Savitribai Phule Pune University, one of the premier universities in India, is positioned in the North-western part of Pune city. It occupies an area of about 411 acres. It was established on 10th February, 1949 under the Poona University Act. The university houses 46 academic departments. It is popularly known as the 'Oxford of the East'. It has about 307 recognized research institutes and 612 affiliated colleges offering graduate and under-graduate courses.

Syngene International is one of India’s premier contract research and manufacturing organizations in providing customized service. Our services encompasses all across discovery chain: early stage discovery, process development, cGMP manufacturing and formulation development both in the small molecule and novel biologics area. Based in Bangalore, Karnataka, the Company is situated in a 90 acre Special Economic Zone with over 100000 sq. mt of built up facilities. The state-of-the-art research facilities have been qualified by various pharmaceutical majors & regulatory agencies and has received various certifications including ISO 9001: 2008, ISO 14001:2004, OHSAS 18001:2007, GLP and AAALAC.

Post : Instrument Data Manager

PAREXEL has supported the Bio-Tech and Pharmaceutical industries in helping the development of new drugs and treatments on a global basis. As a leading global biopharmaceutical service provider, they supply knowledge-based contract research, medical communications and consulting services across a broad range of therapeutic areas to the worldwide pharmaceutical, biotechnology and medical device industries. They have helped over 800 clients to develop and launch some of the most important drugs and devices of our time-helping people live better and healthier lives everywhere in the world. Headquartered near Boston, Massachusetts, PAREXEL operates in more than 50 countries around the world.

Post : Medical Writer II

ABOUT INSTITUTE
Indubhai Patel College of Pharmacy and Research Centre, was started in the year 2006 with vision to provide an education in the vicinity of Charutar region, by Sanskruti Sanraksha Charitable. The institute imparts quality Pharmacy education at Graduate, Post graduate and Doctorate level with approved courses by AICTE, PCI & GTU like B. Pharm, M. Pharm and Pharm D, (Doctor in Pharmacy), respectively. We have well-equipped laboratories and excellent infrastructure and have adopted modem teaching techniques. The institute houses state of art research facility and infrastructure to support pharmaceutical Education and Research. The institute focuses on value added education, development of skill of students in addition to development of ethics and character.

The National Anti-Doping Agency (NADA) is an autonomous body under the Ministry of Youth Affairs and Sports, Government of India and is the nodal agency for implementation of AntiDoping programme in the country within the policy frame work of the Government. The primary functions of this organisation are to implement the Anti-Doping rules, to coordinate dope testing program through the participating stakeholders and to promote anti-doping research and education to inculcate the value of dope free sports.

National Anti Doping Agency (NADA) invites applications on plain paper along with all details from Indian Citizens for recruitment of Technical Officers on contract basis. The job description, education qualification etc are as under.

Post : Technical Officer

The Birla Institute of Technology & Science, BITS Pilani is an all-India Institute for higher education. The primary motive of BITS is to "train young men and women able and eager to create and put into action such ideas, methods, techniques and information". The Institute is a dream come true of its founder late Mr G.D.Birla - an eminent industrialist, a participant in Indian freedom struggle and a close associate of the Father of Indian Nation late Mr. Mohandas Karamchand Gandhi (Mahatma Gandhi). What started in early 1900s as a small school, blossomed into a set of colleges for higher education, ranging from the Humanities to Engineering until 1964 when all these colleges amalgamated to culminate into a unique Indian University of International standing. This university was christened as the Birla Institute of Technology and Science, Pilani, known to many as BITS, Pilani.

Post : Junior Research Fellow

Every day, around the world, people reach for Unilever products. Our brands are trusted everywhere and, by listening to the people who buy them, we've grown into one of the world's most successful consumer goods companies. In fact, 150 million times a day, someone somewhere chooses a Unilever product. Look in your fridge, or on the bathroom shelf, and you’re bound to see one of our well-known brands. We create, market and distribute the products that people choose to feed their families and keep themselves and their homes clean and fresh.

