Review Articles

About Author
AKASH GUPTA 
M.Pharm (pharmaceutics)
Kota college of pharmacy,
Ranpur, Kota

ABSTRACT
Comorbid depression and anxiety disorders occur in up to 25% of general practice patients. About 85% of patients with depression have significant anxiety, and 90% of patients with anxiety disorder have depression.  Both the depression disorder and the specific anxiety disorder require appropriate treatment. Psychological therapies, such as cognitive behaviour therapy, and antidepressants, occasionally augmented with antipsychotics, have proven benefit for treating both depression and anxiety. Depression and anxiety are the most common psychiatric conditions seen in the general medical setting, affecting millions of individuals in the word. The treatments for depression and anxiety are multiple and have varying degrees of effectiveness. Physical activity has been shown to be associated with decreased symptoms of depression and anxiety. Depression is a multicausal disorder and has been associated with the risk to develop cancer, dementia, diabetes, epilepsy and stroke. mainly this article aim  how to deal and treatment for depression and anxiety.

ABOUT AUTHORES 
AKASH GUPTA  M.Pharm (pharmaceutics)
akashav88@gmail.com
Kota college of pharmacy,ranpur, kota - 325003

ABSTRACT
The purpose of writing this review on floating drug delivery systems (FDDS) was to The recent developments of FDDS including the physiological and formulation variables affecting gastric retention, approaches to design single-unit and multiple-unit floating systems, and their classification and formulation aspects are covered in detail. Prolonged gastric retention improves bioavalibility, reduce drug waste, and improve solubility for drugs that are less soluble in a high ph environment. It has applications also for local drug delivery to the stomach and proximal small intestines.

ABOUT AUTHORS
Swarupananda Mukherjee*, Sohini Bera, Moumoyee Chakraborty 
NSHM Knowledge Campus, Kolkata – Group of Institutions,
Department of Pharmaceutical Technology, 124, B L Saha Road,
Kolkata, India
* Swarupananda.mukherjee@nshm.com

ABSTRACT :
Corona viruses are a family of enveloped, positive stranded, single stranded RNA viruses. This corona virus family consists of pathogens of several human and animal species including SARS-CoV, NovelCOVID-19 but now referred to as SARS-CoV-2 by the Study Group. SARS-CoV-2 International Committee on Virus Taxonomy Corona Virus belongs to the genus Beta corona virus family Corona viridae. The virus has spread globally since its introduction, causing millions of deaths and critically affecting our health services and economies. There are currently no approved preventive drugs or treatment methods available. Hundreds of clinical trials were performed to find treatments that were successful. Here we are reviewing currently reported clinical studies for COVID-19 treatment and prevention to give an overview and perspective into the global response.

AUTHORS :
Gouranga Sundar Roy ¹*, Sangita Biswas² 
Department of Pharmacy, Bengal School of Technology
(A College of Pharmacy),
Sugandha, Delhi Road Near Chuchura, Hooghly - 712102,
West Bengal, India

ABSTRACT:
Scott Craniodigital syndrome is a situation that has best been found in families. The manifestations consist of uncommon head shape, boom and developmental delay, and mild webbing between the arms and toes. Less than 10 cases have been described within the literature so far. Clinical description strange dermatoglyphic patterns, boom retardation and brachycephalic have additionally been reported. Scott Craniodigital Syndrome with Mental Retardation is a very uncommon inherited disorder this is fully expressed in male best. Mental retardation (MR) is a widely used term but a contentious one. There is still a quest for appropriate terminology that doesn't companion with negative perception of affected character ad but is correct in phrases of nosology. Also debatable is the most appropriate methodology. Scott Craniodigital syndrome is believed to be inherited as an X-connected recessive genetic trait, based totally on the presence of the circumstance in males most effective. Carrier ladies have very moderate manifestation. The motion disorder related with can be managed by way of pharmacological treatment of thru physical remedy and occupational therapy to reduce disability. Some drug remedy which have been used to control.

