JUN 2014 ARTICLE LIST >>
PharmaTutor (June- 2014)
ISSN: 2347 - 7881
Received On: 10/04/2014; Accepted On: 18/04/2014; Published On: 01/06/2014
AUTHORS: Pankaj Kushwah1*, Nandu Kayande2
1Department of Pharmacognosy
2HOD Department of Pharmacology
Nimar Institute of Pharmacy, Dhamnod,
Dhar, Madhya Pradesh, India
*Pankajnipd@gmail.com
ABSTRACT:
Antiulcer activity of aqueous extracts of Annona squamosa seed extract was studied in Rats by pyloric ligation method. The extract at dose of 100,200 mg/kg produced significant inhibition of gastric lesion induced by Pylorus ligation induced ulcer. The parameters taken to assess anti-ulcer activity were volume of gastric secretion, PH, free acidity, total acidity and ulcer index. The results indicate that the alcoholic extract significantly (P < 0.001) decreases the volume of gastric acid secretion, PH, free acidity, total acidity and ulcer index with respect to control.
How to cite this article: P Kushwah, N Kayande; Antiulcer Activity of Annona Squamosa Seed Extract in Experimental Rats; PharmaTutor; 2014; 2(6); 174-176
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