Post : Asst R&D Manager

The St. John's Research Institute (SJRI) is a part of the St John's National Academy of Health Sciences, which is run by the CBCI Society for Medical Education. From its inception, St. John's has set before it an ideal of excellence in academic courses as well as service to society as a result of which it has truly become holistic both in its outlook and in its approach to the problems of community health, In 2000, the Academy decided that its commitment to excellence in research required the setting up of an Institute that was dedicated to the pursuit of research and capacity development in St. John's.

Post : Project Assistant

THE FAIR PRICE PHARMACY has been established as a retail pharma company in India. Our business model is based on the accomplishment of providing the fairprice for certified medicines, healthcare equipment to the customers in the entire country. Our endeavor is to offer customers a value added experience by providing educated solutions for their everyday medicines needs with the help of interactive programs and trustworthy professionals.

Post : Pharmacists

Ultratech India Limited is a WHO-GMP and ISO certified Pharmaceutical company that manufactures and markets a wide range of Pharmaceutical Formulations in various dosage forms (Tablets, Capsules, Syrups, Gels, Injections, Nasal Sprays, Metered Dose Inhalers), advanced Drug Intermediates and Active Pharmaceutical Ingredients.

Post : International Sales Executive or SR. Executive

AIIMS is one of the SIX AIIMS like apex healthcare institutes being established by the Ministry of Health & Family Welfare, Government of India under the Pradhan Mantri Swasthya Suraksha Yojna (PMSSY). With the aim of correcting regional imbalances in quality tertiary level healthcare in the country, and attaining self sufficiency in graduate and postgraduate medical education and training the PMSSY planned to set up 6 new AIIMS like institutions in under served areas of the country.

Online applications are invited in prescribed proforma from suitable candidate for filling up following Group 'A', 'B' & 'C' posts on DIRECT/DEPUTATION RECRUITMENT BASIS in All India Institute of Medical Sciences, Virbhadra Marg, Rishikesh, Uttarakhand - 249203.

Post : Pharmacist Grade II

Mohalla Clinics are primary health centres in the state of New Delhi in India, that offer a basic package of essential health services including medicines, diagnostics, and consultation free of cost. Mohalla in Hindi means neighborhood or community. These clinics serve as the first point of contact for the population, offer timely services, and reduce the load of referrals to secondary and tertiary health facilities in the state. Mohalla Clinics was first set up by the Aam Admi Party government in 2015, and as of 2018, 187 such clinics have been set up across the state and served more than 2 million residents. The Government has kept a target of setting up 1000 such clinics in the city before 2020 Delhi Legislative Assembly Elections. According to the World Health Organization data for the year 2015, more than 65% of the population in India paid for health from their own pockets.

NIPER is the fifth Institute to be included in the list of premier Institutes under the Department of  Pharmaceuticals, Ministry of Chemicals & Fertilizers, Govt. of India. The NIPER started functioning  from the month of September, 2008.  The Institute is presently housed at the NIPS, Mirza, Kamrup, Assam. The  Institute has excellent facilities for advanced Education and Research in Pharmaceutical Sciences and is looking  for Project/Non Teaching Staff with good experience to contribute in building this Institute as one of the best  Centers for Excellence. Presently the Institute is offering M.S (Pharm.) and Ph. D Programmes in five branches  and planning to expand further.

The Tata Memorial Centre (TMC) is a Comprehensive Cancer Centre with a mission to achieve the highest standards in patient care, cancer prevention, cancer research and professional development for oncology and allied disciplines. TMC is an autonomous body funded, controlled by the Department of Atomic Energy, Government of India. TMC is affiliated to Homi Bhabha National Institute (HBNI). The HBNI is a Deemed University of the Department of Atomic Energy with a mission to develop high quality postgraduate educational programs in science and technology including those related to life and health sciences.

TMC invites applications from eligible candidates of Indian nationality, who are keen to pursue a career in TMC.

