Madhya Pradesh

FORMULATION AND CHARACTERIZATION OF MELOXICAM LOADED MICROEMULSION FOR THE TREATMENT OF RHEUMATOID ARTHRITIS

ABOUT AUTHOR:
Verma Siddharth
Sri Ram Institute of Technology,
ITI Jabalpur M.P. 482003
luckyverma84@gmail.com

ABSTRACT
Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disorder that may affect many tissues and organs, but principally attacks synovial joints. The process produces an inflammatory response of the synovium (synovitis) secondary to hyperplasia of synovial cells, excess synovial fluid and the development of pannus in the synovium. Various treatments are available. Non-pharmacological treatment includes physical therapy, orthoses, occupational therapy and nutritional therapy. Analgesia (painkillers) and anti-inflammatory drugs including steroids are used to suppress the symptoms, while disease-modifying antirheumatic drugs (DMARDs) are often required to inhibit or halt the underlying immune process and prevent long-term damage. In recent times, the newer group of biologics has increased treatment options.

A REVIEW ON PARASITIC WORMS AND ANTHELMENTIC DRUG

About author:
Priya Diwedi
M.Pharm
Bhopal institute of technology and science-pharmacy, Bhopal (M.P)
Priya.diwedi07@gmail.com

ABSTRACT:
Anthelmintics or antihelminthics are drugs that expel helminth parasitic worms (helminths) from the body, either by stunning or killing them. They may also be called vermifuges (stunning) or vermicides (killing). They belong to two major groups of animals, the flatworms or Platyhelminthes (flukes and tapeworms) and the roundworms or Nematoda. Albendazole, mebendazole and praziquantel are the commonly used drugs acting as anthelmintics having broad spectrum activity and high cure rates due to the sustainability of the periodic emergence of resistance. This article reviews the worm infection, their lifecycle and its outcome, symptoms of worm infection and its prevention,marketed formulation for anthelmentic activity and their limitation and herbal drug used for anthelmentic activity.

HERBAL TREATMENT AND RHEUMATOID ARTHRITIS: AN OVERVIEW

About Authors:
Prabhakar Sharma*1, Prakash Pandey1, Sunil Roshan1, Ashish Garg2, Vikas Pandey3, Anil Pasi4
1Department of Pharmacognosy, GRKIST (Pharmacy), Jabalpur, M.P.
2Department of Pharmaceutics, GRKIST (Pharmacy), Jabalpur, M.P.
3Department of chemistry, RDVV, Jabalpur, M.P.
4College of pharmacy, IPS academy, Indore, M.P.
*mr.pks19@gmail.com, pksmp11@gmail.com

Abstract
Sometimes Herbal medicines are referred as herbalism or natural medicine is the use of herbs for their therapeutic or medicinal value, an herb is a plant or plant part valued for its medicinal, aromatic or savory qualities. Herb plants produce and contain a variety of chemical substances that act upon the body herbalism has a long tradition of use outside of conventional medicine. It is becoming more main stream as improvements in analysis and quality control along with advances in clinical research show the value of herbal medicine in the treating and preventing disease. By definition, ‘traditional’ use of herbal medicines implies substantial historical use, and this is certainly true for many products that are available as ‘traditional herbal medicines’.

NUTRACEUTICALS

ABOUT AUTHORS:
Miss Apoorva Bhatnagar1, Dr. S. C. Mahajan2
1Mahakal institute of pharmaceutical studies,  
2Director at Mahakal Institute of Pharmaceutical Studies,
Ujjain (m.p.)  456010
*apy1590bhtngr@gmail.com

ABSTRACT:
Foods and food habits in today’s lifestyle have lead to the disturbances in an ideally nutritionally balanced body. Therefore in such state if “food be your medicine” then it would be great to achieve a healthy body and mind. The article covers major food products and nutraceuticals and their role they play in human health.

