Articles

{ DOWNLOAD AS PDF }

ABOUT AUTHORS
Nayan Jain*, Ashutosh Biswas, Kratika Vivek Daniel
Mandsaur Institute of pharmacy,
Mandsaur, MP, India
*nayanofficial499@gmail.com

ABSTRACT
Today the world has suffered to the Zika virus is a flavivirous related to yellow fever, dengue, West Nile and Japanese encephalis virus. Zika virus causes acute, serious illness which is often fatal if it is not treated. Its name comes from the Zika forest of Uganda. Zika is a mosquito born disease. Zika virus disease is caused by a virus transmitted primarily by Aedes mosquitoes. People with Zika virus disease can have symptoms including mild fever, skin rash, conjunctivitis, muscle and joint pain, malaise or headache. These symptoms normally last for 2-7 days. There is scientific consensus that Zika virus is a cause of microcephaly and Guillain-Barré syndrome. Links to other neurological complications are also being investigated. Neither an effective treatment nor a vaccine is available for Zika virus; therefore, the public health response primarily focuses on preventing infection, particularly in pregnant women. These article also covers from where the zika was firstly introduced or its history, its transmissions, causes, diagnosis, treatment and some current affairs.

{ DOWNLOAD AS PDF }

ABOUT AUTHORS
Dr. M. Manasa Rekha1*, Dr.M.Manasa², C.Reddy Kumari^2
1*,² Doctor of pharmacy, Department of Pharmacy Practice,
Annamacharya college of Pharmacy,
Rajampet, Kadapa, Andhra Pradesh, India.
*manasarekharoyal@gmail.com

ABSTRACT:
Poly-Cystic Ovary Syndrome (PCOS) is characterized by multiple small ovarian cysts, obesity, hypertension, diabetes, insulin resistance, and Hirsutism. The Study Aims to assess the role of Doctor Of Pharmacy in identification of risk factors in developing poly cystic ovarian syndrome among teenagers and minimizing them by life style modifications through advanced Patient counseling.The Main Objective of the present study is to prevent the following: To prevent the complications of PCOS who are suffering with PCOS in early of their age. To prevent the occurrence of PCOS to early females who are nearer for its occurrence. To minimize the symptoms and to improve the quality of life of females suffering with PCOS. Study Design: It is a observational and interventional study. Study Period: The Present study was conducted for a period of 6 months from January 2nd  2017 to July 31st 2017.Study site : The Present study was conducted in BAHUDHA WOMENS HOSTEL affiliated to Annamacharya college of Pharmacy, Rajampet, Kadapa, Andhra Pradesh, India. In The Present Study Out of total 600 women   530 enrolled to participate in the present study. After the collection of information by PCOS  self assessment forms the scoring is given as 271 with scoring >5 with percentile 51.1320 are with Chance for getting PCOS, 159 with scoring > 10with percentile 30.01 are with high Chance for getting PCOS, 100 with scoring  <5with percentile 18.8679 are Unpredictable to PCOS. The present study concludes that Doctor Of Pharmacy is very helpful in assessing the risk factors responsible in developing PCOS and also minimizing them by life style modifications through advanced patient counseling.

{ DOWNLOAD AS PDF }

ABOUT AUTHORS
Nabadoy Roy*, Suprodip Mandal, Beduin Mahanti, Sandipan Dasgupta*
Division of Pharmacology, Department of Pharmacy,
Bharat Technology, Uluberia, Howrah 711316,
*n.roy.santoshpur@gmail.com

