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Shree Dhanvantary Pharmacy College

 

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  • Vacancy for Research Associate, Research Assistant at SDPARC - 3 posts

    Shree Dhanvantary Pharmaceutical Analysis and Research Centre (SDPARC) is a contract research organization established in 2006 and is managed by RIBOSOME PHARMA PVT. LTD., Surat. SDPARC offers a wide range of analytical & research services for small, medium and large scale pharmaceutical, ayurvedic, bulk drug, chemical, food and cosmetic industries.

    Post : Research Associate (Pharmacology)- 1 Post; and Research Assistant (Pharmacology)- 2 Posts

  • 4th International Conference on Theranostic Nanoparticles at Shree Dhanvantary Pharmacy College
  • Job as QA Executive, AR&D / QC Executive, Chemical and Store Section Executives in SDPARC - 4 posts

    Shree Dhanvantary Pharmaceutical Analysis and Research Centre (SDPARC) is a contract research organization established in 2006 and is managed by RIBOSOME PHARMA PVT. LTD., Surat. SDPARC offers a wide range of analytical & research services for small, medium and large scale pharmaceutical, ayurvedic, bulk drug, chemical, food and cosmetic industries. The centre is approved by the Food and Drug Control Administration (FDCA), Gujarat state as a public testing laboratory and is spread over 8,000 sq. ft. area.

  • REVIEW: COMBINED CANDESARTAN CILEXETIL AND PIOGLITAZONE HYDROCHLORIDE THERAPY IN METABOLIC SYNDROME
  • PHARMACOLOGY OF COMBINED MESALZINE AND RIFAXIMIN THERAPY TO INFLAMMATORY BOWEL DISEASE

    { DOWNLOAD AS PDF }

    ABOUT AUTHORS
    Prajapati Krishna V*, Raj Hasumati A, Jain Vinit C, Prajapati Neelam S.
    Department of Quality Assurance,
    Shree Dhanvantary Pharmacy College, Kim, Surat, Gujarat, India
    *krish1112k@gmail.com

    ABSTRACT
    This review article presents the pharmacology of combined Mesalazine and Rifaximin therapy especially in inflammatory bowel disease. Mesalazine is used as in anti-inflammatory agent, Non-Steroidal. Rifaximin is used in Gastrointestinal Agents, Anti-infective agent. The use of Rifaximin in combination with Mesalazine has been proved to provide beneficial effect in inflammatory bowel disease. The mechanism of Mesalazine and Rifaximin is quite different. Mesalamine and Rifaximin are two different types of drugs offering some symptomatic relief to the IBD patients. Mesalamine treats inflammation, whereas, Rifaximin reduces bio burden.
    Patent for combination of both drugs were approved by WIPO. The main objective of this review article is to provide pharmacological information of combined therapy of Mesalazine and Rifaximin to researcher in development of combined dosage form of this.

  • PHARMACOLOGY OF COMBINED RANOLAZINE AND AMIODARONE HYDROHLORIDE THERAPY TO TREAT ATRIAL FIBRILLATION
  • A REVIEW ON ANALYTICAL METHODS FOR RANOLAZINE DETERMINATION IN SYNTHETIC MIXTURE
  • DEVELOPMENT AND VALIDATION OF ANALYTICAL METHOD FOR SIMULTANEOUS ESTIMATION OF LAMOTRIGINE AND CLOZAPINE IN SYNTHETIC MIXTURE BY ABSORPTION CORRECTION METHOD

    { DOWNLOAD AS PDF }

    ABOUT AUTHORS:
    Priyanka P. Atodariya*, Hasumati A. Raj, Vineet C. Jain
    *Shree Dhanvantary Pharmacy Collage, Kim,
    Surat, Gujarat, India
    *atodariya.priyanka@yahoo.com

    ABSTRACT:
    The simple spectroscopic method has been developed for simultaneous estimation of Lamotrigine and Clozapine in synthetic mixture. Absorbance Correction Method involves the measurement of absorption at two wavelengths 307 nm (lmaxfor Lamotrigine) and 360 nm (lmax for Clozapine). The method was found linear between the range of 1-5 µg/ml for Lamotrigine and 6-30 µg/ml for Clozapine for method. The accuracy and precision was determined and validated statistically. Both the method showed good reproducibility and recovery with %RSD less than 1. The method was found to be rapid, specific, precise and accurate and can be successfully applied for the routine analysis for Lamotrigine and Clozapine in bulk and combined dosage form.

