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  • DTK OF MEDICINES FROM BIO-PIRACY: ITS CONSCIENTIOUSNESS BY TKDL OF INDIA

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    ABOUT AUTHORS:
    NG Dhawan*1, Manisha Mavai2, Priyanka Bishnoi3, Raaz K Maheshwari3
    1Amity Institute of Environmental Sciences, Amity University,  Noida, UP, India
    2Department of Botany Physiology, AIIMS, Jodhpur, Rajasthan, India
    3Department of Botany & Biotechnology, University of Rajasthan, Rajasthan, India
    4Department of Chemistry, SBRM Govt PG College, Nagaur, India
    *rkmgreenchem.jaipur@gmail.com

    ABSTRACT
    The genetic resources and indigenous communities traditional knowledge of developing countries is being exploited by the Developed countries in the name of patents for inventions that are derived from genetic  resources. The exploitation of genetic resources and indigenous communities traditional knowledge by the developed countries in the name of patents on the inventions derived from those genetic resources is actually bio-piracy.  Protection of the TK of the local and indigenous communities appears to be one of the most debatable and complex issues. This paper brings out the role of domestic IPR constitution that looks to protect traditional system of medicine and associated TK in Indian sub-continent. Further, it attempts to validate the necessity of introduction of a national TKDL, which can be utilized as an evidence of the 'prior art' by the examiners of patent offices, nationally as well as internationally. Thus, it aims to address the concerns relating to the creation of TKDL in India.

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  • PHARMACOLOGY OF COMBINED RANOLAZINE AND AMIODARONE HYDROHLORIDE THERAPY TO TREAT ATRIAL FIBRILLATION
  • A REVIEW ON: PHYSICOCHEMICAL EVALUATION OF AYURVEDIC MINERAL DRUG TANKAN BHASMA
  • ZERO ORDER AND FIRST ORDER DERIVATIVE SPECTROSCOPIC METHOD FOR SIMULTANEOUS ESTIMATION OF MOXIFLOXACIN HYDROCHLORIDE AND KETOROLAC TROMETHAMINE IN SIMULATED TEAR FLUID
  • ADVANCEMENT IN HAIR CARE

    ABOUT AUTHOR:
    Vinay Kumar Singh
    General Manager-Technical,
    Mikasa Cosmetics Limited,
    Ahmedabad, Gujarat
    vinay.s@mikasacosmetics.com

    Before trying to understand advancement in Hair Care, Let us try to know basics about Hair.

    For mammals, fur provides an insulating coat for the conservation of body heat.  The ape RAMAPITHECUS as they left the forest and moved to the Savannah, started a march towards nudity, the hair on the body became sparser and shorter due to adaptability.  The hair was not lost from all over the body. The eyebrows and the eyelashes remained. The hair on the scalp remained as a protection from midday sun, for an animal who can stand and walk on its own two feet. The beard remained as a badge of maleness and in both sexes, the genital and axillary hair remained as it was probably associated with glandular scent producing units.

  • BIO-MARKERS AND BIO-SENSORS: UNRAVELLING THE MAJOR MECHANISTIC INTERVENTIONS IN CANCER PROGNOSIS
  • A REVIEW ON ANALYTICAL METHODS FOR RANOLAZINE DETERMINATION IN SYNTHETIC MIXTURE
  • EFFECTS OF GARLIC EXTRACTS ON THE MYOCARDIUM OF LEFT VENTRICLE OF THE HEART OF HIGH SALT FED ADULT WISTAR RATS

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    ABOUT AUTHORS:
    *Saka, O. S; Olayode, A. A; Adelodun, S. T
    Department of Anatomy and Cell Biology,
    Faculty of Basic Medical Sciences, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria.
    olusolasaka1@gmail.com

    ABSTRACT
    This study was designed to evaluate the effects of garlic extracts on the morphology of myocardium of left ventricle of the heart and also determine the body weight and relative weight of the organs on high salt fed adult Wistar rats. Twenty-five healthy female Wistar rats weighing 130-180 g were randomly assigned into 5 groups of 5 rats each (Groups A, B, C, D and E). Rats in group A was fed with standard laboratory pellets, while groups B, C, D and E were fed on the high-salt diet for five weeks. Thereafter, daily administration of 50 mg kg-1, 100 mg kg-1 and 150 mg kg-1 of the garlic extract were giving orally to groups C, D and E respectively for 3 weeks. The rats were sacrificed under ketamine anesthesia (5mg/kg i.m). The left ventricle of the heart was excised, processed routinely in paraffin wax and stained with routine special stained. Result showed significant decreased (p<0.05) in weight of all high salt fed groups when (F=46.90, p<0.05) compared with control. Whereas, treatment with garlic extract help in weight management in high salt fed+garlic extract treated groups and also no significant difference (p<0.05) in the relative heart weight when (F=1.773, p<0.05) compared the control with other groups. Histological results revealed morphological alterations in the left ventricle in high salt fed group. In conclusion, Garlic extract has ameliorative property at the level of 100 mg kg-1 or 150 mg kg-1 of the extract on high salt fed induced cardiac injury.

  • HEAVY METALS AND OTHER CONTAMINANTS IN COSMETICS & PERSONAL CARE PRODUCTS, ITS HARMFUL EFFECT AND ITS REGULATION

    ABOUT AUTHOR:
    Vinay Kumar Singh
    General Manager-Technical,
    Mikasa Cosmetics Limited,
    Ahmedabad, Gujarat
    vinay.s@mikasacosmetics.com

    A contaminant is a substance that is where it shouldn't be and is at high enough levels to have a negative effect on our health or on the health of animals or plants. A contaminant is any potentially undesirable substance (physical, chemical or biological). It usually refers to the introduction of harmful human-made substances.

  • COMMONLY USED MEDICINAL PLANTS IN TEHSIL PACHHAD, DISTRICT SIRMOUR, HIMACHAL PRADESH
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