Skip to main content

EFFECT OF TERMENALIA CATAPPA LEAF EXTRACT ON CAFETERIA INDUCED OBESITY IN RATS

{ DOWNLOAD AS PDF }

ABOUT AUTHORS
Sridatha. P*, Subbareddy.P, Sowjanya.K, Sudheer. A
Department of Pharmacology
Raghavendra Institute of Pharmaceutical Education & Research (RIPER),
Anantapuramu, Andhra Pradesh, India.

*puranamdatha@gmail.com

ABSTRACT :
Obesity is a leading cause of death worldwide, with increasing rates in adults and children.  To investigate anti-obesity effect of Termenalia catappa leaf extract on cafeteria induced obesity in rats. For anti-obesity experiment, animals were divided into five groups of six animals and housed in cages. Normal control group continued to be fed a laboratory pellet chow ad libitum. Cafeteria diet-control group received cafeteria diet in addition to the normal pellet diet. The remaining three groups were fed with cafeteria diet and NPD along with T. catappa leaf extract (200 mg/kg, p.o.), Termenalia catappa leaf extract (400 mg/kg, p.o.) and orlistat (30 mg/kg, p.o.). Treatment was continued for 4 weeks. Animals and various adipose pads were weighed and serum total cholesterol, triglyceride, LDL, VLDL and HDL-C were measured after 4 weeks of treatment. At the end various adipose tissues, aorta were removed and processed for Histopathological study.  The Termenalia catappa leaf extract -treated groups showed a significant decrease in body weight, and various adipose pad weight and serum TC, TG, LDL, VLDL and increase in HDL levels after 4 weeks treatment and decrease in the adipose tissue size and adipocyte number.  At present study, Termenalia catappa leaf extract can inhibit the development of obesity and hyperlipidemia on cafeteria induced obesity in rat. It is because of various phytoconstituents of leaf extract. But further studies are still waiting for establishing mechanism and isolation of phytoconstituents. By observing above results Termenalia catappa leaf extract can act as adjuvant in obesity treatment.

Job for M.Pharm at Advanced Centre for Treatment, Research and Education in Cancer - Salary 20000 per month

The Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) is the new state-of-the-art R&D satellite of the Tata Memorial Centre (TMC), which also includes under its umbrella the Tata Memorial Hospital (TMH), the largest cancer hospital in Asia. ACTREC has the mandate to function as a national centre for treatment, research and education in cancer. TMC is an autonomous grant-in-aid institution of the Department of Atomic Energy (DAE), Government of India. It is registered under the Societies Registration Act (1860) and the Bombay Public Trust Act (1950). Its Governing Council is headed by the Chairman, Atomic Energy Commission, Government of India.

Post : Research Fellow

Recruitment for B.Pharm, D.Pharm as Pharmacist at Tata Memorial Hospital | 03 posts

The Tata Memorial Hospital was initially commissioned by the Sir Dorabji Tata Trust on 28 February 1941 as a center with enduring value and a mission for concern for the Indian people.

Walk in interview for Guest Faculty at Pharmaceutical Science Department at Assam University

Assam University came into existence through Assam (Central) University Act, 1989 . It was  established in 1994,since then  the University is steadily becoming  an excellent centre of learning.Assam University is a teaching-cum-affiliating University. The objectives of the University are to "disseminate and advance knowledge by providing instructional and research facilities in such branches of learning as it may deem fit and by examples of its corporate life to make provisions for integrated courses in humanities, natural and physical sciences and social sciences in the educational programmes of the University; to take appropriate measure for promoting inter-disciplinary studies and research in the University; to educate and train manpower for development of the state of Assam; and to pay special attention to the improvement of the social and economic conditions and welfare of the people of that state, their intellectual, academic and cultural development."