Translational Health Science and Technology Institute (THSTI) is an autonomous Institute of the Department of Biotechnology, Ministry of Science and Technology, Govt, of India. The institute is an integral part of the interdisciplinary NCR Biotech Science Cluster located at Faridabad, and is designed as a dynamic, interactive organization with the mission to conduct innovative translational research and to develop research collaborations across disciplines and professions to translate concepts into tangible products to improve human health.

Post : Research Associate

{ DOWNLOAD AS PDF }

ABOUT AUTHORS
R. Mishra¹, P. Barad¹, N. Patel², N. Patel³*
¹Department of Pharmacy,
Shree S.K. Patel College of  Pharmaceutical  Education & Research
Ganpat University, Kherva, Mehasana Gujarat
²Department of Pharmacognosy,
Shree S.K. Patel College of  Pharmaceutical  Education & Research
Ganpat University, Kherva, Mehasana Gujarat
³Department of Pharmacology,
Shree S.K. Patel College of  Pharmaceutical  Education & Research
Ganpat University, Kherva, Mehasana Gujarat

ABSTRACT
Worldwide cancer is the major cause of death. Almost 8.8 million people died due to different types of cancer such as lung cancer, liver cancer, breast cancer, stomach cancer, blood cancer etc. in 2015. Government of various countries and some private organizations are spending trillions dollars for the research in cancer.  According to report of WHO treatment cost of cancer is approximately US$ 1.16 trillion per year and this amount is increasing per year. Despite of huge work the exact cause of genesis is still unknown. Couples of therapies like chemotherapy, radiation, surgery and targeted therapy are available with some detrimental effect. Now scientists are seeking lead molecule from naturally occurring substances due to high safety margin as compared to current approaches. Natural phytochemicals are prominent strategy for prevention, treating, and curing cancer. There are many phytochemicals from herbs having potent anticancer property. Generally these phytochemicals treat cancer by different mechanisms like augmenting apoptosis, cell cycle arrest, targeting to some specific cancer inducing proteins, increasing cytotoxicity etc. This is our little attempt to gather information of phytochemicals having anticancer property such as Etoposide, Curcumin, Vincristine, etc. with postulated mechanism. Etoposide is effective in lung cancer, ovarian cancer by inhibiting type II Topoisomerase. Various research revealed that Curcumin is effective in different types of cancers by increasing apoptosis and targeting specific gene such as MDM2 oncogene is inhibited through the ETS2 transcription factor by modulation of signaling pathway PI3K/mTOR in breast cancer. Vincristine shows anticancer property by oncogenic EWS-FLI1 fusion protein inhibition which cause G2-M phase cell cycle arrest & reduce tumor. This review depicts few phytochemicals having anticancer property such as Etoposide, Curcumin, vincristine, etc. with possible mechanism.

CDRI is considered to be a pioneer research organization in the field of biomedical research where all the infrastructure and expertise are available to develop a drug right from its concept to market. The very latest techniques and methodologies are employed for developing drugs, diagnostics and vaccines to combat diseases prevalent among mankind in general and Indian population in particular. CDRI is a multidisciplinary research laboratory consisting of scientific personnel of various areas of biomedical sciences. For administrative and scientific purposes the Institute's manpower has been grouped into 17 R&D divisions and few divisions providing technical and scientific support.

Rajendra Memorial Research Institute of Medical Sciences, Agamkuan, Patna 800 007, a permanent Institute of Indian Council of Medical Research, Department of Health Research, Ministry of Health & Family Welfare, Govt. of India, invites online applications from suitable candidates for appointment on the Group A Scientific posts as mentioned below.

Teerthanker Mahaveer University is a Jain Minority State Private University established by Act No. 30 of 2008 of the Government of Uttar Pradesh and has been approved by University Grants Commission (UGC) under Section 2(f) of UGC Act, 1956. The university is located on National Highway-24 and is barely 144 Kms from National Capital, New Delhi. The University stand committed to the ideals of Lord Mahaveer i.e. Right Philosophy, Right Knowledge, and Right Conduct in all its operations and aspires to be recognized as an ultimate destination for world-class education.

Post : Professor / Associate Professor / Assistant Professor