IMPURITY PROFILE: - STUDY A BETTER WAY FOR QUALITY CONTROL OF PHARMACEUTICALS PRODUCTS

ABOUT AUTHORS:
*Ramchandra Gupta2, Prabhakar Sharma2, Prakash Pandey2, Pratik Jain1, Ajay Shukla3
1Department of Pharmacognosy,
2Department of Pharmaceutics,
3Department of Pharmaceutical Chemistry

1,2,3Guru Ramdas Khalsa Institute of Science and Technology (Pharmacy) Jabalpur, 483001, M.P.
*ramchandra.gupta667@gmail.com

ABSTRACT
In the pharmaceutical world, an impurity is considered as any other organic material, besides the drug substance, or ingredients, arise out of synthesis or unwanted chemicals that remains with API’s. Pharmaceuticals impurities are the unwanted chemicals that remain or are generated during the formulation of medicines. The presence and quantity of impurities in pharmaceutical drugs can have a significant impact on their quality and safety, with the continuous pressure for increased industry productivity, there is urgent need for a systematic and comprehensive drug impurity profiling strategy. The impurities present in the drug are adversely affecting the quality of the drug product. There are various types of impurities like starting materials, intermediates, penultimate impurity, by product and degradation product. Impurity profiling helps in detection, identification and quantification of various types of impurities as well as residual solvents in bulk drugs and in pharmaceutical formulations. It is a best way to characterize quality and stability of bulk drugs and pharmaceutical formulations. This review paper deals with the impurity profile of pharmaceuticals.

Work as Lab Technician in Modern Institute of Pharmaceutical Sciences

Modern Institute of Pharmaceutical Sciences (MIPS), Indore was established in 2007. With intent to establish an institution of repute for creating technical experts and to translate their potential to meet the requirements of Pharmaceutical Industries and meet the global challenges faced by them. MIPS shall endeavor to impart theoretical lectures coupled with practical training and understanding of pharmaceutical industry.

BUTEA MONOSPERMA A TRADITIONAL MEDICINAL PLANT: - AN OVERVIEW

About Authors:
Sunil Roshan1, Prabhakar Sharma*1, Ramchandra Gupta1, Sudhakar Sharma2
1Department of Pharmacognosy, GRKIST (Pharmacy)
2Takshashila Institute Of Science And Technology
Jabalpur, M.P.
*prabhakar.sharma071026@gmail.com

Abstract
The traditional systems of medicine together with homoeopathy and folklore medicine continue to play a significant role largely in the health care system of the population. Butea monosperma(palas) belonging to the family leguminosae grown wildly in many parts of India. The plant is highly uses by the rural and tribal people in curing various disorders. Flowers are used as drug in many ailments like eye disease, chronic fever, enlargement of spleen, leucorrhoea, epilepsy, leprosy, antifungal activity, anti-inflammatory activity, liver disorders antifertility activity and gout etc. The plant parts are used in the form of extract, juice, infusion, powder and gum. The present paper enumerates various pharmacognostic and pharmacological aspects of the plant. This review also summaries the therapeutic potential of this plant.This is a moderate sized deciduous tree which is widely distributed throughout India, Burma and Ceylon, popularly known as 'dhak' or 'palas', commonly known as ‘flame of forest’. In this review an attempt has been done to highlight the work on Butea monosperma having pharmacological potential.

AN OVERVIEW: ON SUPERDISINTEGRANTS

ABOUT AUTHORS:
Rahul Tiwari*1, R.C. Jat1, Narendra Sharma1, Arvind Singh Rathore1
1Shri Ram College Of Pharmacy,
1Banmore, Morena, India -476444
*rt30022@gmail.com, arvindsingh.rathore21@gmail.com

ABSTRACT
Disintegrants are substances or mixture of substances added to the drug formulation that facilitates the breakup or disintegration of tablet or capsule content into smaller particles that dissolve more rapidly than in the absence of disintegrants. In dosage forms, solid orals gain maximum popularities, about 85%, because of many advantages over others. The therapeutic activity of these formulations is obtained through a typical manner like disintegration followed by dissolution. Hence disintegration has major role for facilitating drug activity and thus gain popularity among other dosage forms. Superdisintegrants are generally used at a low level in the solid dosage form, typically 1-  10 % by weight relative to the total weight of the dosage unit. The present study comprises the various kinds of superdisintegrants which are being used in the formulation to provide the safer, effective drug delivery with patient's compliance. In this review article, more emphasis is given on application and usage of various superdisintegrants comparing with other disintegrants in reference to available scientific studies. The various sources of superdisintegrants and their modification to improve disintegration property are also high-lighted.


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