• PharmaTutor
    16 May 2013

    MICROSPHERE AS DRUG CARRIER: A REVIEW

    ABOUT AUTHORS:
    Madhuri D. Ghadage*1, Gajanan H. Banapure2
    1Department of Pharmaceutics, SMBT College of Pharmacy, Dhamangaon, Nashik
    2H. R. Patel Institute of Pharmaceutical Education and Research, Shirpur Dhule
    *maadhuri.ghadge@gmail.com

    ABSTRACT
    The controlled release of drugs in slow and sustained manner is one of the major challenges in drug delivery system. Targeting of drug to the particular site is an important aspect of drug delivery system. Carrier technology offers an intelligent approach for drug delivery by coupling the drug to a carrier particle such as microsphere which modulates the release and absorption characteristics of the drug. These delivery systems offer numerous advantages over the conventional dosage forms including improved efficacy, reduced toxicity, and improved patient compliance. Microspheres received much attention not only for prolonged release, but also for targeting of anticancer drugs. In future microspheres will find the central place in novel drug delivery, particularly in diseased cell sorting, diagnostics, genetic materials, targeted and effective drug delivery. The current aim of this review is to study various aspects of the microparticulates drug delivery system including method of formulation, evaluation & characterization.

  • TETRACYCLINE- FORGOTTEN ANTIBIOTICS
    16 May 2013
    TETRACYCLINE- FORGOTTEN ANTIBIOTICS

    Presently, the name tetracycline refers to a number of antibiotics of either natural, or semi-synthetic origin, derived from a system of four linearly annelated six-membered rings (1,4,4a,5,5a,6,11,12a-octahydronaphthacene) with a characteristic arrangement of double bonds. The tetracycline molecule possesses five asymmetric centers: C-4, -4a, -5a, -6, and -12a.

  • DETERMINATION OF EFFECT OF DIETHYL MALEATE ON iNOS EXPRESSION AND CELL VIABILITY
    15 May 2013
    DETERMINATION OF EFFECT OF DIETHYL MALEATE ON iNOS EXPRESSION AND CELL VIABILITY

    About Authors:
    *Ravi Patel, Dr Shori Thakur
    Pharmacy and Pharmaceutical Science Department,
    University of Hertfordshire, Hatfield
    AL10 9AB, United Kingdom
    Ravi_pharmacology@yahoo.com, Ravipatel12345@gmail.com

  • PHARMACOVIGILANCE SYSTEM IN WORLD
    15 May 2013
    PHARMACOVIGILANCE SYSTEM IN WORLD

    ABOUT AUTHOR:
    Vishwa Deepak kumar
    Departement of Pharmacy,
    IEC group of institution,
    Greater Noida (U.P), Pin- 201301
    vdkumar.iec@gmail.com

  • VISIBLE RESIDUE LIMIT- SCOPE OF IMPROVEMENT
    14 May 2013
    VISIBLE RESIDUE LIMIT- SCOPE OF IMPROVEMENT

    ABOUT AUTHOR:
    Arsh Chanana
    Department of Pharmaceutics,
    Seth G.L. Bihani S.D. College of Technical Education Sri Ganganagar.
    arshchanana@ymail.com

  • A REVIEW ON METFORMIN AND ITS LIFE THREATENING ADVERSE EFFECT
    14 May 2013
    A REVIEW ON METFORMIN AND ITS LIFE THREATENING ADVERSE EFFECT

    ABOUT AUTHOR:
    Amitava Sinha Ray
    Department of Pharmacy,
    Bengal School of Technology
    West Bengal University of Technology, West Bengal
    a.amitava.s@gmail.com

  • HERBAL TREATMENT AND RHEUMATOID ARTHRITIS: AN OVERVIEW
    13 May 2013
    HERBAL TREATMENT AND RHEUMATOID ARTHRITIS: AN OVERVIEW

    About Authors:
    Prabhakar Sharma*1, Prakash Pandey1, Sunil Roshan1, Ashish Garg2, Vikas Pandey3, Anil Pasi4
    1Department of Pharmacognosy, GRKIST (Pharmacy), Jabalpur, M.P.
    2Department of Pharmaceutics, GRKIST (Pharmacy), Jabalpur, M.P.
    3Department of chemistry, RDVV, Jabalpur, M.P.

  • CONSIDERATIONS FOR BIOANALYTICAL METHOD DEVELOPMENT AND VALIDATION BY USING LC-MS/MS-A REVIEW
    13 May 2013
    CONSIDERATIONS FOR BIOANALYTICAL METHOD DEVELOPMENT AND VALIDATION BY USING LC-MS/MS-A REVIEW

    ABOUT AUTHOR:
    Bhimavarapu Ramya Reddy
    Department of Pharmaceutical Analysis,
    A.M Reddy Memorial College of Pharmacy, Narasaraopet,
    Guntur, Andhra Pradesh, India.
    ramyareddy.bh@gmail.com

  • A REVIEW : APPROACH IN DENTAL DRUG DELIVERY SYSTEM
    12 May 2013
    A REVIEW : APPROACH IN DENTAL DRUG DELIVERY SYSTEM

    ABOUT AUTHORS:
    Badola Ashutosh,* Nishu Sharma
    Shri Guru Ram Rai Institute of Technology & Science ( SGRRITS ),
    Dehradun 248001, Uttarakhand , India
    *ashutosh.badolam.pharma@gmail.com

    ABSTRACT:
    Controlled release local drug delivery systems offer advantages compared to systemic dosage forms for periodontitis. The objective of this research was to design and evaluate sustained release dental films containing drug in a non-biodegradable polymer for targeted delivery of the drug. The polymer ethyl cellulose was used in the formulation of dental films. The dental film was then evaluated for various parameters like thickness, folding endurance, and weight variation, and content uniformity, in vitro and in vivo study. Drug release profile of the dental film showed that the film exerted an initial burst release followed by a sustained release of the drug and the drug release was well above the minimum inhibitory concentration throughout the time of study. The release data obtained were subjected for release kinetics study. The study suggested that the non-biodegradable based dental film is a potential local drug delivery device for the treatment of periodontitis.

  • THE HUNT FOR COUNTERFIET AND INFERIOR DRUGS
    12 May 2013
    THE HUNT FOR COUNTERFIET AND INFERIOR DRUGS

    ABOUT AUTHOR
    Kunal Roy
    NSHM Group of Institutions Knowledge campus,
    Department of Pharmaceutical Analysis & Quality Assurance
    Kolkata-700053
    kunal.roy17@gmail.com

    ABSTRACT:
    Counterfeit Culture is a one of the most important and dangerous crime in the world of drugs and its related products  and  explores the dangerous and sometimes deadly world of fake, fraudulent, and faux products. The pharmaceutical  industry has a has history of peddled knock-off  dosage forms, medical devices   but during the last 15 years, it has mushroomed into a global phenomenon.
    The range of counterfeit goods now being produced includes pharmaceuticals. The traffic in counterfeit goods is now estimated at a staggering $350 billion representing nearly 10% of all global trade. This illicit and highly profitable criminal enterprise continues to grow unabated and has been linked to organized crime syndicates around the world.

    [adsense:336x280:8701650588]

Subscribe to Articles