Uttar Pradesh

PERMEATION ENHANCERS - FULL INTRODUCTION: A REVIEW

ABOUT AUTHORS:
DEVENDRA SINGH1*, PANKAJ KUMAR SHARMA1, ROOHI KESHARWANI2, Dr. UDAI VIR SINGH SARA1

1Raj kumar goel institute of technology, Delhi-Meerut Road, Ghaziabad, India
2Chandra shekhar singh college of pharmacy, Kaushambi, Uttar Pradesh, India.

* devendrasingh.pisces@gmail.com

ABSTRACT:
Oral administration still dominates drug therapy and more than 60 % of marketed drugs are oral products. This type of drug administration is preferred due to its convenience, high patient compliance, less stringent production conditions and lower costs. Unfortunately, this traditional drug delivery method has its limitations, due to gastrointestinal permeability, metabolism and elimination of drugs by the liver or gastrointestinal mucosa (first-pass effect). The main drawback of the oral route is that only those compounds that are stable in the gastrointestinal tract can be administered in this way. For this reason, the oral route has been used for mainly non-peptide drugs. Delivery of a drug by oral route is predominantly restricted by pre-systemic degradation and poor penetration across the gut wall. The major challenge in the oral drug delivery is the development of novel dosage forms to endorse absorption of poorly permeable drugs across the intestinal epithelium. In this article we reviewed the various permeation enhancers, histology of small intestine, barriers, application, advantages, some basic permeability enhancement techniques which are useful for enhancing the permeability of poorly permeable drugs

Multiple Vacancies for M.Pharm/M.Sc as ASST DIRECTOR, RESEARCH OFFICER, ASST RESEARCH OFFICER @ CCRH

CCRH, an autonomous body under the Department of AYUSH, Ministry of Health and Family Welfare, Government of India intends to engage the following categories of personnel on contract basis for a period of 06 (six) months for Homoeopathic Pharmacopoeia Laboratory (HPL), Ghaziabad (Uttar Pradesh).

IITR invites applications for post of Project Fellow- 40 Posts

The Indian Institute of Toxicology Research (IITR), established in 1965, a constituent laboratory of Council of Scientific & Industrial Research (CSIR) engaged in the Research & Development in the areas of Environmental Toxicology, Predictive Toxicology, Health Risk Assessment, Preventive Toxicology, Inhalation Toxicology, Analytical Toxicology, and also National S&T Missions. IITR has two campuses; the main campus is located at the centre of Lucknow City and the other campus at a distance of approx.

PHARMACOVIGILANCE: THE PRESENT STATUS AND FUTURE PROSPECTS IN INDIA

About Authors:
Roohi Kesharwani1*, Devendra Singh2, Vishal Jacob1
1-Institute Of Foreign Trade And Management Lodhipur Rajput,
Delhi Road, Moradabad, India
2-Raj Kumar Goel Institute Of Technology, Delhi-Meerut Road, Ghaziabad, India
*roohi4mail@gmail.com, devendrasingh.pisces@gmail.com

ABSTRACT:
Pharmacovigilance is now accepted to be a continuous process of evaluation accompanied by steps to improve safe use of medicines which involves pharmaceutical companies, regulatory authorities, health professionals and patients. The methodologies have broadened to encompass many different types of study, with spontaneous reporting remaining the cornerstone. The concern for ADRs in highly vulnerable populations is of even greater concern.Pharmacovigilance is especially important since most of the adverse effects are reversible by modifying the dosage or omitting the offending medicine. All medicines (pharmaceuticals and vaccines) haveside effects.In a vast country like India with a population of over 1.2 Billion with vast ethnic variability, different disease prevalence patterns, practice of different systems of medicines, different socioeconomic status, it is important to have a standardized and robust pharmacovigilance and drug safety monitoring programme for the nation.  Collecting this information in a systematic manner and analyzing the data to reach a meaningful conclusion on the continued use of these medicines is the rationale to institute this program for India. In this review article various hospitals survey are done and the  survey questionnaire was analyzed question wise and their percentage value was calculated. Our study strongly suggests that there is greater need to create awareness and to promote the reporting of ADR among healthcare professionals of the country. Only such approach can greatly influence in bringing reporting culture among healthcare professionals and may improve the reporting rates of ADR in our country. Pharmacists, as doctors opined that their involvement may increase the reporting rate, have a greater role to play in the area of pharmacovigilance.

Central Institute Of Medicinal & Aromatic Plants invites Project Assistant Level-ll, Project Assistant Level-l, Research Assistant, Junior Research Fellow

Eligible and interested candidates may attend the Interview on 26/02/2013 at 9.30AM for engagement on purely temporary basis as Project Assistants of different level/ Junior Research Fellow (Projects)/ Research Assistant on contract basis in the Projects under CSIR Network Scheme, Grant-in-aid Projects and other projects sponsored by Govt. Agencies tenable at CSIR-CIMAP, Lucknow in various disciplines detailed as under.

Opening for Business Development Executive, Area Sales Manager, Sales Officer/ Territory Officer, HR Assistant, Account Assistant @ HLL Lifecare

HLL Lifecare Limited (formerly Hindustan Latex Limited) India’s leading manufacturers and marketers of Contraceptive, Health Care and Pharma products is a Mini Ratna Company under the Ministry of Health & Family Welfare, Govt. of India, with seven manufacturing units and marketing offices throughout the country.

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