Pharmacology Articles

About Authors:
Madhuri Sharma*¹, KC Mathur¹, Rajnee², Raaz K Maheshwari^3
1Department of Physiology, Sardar Patel Medical College, Bikaner, Rajasthan
²Department of Physiology, Sarojini Naidu Medical College, Jodhpur, Rajasthan
³Department of Chemistry, SBRM Govt PG College, Nagaur, Rajasthan
*madhurisharma26@gmail.com

Abstract
Pulmonary function test are affected by the obesity. Various studies demonstrate important modifications in the pulmonary function tests of obese adults and adolescents, there is scarce information on obese children, and the findings remain inconclusive. Although there are some studies which demonstrate important modifications in the respiratory pattern of obese children, but there are some contradictory findings. So such type of study should be done which give us different and separate findings for overweight, mild obese, moderately obese, and morbidly obese criteria in obese school children in comparison with age, sex and ethnically matched control group.

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About Authors:
T. Vishnuvaravidyadhar*, M. Sushma, R. Mohanraj, M. Babu  
Department of Pharmacy Practice,
Raghavendra Institute of Pharmaceutical Education & Research, RIPER
K R Palli Cross, Near S.K University,
Anantapuramu District, Andhra Pradesh, INDIA
*vishnuvaravidyadhar@gmail.com

Abstract:
Geriatrics is more prone to higher risks of chronic illness and are using multiple medications in order to lead healthy life. Polypharmacy increases the risk of adverse drug events, as a result changes takes place in physiological, social, physical and functional decline in the body. These rapid physiological changes make elderly patients unable to cope with body stresses. Drug toxicity, side effects and adverse drug reactions appear more frequently and are more life-threatening in elderly patients. Tetracyclins, streptomycin, reserpine, and all barbiturates are to be contraindicated in geriatrics in order to prevent further complications. Polypharmacy is the simultaneous taking of many medications, has been well documented and is a topic of much concern for those looking to improve the quality of care for the elderly. Elderly patients often develop complicated conditions and multi-factorial health states that require extensive pharmacotherapy, sometimes surgery leaving the population at risk for exposure to drug-drug interactions, drug-food interactions and other adverse events. Previously literature states that rate of adverse events are directly proportional to number of drugs taken by the patient. To manage all these complications and to avoid polypharmacy Dose regimen should be simple and drugs should be given in combinations to improve patient compliance.