About Authors: K.Venkatakrishna
Department of Pharmaceutics; Koringa college of pharmacy,
Korangi (Andhra Pradesh) India. venky5019@gmail.com
Abstract:
Venlafaxine HCl is an anti depressent drug which is used in depreesion. It is available both as immediate release tablet as well as modified release product. The innovator modified release product available in international market is Effexor ER tablets. Effexor ER is based on erosion matrix system. The core tablet is coated with Ethyl Cellulose using PVP as a core former. This coating is solvent based coating. The aim of present investigation was to prepare a ER tablet of Venlafaxine HCl with similar dissolution profile matching to Effexor ER using swelling matrix system. The platform developed for this product was compression coating. An immediate release core tablet of 100mg was prepared and it was compression coated using HPMC matrix system. HPMC of three viscosity grades was selected and the concentration and the viscosity grade were optimised. Similarity factor ( F2 values) with innovator product were calculated for in vitro dissolution profile. The rank order correlation for similarity factor was as under HPMC K15M 15% > HPMC K100M 15% > HPMC k15M 35% > HPMC k100M 35% > HPMCK 4M 15% > HPMC k45 45%. In this review, current and recent developments of venlafaxine hydrochloride extended release products are discussed.
Abstract
Nutrition before and during pregnancy has a profound effect on the development of infants. This is a rather critical time for healthy fetal development as infants rely heavily on maternal stores and nutrient for optimal growth and health outcome later in life. Prenatal nutrition addresses nutrient recommendations before and during pregnancy. Birth weight of the newborn at delivery reflects the sufficiency and the quality of maternal nutrient for the fetus during pregnancy. Prenatal nutrition has a strong influence on birth weight and further development of the infant.The present paper reviews the role of prenatal nutrition in pregnancy.
About Authors: G. Sowjanya*, P. Ramaa Bharathi, Dr.A.M.S.Sudhakar Babu
A.M.Reddy memorial college of pharmacy,
Narasarao Pet. Sowjanya.gedagamma@gmail.com
ABOUT AUTHORS: 1Kumari Jyothsna*, 2N.Chandana 1,2Department of Pharmaceutical Analysis and Quality Assurance,
Nimra College of Pharmacy, Jupudi, Vijayawada, A.P, India jyothsna.s.k24@gmail.com
About Authors: Sumana Majumdar
M.Pharm(Pharmacology)
Department of Pharmacology
NSHM Knowledge Campus, Kolkata Group of Institution,
124 B.L. Saha Road, Kolkata –700053, West Bengal, India. sumana.majumder03@gmail.com
ABOUT AUTHORS: 1Vinjam Swathi* 2Nanda Kishore Agarwal 1M pharmacy, Department of Pharmaceutical Analysis and Quality Assurance, Nimra College of Pharmacy, Jupudi, Vijayawada, A.P, India 2Professor and head of the department of pharmaceutical chemistry, Nimra College Of Pharmacy, Jupudi, Ibrahimpatnam, Vijayawada, A.P, India
About Authors: Deepti Soni*, Rathore KS1, Nema RK2
*College of Pharmaceutical Sciences, Behrampur, Orissa 1BN Institute of Pharmaceutical Sciences, Udaipur, Raj. 2Rishiraj College of Pharmacy, Indore-MP *deepti_jazz@yahoo.com