AUTHORS :
^*Tinku Kumar Singh¹, Satish Kumar¹, Purna Tiwari^2
1 Indchemie health Specialities Pvt. Ltd
² Alkem health science Ltd
tinku20190@gmail.com
 

ABSTRACT : The World Health Organization (WHO) has declared the corona virus disease 2019 (COVID-19) a pandemic. In January 2020, a previously unknown new virus was identified subsequently named the 2019 novel corona virus, and samples obtained from cases and analysis of the virus’ genetics indicated that this was the cause of the outbreak. Corona viruses are a group of related viruses that cause diseases in mammals and birds. The COVID-19 virus spreads primarily through droplets of saliva or discharge from the nose when an infected person coughs or sneezes. Corona viruses are large pleomorphic spherical particles with bulbous surface projections. Isolation remains the most effective measure for containment of COVID-19. Moreover unnecessary administration of antibiotics should also be avoided. Critically ill patients require high flow oxygen, extracorporeal membrane oxygenation (ECMO), glucocorticoid therapy, and convalescent plasma. Therapeutically, aerosol administration of alpha-interferon (5 million units twice daily), chloroquine phosphate, and lopinavir/ritonavir have been suggested.

ABOUT AUTHORS
Navneet Kaur¹, Latika Khosla^2
1Department of Biotechnology, CT Institute of Pharmaceutical Sciences, Shahpur, Jalandhar-144001, Punjab.
²Department of Biotechnology, Kanya Maha Vidyalaya, Jalandhar-144004, Punjab

ABSTRACT
Diabetic nephropathy (DN) is defined as a progressive pathological condition of the kidney caused by angiopathy of glomerular capillaries. The angiopathy of these capillaries is characterized by a progressive loss of glomerular filtration surface areas and capillary volume. DN is the leading cause of end-stage renal disease, and a major contributing factor to morbidity and mortality of diabetic patients throughout the world.

ABOUT AUTHORS
Mudasir Maqbool¹*, Mohmad Amin Dar¹, Shafiqa Rasool¹, Rabiah Bashir1, Misba Khan ^2
1Department of Pharmaceutical Sciences,
University of Kashmir, Hazratbal Srinagar, Jammu and Kashmir, India
²Mader-E-Meharban Institute of Nursing Sciences and Research,
Jammu And Kashmir, India

ABSTRACT
The maintenance of a healthy liver is vital to overall health of the human beings. Since the liver is involved in almost all biochemical processes and there are many different diseases that will affect it. The liver is often abused by environmental toxins, which are eating habits, alcohol and overdose of certain drugs which can damage and weaken the liver and eventually lead to many diseases. Medicinal herbs are significant source of hepatoprotective drugs. Mono and poly-herbal preparations have been used in various liver disorders. According to one estimate, more than 700 mono and poly-herbal preparations in the form of decoction, tincture, tablets and capsules from more than 100 plants are in clinical use. From the literature review near about 178 medicinal plants are reported to possess a hepatoprotective activity. A drug having beneficial effect on the liver is known as hepatoprotective drug. On the other hand, drugs having toxic effect on the liver are better known as hepatotoxic drugs. The most commonly used parameters to assess the hepatoprotective activity are morphological e.g. Liver weight and volume, biochemical estimations, such as measurement of transaminase activity, SGPT, SCOT, alkaline phosphatase, serum bilirubin, total serum proteins, albumin, globulin and prothrombin time, functional parameters, pentobarbitone and hexobarbitone sleeping time and finally histopathological study regarding presence of necrosis, fatty degeneration and cirrhosis. In this review, we will briefly discuss hepatotoxicity and hepatoprotective agents.

ABOUT AUTHORS
Navjeet Singh*, Mrinal and Rubal Thakur
Dreamz College of Pharmacy, Khilra, Sundernagar, Himachal Pradesh, India

ABSTRACT: Medicinal plants and derived medicine are widely used in traditional culture all over the world and they are becoming increasingly popular in modern society as natural alternatives to synthetic chemicals. Tagetes erecta Linn Known as “genda phool” (Marigold) belong to the family Astraceae, native to Mexico, Central America, Bolivia and Colombia. All parts of this plant used for medicinal purposes. It contained wide range of chemical constituents thiophenes, flavanoids, cartenoids, triterpenoids, oxycaroteniod and xanthophylls. This review article focus on the pharmacological actions like antibacterial, antifungal, antioxidant, hepatoprotective activity, wound healing property, cytotoxic and insecticidal activities. This review is a step to open insight for therapeutic efficacy of Tagetes erecta.

ABOUT AUTHORS
Pomila*; Anjali Sidhu
Department of chemistry,
Punjab Agriculture University,
Ludhiana, Punjab, India

ABSTRACT
The current review frameworks different approaches of synthesis and various biological activities of allyl sulfides. The food-based natural products (allyl sulfides) are major organo-sulfur constituent of garlic had been studied extensively due to their moderate toxicity accompanied by number of biological applications such as anti-cancer, anti-microbial, antibiotic, antimutagenic and detoxification etc. The broad-spectrum application of allyl sulfides inspires us to do advance research on it.