GPAT 2016 | Question paper with key solutions

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106. Colloidal depression have which type of rheology
(a) Newtonian (b) Pesudoplastic (c) Non- Newtonian (d) Dilatant

107. Which of the reactive oxygen species is most dangerous to cells
(a) Singlet oxygen (b) Hydroxyl radical (c) Superoxide (d) Peroxide

108. The Gibb’s Phase rule
(a) Holds only for systems with more than components
(b) Predicts that a maximum of three phase can exits in one components system
(c) Does not count phase compositions as intensive variables
(d) Does not count pressure and temperature as intensive variables

109. Nerve impulse from the cochlea arrive first in which region of the brain
(a) Auditory cortex (b) Thalamus (c) Medulla oblongata (d) Inferior colliculus

110. The product of a Michael reaction of a ketone enolate to ana, b-unsaturated ketone is ............. And addition reaction occurs in a/an
(a) 1,5- deketone; 1,4-fashion
(b) α - substituted acetate; 1,2 fashion
(c) β - hydorxy keto; 1,3 – fashion
(d) α, β - keto ester; 1,5 – fashion

111. Which of the following is a drug considered as potassium sparing diuretic
(a) Trimatrine (b) Chlorthiazide (c) Mannitol (d) Furosemide

112. Which of the reagent from the given can be used to protect ketone group
(a) Acidic methanol (b) Basic methanol (c) Methanol + KCN (d) Phenobarbitone

113. Which of the following drugs causes less inhibition or REM sleep
(a) Zolpidem (b) Ethanol (c) Lorazepam (d) Phenobarbitone

114. The starting materials for synthesis of sulfamethoxazole are
(a) 4- Aminobenzene-1-sulfonyl amide + 3-chloro-5-methyl isoxazole
(b) 4- Aminobenzene-1-sulfonyl amide + 3-amino-5-methyl isoxazole
(c) 4- Aminobenzene-1-sulfonyl amide + 3-amino-5-methyl isoxazole
(d) 4- Aminobenzene-1-sulfonyl amide + 5-chloro-5-methyl isoxazole

115. Match the following plant product with their chemical class
(1) b-amyrin (P) Alkaloid secondary alcohol
(2) Sqaulene (Q) Alkaloid, phenol
(3) Morphine (R) Triterpene, secondary alcohol
(4) Ephedrine (S) Asyclic triterpene, polyene
(a) 1-R, 2-S, 3-Q, 4-P
(b) 1-S, 2-Q, 3-P, 4-R
(c) 1-P, 2-S, 3-Q, 4-R
(d) 1-R, 2-S, 3-P, 4-Q

116. All of the following except one are subject to therapeutic drug monitoring, Which one
(a) Phenytoin (b) Lithium (c) Gentamicin (d) Losartan

117. Thiamine deficiency causes decreased energy production because
(a) It is required for the process of transamination
(b) It is a co-factor in oxidative reduction
(c) It is a co-enzyme for transketolase is pentose phosphate pathway
(d) It is a co-enzyme for pyruvate dehydrogenase & alpha ketoglutarate dehydrogenase

118. Which of the following drugs are often found in both prescription and over-the-counter nasal decongestands
(a) Alpha 2 agonists (b) Alpha 1 agonists
(c) Alpha 1 antagonists (d) Beta 2 agonists

119. What is the surface tension of water of at 25oC
(a) 58 dyne/cm (b) 68 dyne/cm (c) 72 dyne/cm (d) 82 dyne/cm

120. Acridine and xanthene rings are related to each other in that..........
(a) Xanthene is oxygen isoster of acridine
(b) Acridine is oxygen isoster of xanthene
(c) Xanthene is nitrogen isoster of aciridine
(d) Xanthene is sulfur isoster os acridine

121. Colligative properties depend on...............
(a) Structural arrangement of atoms within the molecules of solute and solvent
(b) The number of solute particles is solution
(c) The physical properties of the solute particles dissolved is solution
(d) Sum of the corresponding properties of individual atoms or functional group within the molecules

122. In polarography..................current must be blocked
(a) Residual (b) Migration (c) Diffusion (d) None

123. The propellant commonly used in topical aerosols is
(a) Trichloromonfluoromethane (b) Trifluromonfluroethane
(c) Dichlordifluromthane (d) Isopropyl alcohol

124. Which of the following increase systolic and diastolic pressure in normal patient
(a) Epineherine (b) Norepinephrine (c) Tyramine (d) Phenylephrine

125. A large Reynold number is indication of which type of flow
(a) Smooth and stream line flow
(b) Laminar flow
(c) Steady flow
(d) Highly turbulent flow

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