Skip to main content

B.K. Mody Government Pharmacy College

  • BIOTECHNOLOGICAL/BIOLOGICAL PRODUCTS: ABOUT ITS STABILITY TESTING

    { DOWNLOAD AS PDF }

    ABOUT AUTHORS
    Vivek P. Chavda1*, Dharmesh Shaliya2, Bhargav Patel3, Ashish Gabani4
    1Department of Pharmaceutics, B.K. Mody Government Pharmacy College, Rajkot, Gujarat, India
    2Quality Assurance, Intas Pharmaceuticals Ltd., Ahmedabad, Gujarat, India
    3Quality Assurance, Zydus cadila pharmaceuticals Ltd., Ahmedabad, Gujarat, India
    4 Intas Biopharmaceuticals Ltd., Ahmedabad, Gujarat, India

    * vivek7chavda@gmail.com

    ABSTRACT
    The drug delivery systems have made some of the technological advances especially in the case of biopharmaceuticals. When one talks about biotechnological product stability of drug product becomes main culprit due to dynamic nature of drug molecule. This review is grafted using ICH and other regulatory guidelines to provide an overview to stability testing of such molecules.

  • MONOCLONAL ANTI BODIES FOR CANCER TREATMENT

    ABOUT AUTHOR:
    Vivek P. Chavda
    Department of Pharmaceutics, B.K. Mody Government Pharmacy College,
    Rajkot – 360003, Gujarat (India)
    vivek7chavda@gmail.com

    ABSTRACT
    Cancer is one of most cogent culprit for causes of mortality in society. Chemotherapy, radiation therapy and surgery are the elements which are endorsed to combat it. Nowadays antibodies are also gaining much attention in cancer treatment. Antibodies are found to be important and most promising and target specific therapeutic agents for cancer due to their epitope specific interaction. Many clinically useful antibodies can manipulate tumour-related signaling. In addition, antibodies exhibit various immunomodulatory properties and, by directly activating or inhibiting molecules of the immune system, antibodies can promote the induction of antitumour immune responses. Antibody-drug conjugates prove to be more promising in the treatment.

  • ANTISENSE TECHNOLOGY: MAKING GOOD SENSE FOR CANCER TREATMENT

    About Author:
    Vivek P. Chavda
    Department of Pharmaceutics, B.K. Mody Government Pharmacy College,
    Rajkot – 360003, Gujarat (India)
    vivek7chavda@gmail.com

    Abstract
    This technology has just revolutionized the cancer treatment. It is clearly a tool of exceptional value in the functionalization of genes and their validation as potential targets for cancer chemotherapy. Furthermore, a rapidly expanding repertoire of antisense therapy based on the use of antisense oligonucleotides (AONs), small interfering RNAs (siRNAs), micro RNAs (miRNAs), ribozymes and other antisense compounds is being developed to block over expression of key oncogenes and other tumor promoting genes in the treatment of different tumors and many of these nucleic acid-based drugs have demonstrated impressive preclinical and clinical responses.This review highlight some of the cardinal feature of this technology.

Subscribe to B.K. Mody Government Pharmacy College