. Till date observation has focused on the functions of genome sequences and how their regulation occurs. The emerging epigenetic changes and the interactions between cis-acting elements with protein factors  plays a central role in gene regulation as well as give insight to various diseases. To evaluate the crosstalk of DNA and protein by taking account of the whole genome, one new evolving technique which is called as ChIP-chip, works on the principle of combining chromatin immunoprecipitation with microarray. ChIP-chip has been recently used in basic biological studies and may be improved further and can be useful for other to aspects, like human diseases. Now a days large amount of discoveries by ChIP-chip and other high-throughput techniques like this   may be connected with evolving bioinformatics to add to our knowledge of life and diseases.

Applications are invited for the post of a Project Fellow under UGC major Research project at CUP | M.Pharm

The Central University of Punjab, Bathinda (Punjab) has been established through the Central Universities Act 2009 which received the assent of the President of India on 20th March 2009. Its territorial jurisdiction extends to the whole State of Punjab. This newly set up Central University of Punjab (CUP) at Bathinda is poised to write new alphabet on the academic horizon of India. This University is one of the important links in the recently set up chain of Central Universities created in the educationally backward areas of India. Going to be an upwardly mobile organization, it is destined to emerge as a quality provider of teaching and research, knowledge and skills, products and services, attitudes and ethics.

Applications are invited for the post of a Project Fellow under UGC major Research project:

Post: Project Fellow- 1 Post (Centre for Chemical and Pharmaceutical Sciences)

Faculty Positions in Central University of Punjab

The Central University of Punjab (CUP), Bathinda will be having the Schools and Departments as given in Table-I. The University invites applications from eligible candidates for the posts of Professors (Pay Band Rs. 37400-67000 with AGP of Rs. 10, 000/-), Associate Professors (Pay Band Rs.37400-67000 with AGP of Rs. 9,000/-) and Assistant Professors (Pay Band Rs.15600-39100 with AGP of Rs. 6,000/-)

Job as Pharmacist in Central University of Punjab

The Central University of Punjab, Bathinda (Punjab) has been established through the Central Universities Act 2009 which received the assent of the President of India on 20th March 2009. Its territorial jurisdiction extends to the whole State of Punjab. This newly set up Central University of Punjab (CUP) at Bathinda is poised to write new alphabet on the academic horizon of India.

Job as Project Fellow in Central University of Punjab - M.Pharm. / M.S. (Pharm.)./ M.Sc

The Central University of Punjab, Bathinda (Punjab) has been established through the Central Universities Act 2009 which received the assent of the President of India on 20th March 2009. Its territorial jurisdiction extends to the whole State of Punjab. This newly set up Central University of Punjab (CUP) at Bathinda is poised to write new alphabet on the academic horizon of India.

Applications are invited for Degree in Pharmacy post of Pharmacist in PSACS - 2 posts

Punjab State AIDS Control Society (PSACS) was registered in 1998 for implementing National AIDS Control Programme. NACP is a 100% centrally sponsored project. PSACS started functioning in 1999. Principal Secretary Health is the Chairman of the Society Secretary Health has been designated as Project Director of the society. Additional Project Director is the technical head assisted by Joint Directors, Deputy Directors, Assistant Directors, other officers and supporting staff.

Applications on the prescribed proforma are invited for filling up following posts on contractual basis in various ART (Anti Retroviral Therapy) Centres in the State.

Post: Pharmacist

TILLING: VERSATILE REVERSE GENETIC TOOL

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About Authors:
Navgeet1, Balraj Singh Gill2, Arvind Negi3*, Shashi Shekhar Anand2
1Institute of Himalayan Bioresource and Technology (CSIR-IHBT), Palampur (HP)
2Centre for Biosciences Central University of Punjab, Bathinda (Punjab)
3Centre for Chemical and Pharmaceutical Sciences, Central University of Punjab, Bathinda (Punjab)
*arvindnegi2301@gmail.com, arvindnegicup@gmail.com

Abstract:
Recent years have been witnessedfor exhaustive genome sequencing, nourishing a cause to track the mutation and its consequences at the phenotypic level. Butreliabilityof these genomic studiesis the critical issuewhich is still unaddressed and not properly understood. Moreover via TILLING techniques (reverse genetic tool), can be valuable in evaluation of these studies to much extent. Usually TILLING account on a specific gene mutation in order to observe the extent of the functionality of that particular gene at morphological level. This review compiles the literature pertaining to the art of tilling in the evaluation of genomic studies and majorly in concern of functionalgenomics. Moreover this review also covers the example of the most common species so as to buildbetter understanding of the concept behind this technique of reversegeneticsand can be fruitfully applied in extractingthe ethano-botanical and therapeuticeffect of various medicinal plants.

INDOLE BASED ALKALOID IN CANCER: AN OVERVIEW

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About Authors:
Ramit Singla1, Arvind Negi1*, Virendra Singh2
1Centre for Chemical and pharmaceutical sciences, Central university of Punjab, Bathinda, India
2Department of Chemistry, National institute of technology, Jalandhar, India
*arvindnegi2301@gmail.com

Abstract:
Indole alkaloids are well characterized for diverse activities. Meanwhile, the present scenarioof disease depicting a different story, urge a call for novel scaffolds and pharmacophores. In recent years, indole based alkaloids gain significant importance in cancer chemotherapy and used as an adjuvant especiallyin case of Vinca alkaloids. These reports encourage the researchers for new finding related to indole based alkaloids to retrieve better scaffold for designing and synthesis of anticancer agents. However we tried to compile the literature which cover the recent reports and updates of indole based alkaloids targeting incancer. Moreover this review paperbrings new dimension and interface between the indole based alkaloids and their valuable commitment towards cancer targeting.

Walk in for M.Pharm or M.Sc in DST sponsored project as Junior Research Fellow in Central University of Punjab

The Central University of Punjab, Bathinda (Punjab) has been established through the Central Universities Act 2009 which received the assent of the President of India on 20th March 2009. Its territorial jurisdiction extends to the whole State of Punjab. This newly set up Central University of Punjab (CUP) at Bathinda is poised to write new alphabet on the academic horizon of India. This University is one of the important links in the recently set up chain of Central Universities created in the educationally backward areas of India. Going to be an upwardly mobile organization, it is destined to emerge as a quality provider of teaching and research, knowledge and skills, products and services, attitudes and ethics. It is gearing up to provide proper institutional leadership to the emerging demands of access, equity, relevance and quality in the mainstream University system. It has already flexed its muscles and initiated its first academic session.

Applications are invited for the post of Junior Research Fellow for DST sponsored project:

Post: Junior Research Fellow - 1 Post (Centre for Chemical and Pharmaceutical Sciences)

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