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  • AN OVERVIEW ON PATENT LAW OF INDIA AND INDONESIA

    ABOUT AUTHOR:
    Manish Mudaliar
    Department of  Quality Assurance and Regulatory Affairs,
    L J College  of   Pharmacy, Sarkhej Sanand Circle,
    S.G Highway, Ahmedabad-10
    manishmudaliar11@yahoo.com

  • ANTISENSE TECHNOLOGY: MAKING GOOD SENSE FOR CANCER TREATMENT

    About Author:
    Vivek P. Chavda
    Department of Pharmaceutics, B.K. Mody Government Pharmacy College,
    Rajkot – 360003, Gujarat (India)
    vivek7chavda@gmail.com

    Abstract
    This technology has just revolutionized the cancer treatment. It is clearly a tool of exceptional value in the functionalization of genes and their validation as potential targets for cancer chemotherapy. Furthermore, a rapidly expanding repertoire of antisense therapy based on the use of antisense oligonucleotides (AONs), small interfering RNAs (siRNAs), micro RNAs (miRNAs), ribozymes and other antisense compounds is being developed to block over expression of key oncogenes and other tumor promoting genes in the treatment of different tumors and many of these nucleic acid-based drugs have demonstrated impressive preclinical and clinical responses.This review highlight some of the cardinal feature of this technology.

  • BABY TOILETRIES : A SHORT EXPLANATION

    The constantly increasing sales volume of baby toiletries in the overall cosmetic market indicates their relative importance to the consumer, manufacturer, retailer and pediatrician. These products include:

  • MICROBALLOONS DELIVERY SYSTEM: AN INNOVATIVE ACCEPTABLE APPROACH IN GASTRORETENTIVE DRUG DELIVERY

    About Authors:
    Yashodhara Choubey*, Mr. Govind Bhandari, Mr. Avnish Sharma, Mr. Mukesh Mehra
    Mahakal Institute of Pharmaceutical Studies,
    Ujjain (M.P.), India
    *yashodhara.juhipharma@gmail.com

  • REVIEW ON GOLD NANOPARTICLES FOR CANCER TREATMENT

    About Authors:
    M. B. Shinde*, S.V.Usnale1, M. B. Sorde2, O.V. Kolgire3
    Department of quality assurance,
    Maharashtra College Of Pharmacy, Nilanga.
    Dist- latur (MS)
    *maheshinde7@gmail.com

  • STUDIES IN CONCURRENT PROCESS VALIDATION OF CEFIXIME DISPERSIBLE TABLET I.P.

    ABOUT AUTHORS:
    Mr. Diptesh A. Patel1*, Mrs. Pinkal H. Patel1, Mr. Rohit K. Patel2
    1Department of Quality Assurance, Baroda college of pharmacy, Vadodara, Gujarat, India.
    2Department of Quality Assurance, Kaptab Pharmaceutical, Vadodara, Gujarat, India.
    *dipteshpatel88@yahoo.com

  • PH-STIMULI SENSITIVE POLYMER AS A CARRIER FOR TARGETED DELIVERY SYSTEM: A REVIEW

    ABOUT AUTHORS:
    Girish Kumar Tripatha*, Satyawan Singha
    Bio-organic chemistry Laboratory,
    Saroj Institute of Technology & Management Lucknow, India
    *orgpharm@gmail.com

  • A REVIEW ON NEEDLE-FREE INJECTION SYSTEMS: NOVEL APPROACH TO DRUG DELIVERY

    About Authors:
    Waghmare P.V.*, Chinchole A.S.1, Chavan D.V.2, Dr.Bhusnure O.G.3
    Master of pharmacy, Department of Quality Assurance (*,1, 2,3)
    Maharashtra College of Pharmacy, Nilanga, Dist. Latur (MS) 413521, India
    *pradeep.waghmare90@gmail.com

  • A BRIEF REVIEW ON TREATMENT & PREVENTION OF CANCER

    ABOUT AUTHORS:
    Saurabh Kumar Singh*, Aruna Chandra Singh
    Department of pharmaceutical Chemistry, Rajiv Academy for pharmacy, Mathura,
    N.H. #2 Delhi-Mathura Bye-pass, P.O. Chhatikara,
    Mathura-281001.Uttar Pradesh, India
    *s_s_khirwar@yahoo.co.in

    ABSTRACT
    The rate of cancer rise is dramatic, doubling in the last 30 years. Furthermore, of the estimated 560,000 cancer victims who would die in 1997, most of them could have prevented their illness had they paid attention to some simple lifestyle factors.

    Although the number of cancer deaths continues to rise each year in the U.S., the per capita cancer mortality rate has just recently started to decline. This celebrated small decline was first announced by the National Cancer Institute in late 1996, but a careful retrospective review of the data indicated that the per capita cancer death rate peaked in 1991 and has ever so slowly declined thereafter. What was the reason for this decline? Not improved cancer treatments, but cancer prevention itself emerges as the cause for this good news. A national commitment to the prevention of cancer, largely replacing reliance on hopes for universal cures.

  • COMPARATIVE STATUS OF OXIDANT/ANTIOXIDANT IN PREGNANCY INDUCED HYPERTENSION AND CERVICAL DYSPLASIA

    About Author:
    *Seema Singh1, Sandeep Kumar Singh2
    1Department of Pharmacy, Northern India Engineering College, Lucknow (U.P.) India
    2Department of Pharmaceuticals Sciences, Dr. H S Guar University Sagar (M.P.), India
    *seema_b.pharm@rediffmail.com

    Abstract:
    Present study is aimed to delineate a co-relation between status of anti-oxidant enzymes, lipid peroxidation products with severity of Pregnancy Induced Hypertension (PIH) and cervical dysplasia. The study has been done on 66 patients out of whom 14 were normal pregnancy and had no disease, 31 patients of PIH and 21 patients having cervical dysplasia gr. I-II. Enzymatic activities of Superoxide dismutase (SOD), Catalase (CAT), vitamin C and vitamin E and malonaldehyde levels (MDA, a marker of lipid peroxides) were assessed spectrophotometrically. Mean Malonaldehyde level in PIH patients (8.48 ± 0.96) & Cervical patients (8.31 ± 1.25) in comparison to normal patients (4.88 ± 1.035), the rise was found highly significant (p < 0.001). The enzymatic activity of antioxidants such as Superoxide dismutase, Catalase, vitamin C and vitamin E was decreased in PIH patients & cervical dysplasia patients as compared to normal patients (p < 0.001). The difference was statistically significant (p < 0.001) whereas the same was observed in cervical dysplasia patients. No statistically difference was observed between the levels of antioxidants of PIH patients & cervical dysplasia patients (p < 0.01). Co-relation of Hb with MDA level showed that aneamic patients have raised level of MDA as compared to non aneamic patients. There is positive oxidant/antioxidant balance which may aggravate free radical damage during pre eclampsia and eclampsia with cervical dysplasia.

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