Post : Guest faculties

Career for M.Pharm, B.Pharm as Regulatory Affairs Specialist at Medtronic

This is a question we’ve asked ourselves over and over. It’s how we at Medtronic have made hearts beat stronger and longer. It’s how we’ve pushed the limits of what technology can do in and for the body. It’s how we will continue to alleviate pain, restore health and extend life. Rising costs, an aging population, and the burden of chronic disease impact us all. And no single entity in the healthcare system can solve these challenges alone. That’s why we’re stepping forward. That’s why we’re prepared to put the full power of our technologies, services, resources — and our people — to work with new partners, in new ways, to usher in a new era in healthcare.

Post : Assoc Regulatory Affairs Spec

Job for Clinical Data Lead in Icon Clinical Research

ICON is a global provider of outsourced development services to the pharmaceutical, biotechnology and medical device industries. We specialize in the strategic development, management and analysis of programs that support Clinical Development – from compound selection to Phase I - IV clinical studies
ICON enjoys a strong reputation for quality and is focused on staff development. We make it our mission to attract the most diverse and creative minds into the business and we continually strive to provide opportunities for our people to excel, grow and build a great career. We understand that our greatest asset is the skills and talents of our people and they are truly what set us apart.

Post: CDL

Job for Master’s Degree in Life Sciences in NMHS at HNBGU

Hemvati Nandan Bahuguna Garhwal University was established as a State University vide U.P. State Government notification no. (10)/(865)/15/(75)(85)/64 dated 23 November 1973. It has a rare distinction of taking birth through a powerful popular movement during early seventies in last century. This movement symbolized the hopes and aspirations of the masses of the region of Garhwal for the development through the instrument of higher education.

Job for Senior Manager in QA & Compliance at Novartis

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

Post : Senior Manager - QA & Compliance

Applications are invited for the post of RA, SRF, JRF at Central University of Rajasthan

The Central University of Rajasthan has been established by an Act of Parliament (Act No. 25 of 2009, The Gazette of India, No. 27, published on 20th March, 2009 as a new Central University, and is fully funded by the Government of India. The President of India, His Excellency Shri Pranab Mukherjee, is the Visitor of the Central University of Rajasthan.

Post : RA / SRF / JRF – Organic Chemistry (1 post)

SIHFW invites applications Consultant under SHSRC

SIHFW invites applications from eligible candidates for the following positions on temporary/ contractual basis under SHSRC Rajasthan . The details of position and essential qualification are as under.

Post : Consultant Health Care Financing (post-1)

Opportunity for Junior Research Fellow at BHU

Banaras Hindu University ranks among the first few in the country in the field of academic and research output. This university has two campuses, 3 institutes, 16 faculties, 140 departments, 4 advanced centers and 4 interdisciplinary schools.

Job for Junior Research Fellow (JRF)/Project Assistant at University and Institute of Advanced Research

Applications are invited for Junior Research Fellow (JRF)/Project Assistant in the DST SERB-sponsored project in the Department of Chemistry, University and Institute of Advanced Research, Gandhinagar.

Post : Junior Research Fellow (JRF)/Project Assistant

Walk in interview for Research Associate at IARI

The journey of Indian Agricultural Research Institute (IARI), popularly known as Pusa Institute, began in 1905 at Pusa (Bihar) with the generous grant of 30,000 pounds from an American philanthropist, Mr. Henry Phipps. The institute was then known as Agricultural Research Institute (ARI) which functioned with five departments, namely Agriculture, Cattle Breeding, Chemistry, Economic Botany and Mycology. Bacteriology unit was added in 1907.  The name of ARI was changed to Imperial Institute of Agricultural Research in 1911 and, in 1919 it was renamed as Imperial Agricultural Research Institute. Following a devastating earth quake on 15th January 1934, the institute was shifted to Delhi on 29th July 1936. Post independence, the institute has been renamed as Indian Agricultural Research Institute (IARI)

Post : Research Associate

Job opening for M.Pharm professionals at Dr. Reddy’s Institute of Life Sciences - 32000 salary per month

