GPAT 2016 | Question paper with key solutions

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76-125 questions are available below:

76. The most effective agent for treating psychosis would be
(a) Buspirone (b) Sertaline (c) Dextroamphetamine (d) Olanzapine

77. TGA is regulatory body of which country
(a) Europe (b) Australia (c) Canada (d) UK

78. Which prostaglandins have a keto function at C-9 and a α- Hydroxyl group at C-11 in prostanoic acid backbone
(a) PGA (b) PGI (c) PGE (d) PGF

79. When morphine is heated at 140oC under pressure, with strong HCL, it converts pnto:
(a) Morphinone (b) Apomorphine (c) Codeine (d) Oxymorphine

80. All of the following are gram-negative rods EXCEPT
(a) Clostridium (b) Escherichia (c) Salmanella (d) Shigella

81. The cells which secrets male sexhormone testosterone are:
(a) Crypts of lieberkuhn (b) Escherichia (c) Salmonella (d) Shigella

82. If QA and QC are compared
(a) Both are literally the same
(b) QA is a higher activity in the management hierarchy
(c) QA is a higher activity in the management hierarchy
(d) QA is a done by the production person and QC is done by analyst

83. Bio availability of drug refers to
(P) The ratio of drug excreted unchanged in urine to that excreted as metabolites
(Q) Fraction of the drug reaching the target to produce the action
(R) The length of time an administered drug is available for action
(S) Percentages of administered dose that reaches systemic circulation in the unchanged form
(a) Only P (b) Q and R (c) R and S (d) Only S

84. Following intravenous administration, drugs are distributed fastest to
(a) The skin, kidney, and brain
(b) The liver, kidney, and brain
(c) The liver, adipose, and brain
(d) The liver, kidney, and adipose

85. Which of the following agents act as hypoglycemic as ATP sensitive potassium channel blocker
(a) Mitiglinide (b) Pioglitazone (c) Liraglutide (d) Sitagliptin

86. Carabilide shows stongs IR absorption in which of the following range in cm-1
(a) 3200-3600 (b) 1640-1690 (c) 1000-1300 (d) 2210-2260

87. Match the drugs with their adverse effects
(1) Cyclophosphamide (P) Pulmonary fibrosis
(2) Doxorubicin (Q) Nephrotoxicity, ototoxicity
(3) Bleomycin (R) Acute hemorrhage cystitis
(4) Cisplatin (S) Cardiotoxicity
(a) 1-S, 2-R, 3-P, 4-Q (b) 1-P, 2-Q, 3-S, 4-R (c) 1-P, 2-S, 3-Q, 4-R (d) 1-R, 2-S, 3-P, 4-Q

88. Which one of the following technique is used to determine glass transition temperature
(a) X-ray diffractometry
(b) Raman spectroscopy
(c) Differential scanning calorimetry
(d) Atomic forced microscopy

89. Match the schedules with the particulars they describe
(1) Schedule T (P) Standards for patent or proprietary medicines
(2) Schedule U (Q) Requirements/ guidelines to import &/or manufactures new Drug
(3) Schedule V (R) GMP practices for Ayurvedic, siddha & Unani medicines
(4) Schedule Y (S) Particulars to be shown in the manufacturing records
(a) 1-R, 2-S, 3-Q, 4-P (b) 1-S, 2-Q, 3-P, 4-R (c) 1-R, 2-S, 3-P, 4-Q (d) 1-S, 2-R, 3-P, 4-Q

90. Which of the following UV rays cause cancer
(a) UVA (b) UVB (c) UVC (d) All of the above

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