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  • COMPARATIVE STATUS OF OXIDANT/ANTIOXIDANT IN PREGNANCY INDUCED HYPERTENSION AND CERVICAL DYSPLASIA

    About Author:
    *Seema Singh1, Sandeep Kumar Singh2
    1Department of Pharmacy, Northern India Engineering College, Lucknow (U.P.) India
    2Department of Pharmaceuticals Sciences, Dr. H S Guar University Sagar (M.P.), India
    *seema_b.pharm@rediffmail.com

    Abstract:
    Present study is aimed to delineate a co-relation between status of anti-oxidant enzymes, lipid peroxidation products with severity of Pregnancy Induced Hypertension (PIH) and cervical dysplasia. The study has been done on 66 patients out of whom 14 were normal pregnancy and had no disease, 31 patients of PIH and 21 patients having cervical dysplasia gr. I-II. Enzymatic activities of Superoxide dismutase (SOD), Catalase (CAT), vitamin C and vitamin E and malonaldehyde levels (MDA, a marker of lipid peroxides) were assessed spectrophotometrically. Mean Malonaldehyde level in PIH patients (8.48 ± 0.96) & Cervical patients (8.31 ± 1.25) in comparison to normal patients (4.88 ± 1.035), the rise was found highly significant (p < 0.001). The enzymatic activity of antioxidants such as Superoxide dismutase, Catalase, vitamin C and vitamin E was decreased in PIH patients & cervical dysplasia patients as compared to normal patients (p < 0.001). The difference was statistically significant (p < 0.001) whereas the same was observed in cervical dysplasia patients. No statistically difference was observed between the levels of antioxidants of PIH patients & cervical dysplasia patients (p < 0.01). Co-relation of Hb with MDA level showed that aneamic patients have raised level of MDA as compared to non aneamic patients. There is positive oxidant/antioxidant balance which may aggravate free radical damage during pre eclampsia and eclampsia with cervical dysplasia.

  • Career opportunity for M.Pharm, M.Sc in CSIR-Central Drug Research Institute | 15 Posts

    CSIR-Central Drug Research Institute, Lucknow is a premier R&D Institute under the aegis of the Council of Scientific and Industrial Research (CSIR), New Delhi which is an autonomous body under Department of Scientific and Industrial Research, Government of India.

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  • Application are invited only from the retired employees for Pharmacist - 2 posts

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  • HERBAL REMEDIES USED IN THE TREATMENT OF EPILEPSY

    ABOUT AUTHORS:
    Sachchidanand Pathak*, L Singh, T Singh, S K Sharma
    Sunder Deep Pharmacy College,
    Ghaziabad, Uttar Pradesh, India
    sachchidanand.pathak904@gmail.com

    ABSTRACT
    This article has been made to review of following plants used for the antiepileptic activity. The plant sources of India are likely to provide effective antiepileptic agents. Herbs have a vital role in the prevention and treatment of convulsion. The phytochemical exploration of these herbs has contributed to some extent in this race for the discovery of new antiepileptic drugs (AED). In recent years owing to the fear of side effects people prefer more and more use of natural plant products for convulsions. This review also helps to summarize the diverse methodologies and ways to evaluate the potential natural compounds having antiepileptic activity.

    Convulsion is the second most common neurologic disorder after stroke. Approximately 1% of the world’s population has convulsion, it is a condition where the patient suffers from recurrent seizures. Control to seizures numerous conventional drugs came into existence. Most of the epileptic patients need polytherapy of conventional anticonvulsants and still not 100% cured.

    The major drawback due to these agents is their chronic side effects and drug interactions which restrict its use. On the other hand nature has provided us plants to be used as natural remedy for diseases with least side effects and insignificant drug interactions. This has motivated the researchers towards herbal remedy for anticonvulsant activity. In this review, herbal drugs have been discussed with more emphasis on the research advancements of traditional or herbal anticonvulsants.

  • Admission opportunity in B.Pharm and M.Pharm at Lovely Professional University

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  • Shoolini University offers admission for B.Pharmacy, M. Pharmacy (Pharmaceutics, Pharm. Chemistry, Pharmacology, Pharmacognosy, Quality assurance, Biotechnology), B. Pharm MBA (Integrated), and PhD programs

    Shoolini University is is located in a thick grove of pine trees, 14 km from Solan with cool summers and pleasant winters, and an ideal destination for academic and research romance. It has adopted research driven model and its strength emanates from Sound Governance and Cultural Heritage. Governing Body is comprised of distinguished academicians, entrepreneurs, professional executives and consultants.

  • Walk in interview for the post of Senior Research Fellow, Senior Research Assistant, Project Assistant Level-I,II & III

    The Indian Institute of Toxicology Research (IITR), Lucknow, a premier institute under the Council of Scientific and Industrial Research (CSIR) is involved in multidisciplinary R&D programmes of both basic and applied nature across scientific disciplines for economic, environmental and societal benefits for the people of India.

  • Require Faculties in Mangalayatan University Aligarh

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