Articles

26 March 2014

A REVIEW ON OSMOTICALLY REGULATED SYSTEMS

25 March 2014

FLASH CHROMATOGRAPHY: AREA & APPLICATIONS

ABOUT AUTHORS:
Ayare P*, Khanvilkar V, Chalak N
Department of Quality Assurance,
Bharati Vidyapeeth’s College of Pharmacy, Navi Mumbai
abprachi@gmail.com

ABSTRACT
Most of the sophisticated analytical techniques like NMR, MS and FT-IR need sample in the extreme pure form which is usually achieved by Preparative column chromatography but it is time consuming. From past few decades, technique called as Flash chromatography is developed which is a modification of Preparative column chromatography. This is an air pressure driven technique comprising of medium and short column chromatography, optimised for rapid separation of organic compounds. Modern flash chromatographic system consists of pre-packed plastic cartridges wherein solvent is pumped through the cartridges to achieve separation. These systems are also linked with detectors and fraction collectors which can even be automated. It is a simple, fast and economic approach to preparative liquid chromatography for purification of chemical species.This review highlights the principle involved, instrumentation, general procedure and advancement in Flash chromatography along with its applications.

24 March 2014

ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF FIRST ORDER DERIVATIVE SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF PARACETAMOL AND PROPYPHENAZONE IN THEIR COMBINED PHARMACEUTICAL DOSAGE FORM

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23 March 2014

HISTORY OF CATIONIC VS ANIONIC: IN NASAL DRUG DELIVERY SYSTEM

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ABOOUT AUTHORS:
Manu Sharma¹, Shikha Chaudhary¹, Dharmendra Kumar^2*
¹ R.V.Northland institute, greater Noida, Dadri, UP, India²Brahmanand Group of Institution, 195, Khurja G.T Road, Buldshahar Uttar Pradesh, India.
*rvnimiet@gmail.com

ABSTRACT
Chitosan as cationic and pectin as anionic are natural polysaccharides which show great potential in nasal drug delivery system. Chitosan’s are strongly poly-cationic. They are derivatives of poly-N-acetyl-D-glucosamine. Chitosan’s have positive charge that is responsible for mucoadhesion and play an important role in nasal drug delivery system Pectin’s have several structural elements: Homogalactouronan are smooth and Rhamnogalactouronan are hairy which play a very important role.By methyl esterifications, pectin’s are divided in two types: High methoxypectin’s and low methoxypectin’s. Low methoxypectin’s are very important in the formulation of nasal gel, because they have properties to form the gel with calcium ion (Ca²⁺).

21 March 2014

PHYTOCHEMICAL SCREENING & EVALUATION OF ANTIMICROBIAL ACTIVITY OF GLYCYRRHIZA GLABRA LINN

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20 March 2014

MUSCULAR DYSTROPHY: A REVIEW

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19 March 2014

Q-ABSORBANCE RATIO SPECTROPHOTOMETRIC METHOD FOR THE SIMULTANEOUS ESTIMATION OF PARACETAMOL AND PROPYPHENAZONE IN THEIR COMBINED PHARMACEUTICAL DOSAGE FORM

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18 March 2014

ENDANGERED AQUATIC MEDICINAL PLANTS OF KERALA

ABOUT AUTHOR:
Uma Nath.U
Department Of Pharmaceutical Analysis,
Daleview College Of Pharmacy And Research Centre,
Punalal, Trivandrum, Kerala
umaanalysis@yahoo.co.in