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ABOUT AUTHORS
A. PADMA¹*, D. GIRIJA², A. THIRUPATHIREDDY³, B. VENKATESWARAREDDY^4
1Department of Pharmaceutical Analysis, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta(M), Prakasam (Dist) Andhra Pradesh, India
²Department of Pharmaceutical Analysis, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta(M), Prakasam (Dist) Andhra Pradesh, India
³Department of Pharmaceutics, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta(M),Prakasam(Dist) Andhra Pradesh, India
⁴Department of Pharmaceutics, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta(M), Prakasam(Dist) Andhra Pradesh, India

ABSTRACT
The present research work deals with the development  and validation of  stability indicating RP-HPLC method for the simultaneous estimation of Aceclofenac and Drotaverin.HCl in bulk and formulation. Chromatographic separation was achieved on ODS HG-5 RP   C18(250 X 4.6 mm, 5 µm) using the mobile phase consisting of Acetonitrile and1% triethylamine (TEA) in the ratio of 90:10 pH  2.16 adjusted with Ortho phosphoric acid. The mobile phase was pumped at a flow rate of 1.0 mL/min and UV detection was observed  at 224 nm. The retention time was found to be 3.57 min for Aceclofenac and 6.15 min for Drotaverin.HCl. The linearity concentrations are obtained from in the range of 30-70 µg/ml for Aceclofenac and 24-56 µg/ml for Drotaverin.HCl respectively with correlation coefficient was 0.999 and 0.998. The proposed method was found to be simple, accurate, precise and reproducible and developed method can be suggest to routine quality control analysis for simultaneous estimation of Aceclofenac and Drotaverin.HCl in pharmaceutical dosage forms.

Walk-In-Interview will be conducted as scheduled below for filling up the following posts under Rastriya Bal Swasthya Karyakram (RBSK) National Health Mission, Koraput on contractual basis for a period of 11 months with monthly remuneration as noted against each and subject to renewal as per OSH&FW Society terms and conditions.

Post : Pharmacist, RBSK

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The Birla Institute of Technology and Science, Pilani (BITS Pilani) is an all-India Institute for higher education. Founded in 1964 in collaboration with Massachusetts Institute of Technology (MIT), USA, it is one of the top most educational Institute in India.  The institute is one among the 6 Indian 'Institutes of Eminence' recognized by the Government of India in 2018. It is established across 4 campuses and has 15 academic departments. The BITS, Pilani - K. K. Birla Goa Campus, is about 10 kms south of Vasco-da-Gama, 20 kms north of Margaon and 7 kms east of Goa Airport, along National Highway – 17B, Bypass road.

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The State Health Society, Bihar intends to invite applications for the appointment of Additional Director-PPP, Deputy Director-MCH and Assistant Director-Referral Transport on contractual basis, initially for 11 months which may be extended up to 3 years or more depending on candidate’s satisfactory performance, availability of funds and sanction of the post under NATIONAL HEALTH MISSION.

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Bihar College of Pharmacy established in the year of 1979 is one of the best institutions for the students who want to pursue an excellent career in Pharmacy . Bihar College of Pharmacy is permanentally affiliated to Magadh University, Bodh-Gaya, Pharmacy Council of India, New Delhi and also Approved by All India Council For Technical Education, Ministry of Human Resources Development, Govt.of India, New Delhi & Department of Health , Govt .of Bihar. The College has already been recognised under section 2(f) and 12(B) of the University Grant Commission Act, 1956 by the University Grant Commission, Government of India.

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