  • SIMULTANEOUS DETERMINATION OF ITOPRIDE HYDROCHLORIDE AND LANSOPRAZOLE IN SYNTHETIC MIXTURE USING SPECTROPHOTOMETRIC TECHNIQUE (FIRST ORDER DERIVATIVE METHOD

    { DOWNLOAD AS PDF }

    ABOUT AUTHORS:
    *Ashif I. Bhim1, Farhana V. Buchiy1, Hasumati A. Raj1, Vineet C. Jain2
    1Department of Qaulity Assurane, Shree Dhanvantary Pharmacy College, Kim, Surat, Gujarat, India.
    2Department of Pharmacognocy, Shree Dhanvantary Pharmacy College, Kim, Surat, Gujarat, India.
    bhimiqbal23@gmail.com

    ABSTRACT
    A simple, accurate and precise spectroscopic method was developed for simultaneous estimation of Itopride Hydrochloride and Lansoprazole in synthetic mixture using first order derivative zero-crossing method. Itopride Hydrochlorideshowed zero crossing point at 278.12nmwhile Lansoprazole showed zero crossing point at 244.58nm. The dA/dλ was measured at 244.12 nm for Itopride Hydrochloride and 278.12nmfor Lansoprazole and calibration curves were plotted as dA/dλ versus concentration, respectively. The method was found to be linear (r2>0.999) in the range of 5-25μg/ml for Itopride Hydrochloride at 244.58nm. The linear correlation was obtained (r2>0.996) in the range of 5-25 μg/ml for Lansoprazole at 278.12 nm. The limit of determination was 0.155μg/ml and 0.059μg/ml forItopride Hydrochloride and Lansoprazole, respectively. The limit of quantification was 0.472μg/ml and 0.179μg/ml for Itopride Hydrochloride and Lansoprazolerespectively. The accuracy of these method were evaluated by recovery studies and good recovery result were obtained greater than 99% shows first order derivation zero crossing. The method was successfully applied for simultaneous determination of Itopride Hydrochloride and Lansoprazolein binary mixture.

  • ABSORBANCE CORRECTION METHOD FOR SIMULTANEOUS ESTIMATION OF AMLODIPINE BESYLATE AND SIMVASTATIN IN SYNTHETIC MIXTURE

    { DOWNLOAD AS PDF }

    ABOUT AUTHROS:
    Vandana M Patel*, Hasumati A Raj, Vineet C Jain
    *Shree Dhanvantary College of Pharmacy,
    Kim, Surat, Gujarat, India.
    vandanapatel@gmail.com

    ABSTRACT
    A simple, accurate and precise spectroscopic method was developed for simultaneous estimation of Amlodipine besylate and Simvastatin in synthetic mixture using Absorbance correction  method. At  360.80  nm (λmax of Amlodipine besylate) Simvastatin has zero absorbance so Amlodipine besylate is directly estimate at 360.80 nm. At 237.60 nm (λmax of Simvastatin) both drugs have some absorbance so Simvastatin is estimate at 237.60 nm using absorbance correction method. The method was found to be linear (r2>0.999) in the range of 5-10 μg/ml for Amlodipine besylate at 360.80 nm. The linear correlation was obtained (r2>0.999) in the range of 5-10 μg/ml for Simvastatin at 237.60 nm. The limit of determination was 0.17 μg/ml and 0.10μg/ml for Amlodipine besylate and Simvastatin, respectively. The limit of quantification was 0. 54μg/ml and 0. 32μg/ml for Amlodipine besylate  and Simvastatin, respectively. The accuracy of these method were evaluated by recovery studies and good recovery result were obtained greater than 99%. The method was successfully applied for simultaneous determination of Amlodipine besylate and Simvastatin in binary mixture.

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