About Authors: Chaudhari Rahul B.
Department of Pharmaceutical Technology,
University Institute of Chemical Technology (UICT),
North Maharashtra University,
Jalgaon - 425 001 (M.S.) India rahul88chaudhari@gmail.com
ABOUT AUTHORS: Bhatt Preeti *, Gnanaranjan. G , kothiyal Preeti
Department of pharmaceutics,
Shri Guru Ram Rai Institute Of Pharmacy,
Dehradun-248001, India *preetibhatt03@gmail.com
ABOUT AUTHOR: Akshay Rajgaria
Kanak Manjari Institute of Pharmaceutical Sciences akshaykrish2007@gmail.com
ABSTRACT:
Progeria is a rare and peculiar combination of dwarfism and premature ageing. The incidence is one in several million births. It occurs sporadically and is probably an autosomal recessive syndrome. Though the clinical presentation is usually typical, conventional radiological and biochemical investigations help in confirming the diagnosis.
ABOUT AUTHORS: P.Monica1*, DR.Nikunjal Mishra2 1Yalamarthy college of pharmacy, Visakhapatnam, A.P 2HOD. Department of pharmacology Yalamarthy College of pharmacy, Visakhapatnam, A.P *monica_reddy2308@yahoo.com
About Author: Alex Martin*
Department of Pharmaceutical Chemistry,
St. Joseph’s College of Pharmacy, Kerala University of Health Sciences,
Cherthala-688524 (Kerala), India. aalexmartin@rediffmail.com
About Authors: Shanky Bhat*, Kushal Kandhari
M Phil-Ph.D Scholar
School of Environment and Sustainable Development
Central University of Gujarat,
Sector 30, Gandhinagar, Gujarat 382030 bhatsiya@gmail.com
ABOUT AUTHORS: Dewangan A*, Tomar B, Dr.Mehta P.
Department of Pharmaceutics,
Lakshmi Narain College of Pharmacy, Bhopal-462021 devakash.1850@rediffmail.com
ABSTRACT:
Immediate release tablets prepared by wet granulation method containing drug by using superdisintegrants like Crosscarmellose, Sodium starch glycolate in different concentrations i.e 4.5% and 3% and the selected superdisintegrants were used along with different diluents like microcrystalline cellulose and their combinations. Comparative evaluation of Terbinafine Hydrochloride tablets by wet granulation method as its formulations rapidly disintegrates in the stomach. The in-vitro percentage drug release from the formulation F-8 prepared by wet granulation compression containing Microcrystalline cellulose at concentration of 5% was found to be 99.67% drug release.