The Institute of Life Sciences was conceived in the context of globalization, to foster research competence in India and to bridge the divide between academic research and the pharmaceutical & biotechnology industries. The institute was incorporated as a non-profit entity under Section 25 of the Indian companies act, facilitating operational autonomy. Construction of the ILS building comprising 44 labs and an administrative block and spanning -130,000 sq.ft. in area, began in 2004 and was completed in January 2007. The institute was inaugurated as a public-private partnership research institute on 29th January 2007, a culmination of the efforts and initiative of the Andhra Pradesh state government, Dr. Reddy's laboratories and the University of Hyderabad. The institute is located in the southeast corner of the campus of the University, one of the largest and greenest campuses in India.

Vacancy for Masters degree in Life Sciences to work in Cancer research at RGCB

The Rajiv Gandhi Centre for Biotechnology (RGCB) is a growing phenomenon. Located in Thiruvananthapuram, the capital city of Kerala, RGCB began in 1990 amongst humble surroundings as a small charitable society called the Centre for Development of Education, Science and Technology (C-DEST).

Recruitment for M.Pharm, M.Sc to work in research at DMAPR

ICAR-Directorate of Medicinal Aromatic Plants Research (ICAR-DMAPR)  is located on Ahmedabad-Mumbai rail route. The centre is 7 km away from Anand Railway station on Anand-Ahmedabad state highway towards Nadiad. Anand is well connected to all parts of the country by road, rail and Air. The nearby airports are at Vadodara (45 km) and Ahmedabad (65 km).  The Indian Council of Agricultural Research established Directorate of Medicinal & Aromatic Plants Research (formerly it was National Research Centre for Medicinal & Aromatic Plants) on November 24, 1992 in a 20.2 hectare irrigated land at Boriavi in Anand district of Gujarat.

Post : Junior Research Fellow

Career for Post graduate in professional courses to work at NIHFW | Ministry of Health and Family Welfare

The National Institute of Health and Family Welfare (NIHFW) is an Autonomous / Apex Technical Institute funded by the Ministry of Health and Family Welfare for promoting Health and Family Welfare Programmes in the country through Education & Training, Research & Evaluation, specialized services, consultancy and advisory services. This Institute has undertaken a project on "Development of Enzyme and colloidal gold based Immunoassays (ELISA and LFIA) using bridge and antigen heterology for the detection of prednisolone, Medroxyprogesterone acetate, 17 α methyltestosterone and nandrolone in biological fluids and tissues of animals". For this project, NIHFW proposes to fill the following post on contractual basis. The duration of the project is three years but the appointment will be initially for a period of one and half year which may be extended further based on performance assessment.

Post : Senior Research Fellow (SRF)

Multiple Job openings for M.Pharm, M.Sc in Etico Lifesciences Private Limited

Etico is an ethical pharmaceutical company founded in 2016 and based out in Hyderabad, India. We are specialized in development of oncological and non-oncological parenteral dosage forms development and provide product development and technology transfer solutions to innovator and generic pharmaceutical companies worldwide.

Applications are invited for ASSISTANT PROFESSOR (28 posts) in Andhra University

The Andhra Pradesh State Council of Higher Education, the first of its kind in the country, set up as per the recommendations of the National Education Policy 1986, is primarily a coordinating body between the University Grants Commission (UGC), the State Government and the Universities.

Job for Lecturer (07 posts) in Baba Farid University of Health Sciences

Baba Farid University of Health Sciences was established under an Act passed by the Legislature of the State of Punjab in July, 1998. The mission of the University is to create an intellectual, academic and physical environment, conducive to free flow of ideas and exchange of information between various faculties of the University and between this University and other Universities of Health Sciences in the country and abroad,thereby opening a window to the world for the health professionals, health planners, health managers, biomedical and social scientists and educators in health sciences of the country.

Post : Lecturer (Pharmacy)

Subscribe to