ABSTRACT
Objective:  The aim of this present study is to evaluate the activity of green tea extracted in different solvents on different microorganism such as on Staphylococcus aureus ATCC 6538, Escherichia coli ATCC 8739, Salmonella abony NCTC 6017, Pseudomonas aeruginosa ATCC 9027, Candida albicans ATCC 10231, Esteritia coli mutant NCIM 2567, Bacillus subtilis ATCC 6633 &Lactobacillus lichmani ATCC 7830.
Method:  Zone of inhibition of aqueous, methanolic and ethanolic extracts were measured and compared by using cup plate method. 5µg, 10µg, 15µg & 20µg concentration of the extract were used. MIC (Minimum inhibitory concentration)& MBC (Minimum bactericidal concentration ) were observed with the concentrations of 100µg, 75µg, 50µg & 25µg.
Result: Result of zone of inhibition shows that aquous extract at the concentration of 20µg/ml is most effective to inhibit Escherichia coli growth compare to standard.Also minimum inhibitory concentration (MIC) & minimum bactericidal concentration (MBC) result suggest that aquous extract is more effective than ethanolic and methanolic extract to inhibit the growth of both Escherichia coli &Escherichia coli mutant.
Conclusion: Significant antimicrobial activity has been shown by all extracts against Escherichia coli but other microorganism inhibition is not so significant compare to Escherichia coli. Methanolic and ethanolic extract has shown little antimicrobial activity against all microorganisms as compared to the aqueous extract.

{ DOWNLOAD AS PDF }

ABOUT AUTHORS
Devender Sharma1*, Ameya Lanjewar2
¹Department of Pharmaceutics, Hi-Tech College of Pharmacy, Chandrapur India
²Department of Pharmaceutics, Kamala Nehru College of Pharmacy, Butibori Nagpur India
*sdevender350@gmail.com

ABSTRACT
Ibuprofen largely used in various disorders  treatment likely to be  rheumatoid arthritis, osteoarthritis and other musculoskeletal disorders, especially where pain is more prominent than inflammation. Ibuprofen is used as a simple analgesic, antipyretic and it is particularly effective in dysmenorrheal. By the process of Moisture activated dry granulation, Ibuprofen tablets prepared but these method prepared tablets do not give better drug content, drug release. So formulation optimize by full factorial i.e. change in various polymer concentration like SSG and Povidone at three different levels. Ibuprofen tablets manufactured by moisture activated dry granulation method with optimization show better drug release, drug stability in comparison of marketed preparation. Due to optimization, Ibuprofen tablets which manufactured by moisture activated dry granulation method have very low cost in comparison of marketed preparation. The main objective of this research work water poorly soluble drug like ibuprofen tablet manufactured by moisture activated dry granulation by optimize process gives better drug release, manufacture cost also less other than marketed tablets.

{ DOWNLOAD AS PDF }

ABOUT AUTHOR
K.GOPALASATHEESKUMAR¹*, T.BOOPATHI^1
1KMCH college of Pharmacy, Kovai Estate,
Kalapatti Road, Coimbatore-641048, Tamil Nadu, India
gskpungai@gmail.com

ABSTRACT
The using of natural plants in treatment purposes are the nowadays most familiar than synthetic products because synthetic drugs can cause many of the side effects and the adverse effect. The Tecoma stansare one of the plants which are available in most of the tropical countries. In this plant is already used in the traditional medicine in some of the countries like India, Pakistan, etc., this plant belongs to the family of Bignoniaceae. This plant is having the many of the active chemical constituents and pharmacological effects. Many of the researchers are studied the pharmacological screening and the current research is going in that plant. The aim of this review was the updated research collections of this plant for its pharmacological screening. The review the  on various researchers like pharmacognostical study and the in vitro and in vivo screening of various parts of Tecoma stans.In this review was concluded that the various parts of the plants are having various pharmacological actions like anti-inflammatory, analgesic, anticancer cardio-protective effect, genotoxic, cytotoxicity, wound healing, anti‐hyperglycemic, protect CNS, gastric ulcer healing, antiproliferative, antioxidant, anti-microbial, hemolytic activity, anti-lipoxygenase and acetyl-cholinesterase inhibitory activities. And this review was used to develop the future research on this plant.

