A REVIEW ON CHALCONES SYNTHESIS AND THEIR BIOLOGICAL ACTIVITY
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ABOUT AUTHORS
Shipra Vermaa, Alok Kumar Srivastava*1, O.P. Pandeyb
1Department of Chemistry, Mahatma Gandhi P. G. College, Gorakhpur, U.P., India
2Department of Chemistry, D.D.U. Gorakhpur University, Gorakhpur, U.P., India
*sdevender350@gmail.com
ABSTRACT
Chalcones are a valuable molecule of medicinal importance due to presence of reactive ketoethylenic group –CO–CH=CH–, belonging to the flavonoid family. These reactive α,β-unsatutated keto function in chalcones are responsible for their biological activity. Chalcone can be synthesized by several methods using aldehydes and ketones as starting material. This review is focused about different methods of synthesis and versatile biological activity of chalcones including antimicrobial, anticancer, antioxidant, antimalarial, antituberculosis etc.