Ramit Singla1, Arvind Negi1*, Virendra Singh2
1Centre for Chemical and pharmaceutical sciences, Central university of Punjab, Bathinda, India
2Department of Chemistry, National institute of technology, Jalandhar, India
Indole alkaloids are well characterized for diverse activities. Meanwhile, the present scenarioof disease depicting a different story, urge a call for novel scaffolds and pharmacophores. In recent years, indole based alkaloids gain significant importance in cancer chemotherapy and used as an adjuvant especiallyin case of Vinca alkaloids. These reports encourage the researchers for new finding related to indole based alkaloids to retrieve better scaffold for designing and synthesis of anticancer agents. However we tried to compile the literature which cover the recent reports and updates of indole based alkaloids targeting incancer. Moreover this review paperbrings new dimension and interface between the indole based alkaloids and their valuable commitment towards cancer targeting.