EVIDENCE-BASED MEDICINE TO PERSONALIZED MEDICINE – A PROSPECTIVE
About Author:
Pritish Dash
Institute of Bioinformatics and Applied Biotechnology (IBAB)
Bangalore, India
pr4evr@gmail.com
Abstract:
Evidence-based medicine (EBM) is the process of systematically reviewing, appraising and using clinical research findings to aid the delivery of optimum clinical care to patients. It is a method of healthcare decision-making that intends to combine the most reliable scientific information with individual expertise and patient preferences in order to offer the optimal diagnostic and therapeutic option for the patient. On the other hand, pharmacogenomics is a whole genome application that examines the single gene interactions with drugs. In recent years, the term personalized medicine has been introduced to represent an approach considering differences among individual patients. In modern medicine, the most important sources of evidence are clinical trials using epidemiological methods, and molecular biological and genetic methods characterizing individual patients.
This paper tries to review the rapid transformation of modern medicine from the ‘evidence-based medicine’ to ‘personalized and genomic medicine’.