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  • PHYTOCHEMICAL ASSESSMENT OF THE AQUEOUS AND METHANOLIC EXTRACTS OF SOME HERBAL PLANTS IN JOS, NIGERIA

    About Authors:
    Enegide Chinedu*, David Arome, SolomonF. Ameh
    Department of Science Laboratory Technology (Physiology & Pharmacology Technology),
    University of Jos, Jos Nigeria.
    chinex.snow@gmail.com

    Abstract
    Phytochemicals are referred to as pharmacologically active substances which are naturally present in plants. However, the effects of various plant preparations in the body when administered, is dependent on the phytochemicals present. Herbal medicine have been said to be the oldest form of medicine and have of recent even gained new momentum due to its advantages.The World Health Organization has recognized that traditional herbal plants may be useful in an integrated health care deliverysystem in several countries. But however to achieve the goal of using both herbal medicine and modern medicine paripassu, there is need for the phytochemical assessment of the plants coupled with pharmacological and toxicological investigations as well. Therefore, the aim of this research is to evaluate the phytochemicals present in the aqueous and ethanolic extracts of some herbal plants in Jos, Nigeria. This study have unveiled the presence of various phytochemcals in the different plant extracts examined. The various phytochemicals present in the extracts includes alkaloids, saponins, tanins, flavonoids, carbohydrates, steroids, cardiac glycosides and anthraquinones. These phytochemicals are known to posses therapeutic and also physiological activity. The test have shown that the plants are useful as they contain phytochemicals capable of producing valuable pharmacological effects. However, further studies aimed at establishing the dosage in which the may produce their pharmacological effects and toxicity should be done. Studies aimed at isolating the phytochemicals and screening their individual effects will also be very useful.

  • RECESSIVE DYSTROPHIC EPIDERMOLYSIS BULLOSA

    ABOUT AUTHOR:
    Akshay Rajgaria
    Kanak Manjari Institute of Pharmaceutical Sciences
    Rourkela, Orissa
    akshaykrish2007@gmail.com

  • DESIGN, DEVELOPMENT AND CHARACTERIZATION OF pH SENSITIVE HYDROGEL FOR INTESTINAL DELIVERY OF PREDNISOLONE

    ABOUT AUTHORS:
    Patel Juhi D.*, Dr. A.K.Seth, Sachin P Chauhan, Nirmal Shah, Ankur Javia, Chintan Aundhia
    Department of Pharmacy, Sumandeep Vidyapeeth University,
    At & Po Pipariya, Ta- Waghodia, Dist. Vadodra-391760.(Gujarat) India
    pateljuhi63@yahoo.com

  • DEVELOPMENT & EVALUATION OF TRANSDERMAL DRUG DELIVERY

    ABOUT AUTHOR:
    Rakesh Kumar Sati
    M.Pharm D.I.T Faculty of Pharmacy
    Dehradun Uttarakhand
    rakeshsatiq.a@gmail.com

  • EXPERIMENTAL DESIGN

    ABOUT AUTHORS:
    *Rakesh Gupta, Hemant Kumar Sharma, Manvendra Jaiswal, Rajeev Sharma, Narendra Nyola, Dr. Rajesh Yadav
    Alwar Pharmacy College, M.I.A. Alwar,
    Rajasthan, India 301001
    rakeshapcpharma@gmail.com

  • FORMULATION AND EVALUATION OF QUETIAPINE FUMARATE SUSTAINED RELEASE MATRIX TABLET

    ABOUT AUTHORS:
    Pranita T. Gaikwad*, Reshma R.Patil, Mr M.M.Nitalikar, Dr.S.S.Patil, Dr.S.K.Mohite
    Rajarambapu college of pharmacy,
    kasegaon-415404. MH
    *pranitatgaikwad@gmail.com

  • THE ROLE OF SECONDARY MESSENGER SYSTEM IN SIGNAL TRANSDUCTION

    About Authors:
    Mr. Salahuddin Mohammed
    Associate Professor of Pharmacology, College of Health Sciences,
    Department of Pharmacy, Mizan Tepi University,
    Mizan Teferi, Ethiopia.
    salahuddin_pharma48@yahoo.com

  • FORMULATION AND EVALUATION OF ESOMEPRAZOLE MAGNESIUM DELAYED RELEASE TABLETS 40 MG

    ABOUT AUTHORS:
    *1MR.B.Ashok, 2Dr.K.S.Manjunatha Shetty, 3Dr. Manikanta kumar, Chandra Shekar
    1Master of Pharmacy in Pharmaceutics
    2Ph.D Professor and Principal
    3Ph.D, Associate Professor
    Jawaharlal Nehru Technological University, Hyderabad
    Srinivasa Pharmaceutical Institute And Center For Research Burugupally, Vikarabad, R.R Dist, A.P.
    ashok.belde@gmail.com

    ABSTRACT
    The present study was an attempt to formulate and evaluate enteric coated tablets for esomeprazole magnesium dihydrate. Different core tablets were prepared and formulation was selected for further enteric coating, based on the disintegration time. Seal coating was applied to achieve 3% weight gain. Enteric coating was carried out using different polymers like hydroxyl propyl methylcellulose phthalate to achieve 5% weight gain. Disintegration studies showed that the formulations failed in 0.1 N HCl media. Hence the quantity of enteric coating was increased to 8% w/w. In vitro analysis of the developed tablets was carried out. Results from disintegration time and dissolution rate studies indicate that all the esomeprazole enteric tablets prepared possess good integrity, desirable for enteric coated tablets.

  • GOODPASTURE SYNDROME

    ABOUT AUTHOR:
    Akshay Rajgaria
    Kanak Manjari Institute of Pharmaceutical Sciences
    Rourkela, Orissa
    akshaykrish2007@gmail.com

    ABSTRACT:
    Patients with Goodpasture’s syndrome presenting with dialysis-dependent end-stage renal failure at diagnosis almost never regain independent renal function. We report a patient with a 100% crescentic lesion in whom reversal of dialysis dependence was achieved by immunoadsorption together with immunosuppression. In a second patient, early initiation of immunoadsorption was able to completely restore normal renal function as early as 1 month after the start of treatment. These data give evidence of the use of immunoadsorption as a hopeful alternative to conventional plasma exchange in patients with Goodpasture’s syndrome showing advanced renal failure.

  • A REVIEW ON DETERMINATION OF PRESERVATIVES IN FOOD STUFFS BY DIFFERENT ANALYTICAL METHODS

    ABOUT AUTHORS:
    V.Surekha1, V.S.Thiruvengada Rajan1, C.Madhusudhan Chetty2
    1Dept of pharmaceutical analysis and quality assurance
    2Dept.of Biotechnology
    Annamacharya college of pharmacy, Rajampet
    surekhapharmacy@gmail.com

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