[adsense:336x280:8701650588]

{ DOWNLOAD AS PDF }

ABOUT AUTHOR
Dr. Vishwas B. Chavan
Aditya Jyot Hospital & Foundation
vishwaschavan2003@yahoo.co.in

Cancer is a leading cause of morbidity and mortality in the world today. According to one study, there were 14.1 million new cases of cancer and 8.2 million cancer-related deaths worldwide in 2012. The most commonly diagnosed cancers were lung (1.82 million), breast (1.67 million), and colorectal (1.36 million). The most common cancer deaths are due to lung cancer (1.6 million deaths), liver cancer (745,000 deaths), and stomach cancer (723,000 deaths) (Ferlay, J. et al, 2015).

{ DOWNLOAD AS PDF }

ABOUT AUTHOR
Devender Sharma*
Hi – Tech college of pharmacy, Chandrapur, Maharashtra (India)
*sdevender350@gmail.com

ABSTRACT
Transdermal drug delivery carried out a promising carrier in the transport of drugs to get direct access across the skin deep into the systemic circulation. Transdermal drug delivery have a number of advantages including improved patient compliance, sustained release, avoidance of gastric irritation, as well as elimination of pre-systemic first-pass effect. It gives attraction to many researchers due to various biomedical advantages. Due to the limitation of oral drug delivery system and the pain related with the use of needles in case of injections, drug delivery research has tremendously oriented towards the transdermal route. Delivery of drugs via transdermal route has proved to be the convenient route for various clinical implications. The objective of the present review is to focus on newly innovations in transdermal drug delivery systems which can create a platform for the research and development of pharmaceutical drug dosage form for efficient transdermal delivery. In this review, we tell about different types of microneedles are described and their methods of fabrication. Microneedles can be fabricated in different forms like hollow, solid, and dissolving. There are also hydrogel-forming microneedles.  In relation to hydrogel-forming microneedles, special attention, these are innovative microneedles which does not contain drugs but imbibe interstitial fluid to form continuous conduits between dermal microcirculation and an attached patch-type reservoir. Regulatory authorities approved several microneedles for clinical uses are also examined. The last part of this review discusses concerns and challenges regarding microneedles use.

{ DOWNLOAD AS PDF }

ABOUT AUTHORS
Devender M. Sharma*1, Satish B. Kosalge1, Swati N. Lade1
Hi – Tech college of pharmacy, Chandrapur (M.S.)
*sdevender350@gmail.com

ABSTRACT
Tablets are unit solid dosage form of medicament which largely used to compare other dosage form of medicaments. In tablet manufacturing, wet granulation and dry granulation methods largely used as compare to MADG process. In wet granulation and dry granulation methods various steps has been carried out like dispensing and shifting, dry mixing, granulation, pre-drying, shifting, premixing, lubrication and compression. But in MADG process, escape various steps like slugging, pre- drying, shifting, and drying. Hereby in MADG process save energy, cost of product and time also. The main object of review is hereby moisture activated dry granulation process very beneficial in case of water insoluble drug and water poorly soluble drug other than granulation method like wet granulation. Another objective of review how moisture activated dry granulation process carried out and given various advantages over the other granulation method. In water insoluble drug case MADG process largely used and very useful method for pharmaceutical industries.

{ DOWNLOAD AS PDF }

ABOUT AUTHORS
*R.Karthikeyan, E.Meghana, N.Gowthami, MD.Shajiya sultana, B.Mahesh reddy, SK.Magbul Johny, P.Srinivasa Babu
Department of Pharmacognosy, Vignan Pharmacy College, Vadlamudi – 522213.A.P
*rkcognosy@gmail.com

ABSTRACT
The synthesis of nanostructure substances, specifically metal nanoparticles, has accrued utmost concern over the last decade owing to their particular properties that cause them to applicable in distinctive fields of technology era. The biological technique of nanoparticle synthesis is a relatively easy, reasonably-priced, and environmental friendly approaches than the conventional chemical technique of synthesis and accordingly profits a top hand. The bio mineralization of nanoparticles in protein cages is one among such biological approaches used inside the era of nanoparticles. In this review we attempted to explore different techniques of synthesis of nanoparticles and its characterization. Further this review extended the usage of such nanoparticle in different fields.

[adsense:336x280:8701650588]