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  • CHRONIC MUCUS HYPERSECRETION AND CHRONIC OBSTRUCTIVE LUNG DISEASE THE MOST DISABLING HEALTH EFFECTS OF TOBACCO

    About Authors:
    Chinedu Enegide*, Mr. Kennedy I. Amagon
    Department of Science Lab. Tech.
    (Physiology/Pharmacology Tech.),
    University of Jos, Nigeria
    chinex.snow@gmail.com

    Abstact
    The use of tobacco have been in existence for long and have also been widely abused. Tobacco is now the leading cause of preventable death in the world today. An estimate of more than 5 million deaths  are recorded world-wide, yearly. Prediction also shows that deaths caused by tobacco may escalate to about 8 million by 2030. Statistics have shown that one out of every five deaths annually is caused by cigarette smoking. This statistics reveals about 440,000 smoking-related deaths yearly, and about 49,000 of these deaths are due to passive smoking. Both voluntary and involuntary (passive) smokers are at risk of the effects of tobacco. The effects of tobacco includes increased stress, alteration of brain cells chemistry, alteration of lipid profile, facilitation of atherosclerosis, increase in heart-rate and blood pressure, gastroesophageal reflux disease, peptic ulcer disease, micro-nutrient disorders, oxidtive damage, bronchospasm, chronic mucus hypersecretion and chronic obstructive lung disease. But however, chronic mucus hypersecretion and chronic obstructive lung disease stands out to be the most disabling effect of tobacco. As these effects are known to reduce one's physical performance, breathing capacity as well as fitness (both present and future). It is therefore advised that better measures for controlling tobacco usage especially in public places should be employed. As this will help to reduce the treat it currently posess on public health (especially the high rate of chronic mucus hypersecretion and chronic obstructive lung disease occurrence caused by tobacco).

  • METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS DETECTION BY PCR

    About Author:
    Mariz Sintaha
    Lecturer,
    School of Life Sciences
    Independent University, Bangladesh
    sintu.bmb@gmail.com

  • ROLE OF ANTIOXIDANT IN CANCER TREATMENT: A REVIEW

    About Authors:
    Dhakar Mukesh*, M. Jeevan, Kumar Neeraj, Dashora Ashok
    Geetanjali Institute of Pharmacy,
    (Department of Pharmaceutical Chemistry.)
    AirPort Road, Dabok, Udaipur (Rajasthan)- 313022
    *dhakarmukesh03@yahoo.com

  • PROSTAGLANDIN A USEFUL STRATEGY FOR NEW DRUG DEVELOPMENT: A REVIEW

    ABOUT AUTHORS:
    S.P.Sethy*1, P.Mishra2, T.Sameena1, P.Patil1, K.Shailaja1
    *1Department Of Pharmaceutical Chemistry, Sushrut Institute of pharmacy
    Taddanpally (V), Pulkal (M), Medak Dist-502273
    2Department Of Pharmacology.
    Malla Reddy College Of Pharmacy, Maisamaguga,
    Dhulapalli, Secunderabad-14

  • EVALUATION OF ANTIOXIDANT ACTIVITY OF FICUS GLOMERATA FRUIT

    About Authors:
    Gurvinder Pal Singh
    Senior Lecturer, Department of Pharmacognosy,
    Adesh Polytechnic College, Sri Muktsar Sahib, Punjab
    gp_singh352000@yahoo.com

  • NATURAL POLYMERS USED IN FLOATING DRUG DELIVERY SYSTEM

    ABOUT AUTHOR:
    Jeevan Menaria*, Rahul Kumar Garg, Dr. Ashok Dashora
    Geetanjali Institute Of Pharmacy,
    Udaipur 313001
    *jeevanmenaria@gmail.com

  • GLIPTINS: BETTER APPROACH FOR TYPE 2 DIABETES

    About Author:
    Parul Lal
    Product Manager
    Sapient Laboratories PVT. LTD
    parullal2011@gmail.com

  • SPECTROPHOTOMETRIC DETERMINATION OF ROSUVASTATIN CALCIUM IN MARKETED FORMULATION

    About Authors
    Narsinh N. Potdar*, Pranita P. Kore, Rishikesh V. Antre
    Department of Pharmaceutical Chemistry,
    JSPM’s Charak College of Pharmacy and Research, Wagholi,
    Pune-Nagar Road, Pune-412 207 (India)

    *narsinh_potdar@rediffmail.com

    Abstract
    Three new simple, economic spectrophotometric methods were developed for quantitative estimation of Rosuvastatin Calcium in bulk formulation. First method includes determination of Rosuvastatin Calcium at absorption maxima 252 nm, second method applied was area under curve for analysis of Rosuvastatin Calcium in the wavelength range of 247-257 nm and third method was first order derivative. Beer law obeyed in the concentration range of 5-35 μg/ml for all three methods. The correlation coefficients were found to be 0.974, 0.982 and 0.982by absorption maxima, area under curve and first order derivative spectra. Results of analysis were validated statistically and by performing recovery studies. The mean percent recoveries were found satisfactory for all three methods. The percentage label claim was found in the range of 100.28% to 101.01% .The proposed method was validated statistically and recovery studies.

  • TOXICOLOGICAL ASPECTS OF ARIPIPRAZOLE- A NEW ANTIPSYCHOTIC DRUG: REVIEW ARTICLE

    About Author:
    Renuka G. Hade
    Quality Assurance Department, Wockhardt Limited,
    Aurangabad (431210), M.S.
    renukahade@gmail.com

    Abstract:
    Aripiprazole is a new antipsychotic agent. There is presently no evidence to suggest that it is more effective than existing antipsychotics in the treatment of schizophrenia but it offers prescribers another treatment option for this illness. Its efficacy in treatment-resistant schizophrenia is not established; for these patients clozapine is generally considered the drug of choice.
    Aripiprazole is a widely used antipsychotic drug supplied in various dosage forms of Aripiprazole Tablets, Aripiprazole Orodispersible tablets and Aripiprazole Oral solution. These formulations are approved by United States Food and Drug Administartion (USFDA) and European Medicinal Agency (EMA) under the brand name Abilify®, manufactured by Otsuka Pharmaceuticals Limited.1
    Based upon the current market demands of the Aripiprazole worldwide, a complete review of the non-clinical (Animal) safety (toxicological studies), is of considerable importance.

  • MATERNAL AND FETAL OUTCOMES IN PREGNANCY INDUCED HYPERTENSION-A RETROSPECTIVE, OPEN LABELED STUDY

    About Authors:
    *Jayalakshmi Ramanna,
    Dr. Ravishankar Gunturu
    M.Sc., CCRP,
    BDS, M.sc., CCRP
    jaya14lak@yahoo.com

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