Uttar Pradesh

The Central Council for Research in Homoeopathy invites Consultant (Botany), Consultant (Chemistry), Data Entry Operator

The Central Council for Research in Homoeopathy (CCRH), an autonomous body under the Department of AYUSH, Ministry of Health and Family Welfare, Government of India intends to engage the following categories of personnel on contract basis for a period of 06 (six) months for Homoeopathic Pharmacopoeia Laboratory (HPL), Ghaziabad (Uttar Pradesh).

NASAL DRUG DELIVERY SYSTEM: A COMPLETE REVIEW

About Authors:
Dharmendra Kumar*1, Sumedha Bansal1
1Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology,
Meerut, Uttar Pardesh, India, 250005
*rvnimiet@gmail.com

Abstract:
In present era, nasal drug delivery system has been considered as potential and favourable route of drug delivery because it provides patient compliance, easy to administration, bypass first pass metabolism, excellent penetration, low dose required, rapid absorption and gives desirable effects. So many times nasal drug delivery has been considered as alternative of parenteral route. The purpose of this review, to provide a complete information about nasal drug delivery system such as advantage, limitations, anatomy of nose, mechanism of drug absorption, factors affecting of nasal drug delivery, absorption improvement aspects, novel drug formulations, types of nasal drug delivery system with uses of nasal drug delivery in various disease. So we have expectation, that researches and others cited person get benefitted from this review.

SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME NOVEL 3-(2-(1H-INDOL-2-YL) PHENYL)-2-ARYLIMIDAZO[4,5-b]INDOLES

About Authors:
Aditya Dixit1, Gyanendra Kumar Sharma2, Devender Pathak*3
1M. Pharmacy (Pharmaceutical Chemistry)
2Associate Professor (Pharmaceutical chemistry)
3Director, Professor and Head of the Dept. (Pharmaceutical Chemistry)
Rajiv Academy for Pharmacy, Mathura,
Delhi-Mathura Highway, Chhattikara, 281006, India
dev_15@rediffmail.com*, adixit70@gmail.com

ABSTRACT
A traditional but effective method of developing new targets is lead molecule modification, where an existing popular drug from the market is taken as a lead and similar derivatives are synthesized. With the advent of modern techniques conventional methods have lost their gleam but, reactions are still best understood when performed by the conventional techniques. One such endeavor has been made here where indole has been used as a parent moiety and by adding some functional groups some novel indole derivatives were synthesized and screened for their in vitro antitubercular, and anticancer activity. This synthesis of some fresh indole derivatives was done by using various benzaldehyde derivatives and 2-(o-Aminophenyl)indole in acidic condition then with ammonium acetate and isatin in presence of glacial acetic acid.. The structures of newly synthesized compounds were characterized by IR, 1H NMR, MASS and elemental analysis.Compounds 3h & 3i showed good antitubercular activity and 3d, 3e & 3g showed good anticancer compared to the standard drug.


DENDRIMERS FOR NOVEL DRUG DELIVERY: AN OVERVIEW

About Authors:
Roopesh Sachan
*1, Prof. Satyanand Tyagi2, Tarun Parashar1, Soniya1, Patel Chirag J*3,Patel Pinkesh3, Rishikesh Gupta4
1
*Department of Pharmaceutics, Himalayan Institute of Pharmacy and Research, Rajawala, Dehradun, Uttarakhand, India-248007.
2
President & Founder, Tyagi Pharmacy Association (TPA) & Scientific Writer (Pharmacy), Chattarpur, New Delhi, India-110074.
3
Department of Pharmaceutics, Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, Rajasthan, India-302020.
4
Institute of Pharmacy, Bundelkhand University, Jhansi, Uttar Pradesh, India-284128.
*roopeshsachan@gmail.com, +91-9557469989, 9236167104

ABSTRACT:
Nanoparticle drug-delivery systems are the popular ones as are able to increase the selectivity and stability of therapeutic agents. However reticuloendothelial system (RES) uptake, drug leakage, immunogenicity, hemolytic toxicity, cytotoxicity, hydrophobicity restrict the use of these nanostructures. These shortcomings are overcome by surface engineering the dendrimer such as Polyester dendrimer, Citric acid dendrimer, Arginine dendrimer, Glycodendrimers, PEGylated dendrimers, etc.The field of Dendrimers has recently emerged as the most commercially viable technology of this century because of its wide-ranging potential applications in many fields such as: healthcare, electronics, photonics, biotechnology, engineering products, pharmaceuticals, drug delivery, catalysis, electronic devices, environmental issues and nanotechnologies. Dendrimer as a drug delivery agent is a promising, safe and selective drug delivery option.

Application are invited form Lecturer ( Pharmacy) in Public Service Commission, Uttar Pradesh | Government Job

Applications will be accepted only when fee is deposited in the Bank upto prescribed last date for fee submission. If the fee is deposited in bank after prescribed last date for fee submission, the candidature of the candidatewill be rejected and application will not be accepted. Once fee deposited in the bank will not be refunded to the candidate in any condition.

HEALTH BENEFITS OF WHITE TEA: A CLINICAL REVIEW

About Authors:
Prof. Satyanand Tyagi*1, Patel Chirag J2, Pinkesh Patel2,
Chaudhari Bharat2, Tarun Parashar3, Soniya3, Ankur Massey4
*1President & Founder, Tyagi Pharmacy Association (TPA) & Scientific Writer (Pharmacy), Chattarpur, New Delhi, India-110074.
2
Department of Pharmaceutics, Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, Rajasthan, India-302020.
3
Department of Pharmaceutics, Himalayan Institute of Pharmacy and Research, Rajawala, Dehradun, Uttarakhand, India-248007.
4
Institute of Pharmacy, Bundelkhand University, Jhansi, Uttar Pradesh, India-284128.
*sntyagi9@yahoo.com
,+91-9871111375/9582025220

ABSTRACT:
Tea has been used as medicine for centuries. Now modern science is discovering what people in China and throughout the world have long known: tea is good for us. While green and black teas are very healthy, white tea is the least processed tea and has the highest antioxidant levels.
It may be the supreme Drink of Health.By now we can see that white tea has a great range of effects on the body and a tremendous number of benefits to our health. Its supreme power is in preventing disease and disorder. White tea protects against cancer, heart disease, and stroke, the leading causes of death in the industrial world, as well as numerous other conditions. It eases the symptoms of illness and promotes recovery. White tea strengthens the circulatory and immune systems as well as bones and teeth, and builds healthy skin. It is a superb tonic and one of Nature's great gifts. White tea has many other benefits to offer. It may reduce blood sugar and help prevent and alleviate the symptoms of diabetes. It reduces stress and increases energy. White tea may or may not aid in weight-loss. Studies suggest tea may increase metabolism and encourage the body to burn more fat, but a balanced diet and regular exercise are more likely to produce results. Still, adding white tea to our weight-loss plan can't hurt. Generally two cups of white tea is recommended per day for heart health and gastro-intestinal health and to get other health benefits. The aim of present article is to enumerate various health benefits of white tea especially its role in prevention of cardio-vascular diseases. An attempt is also made to focus or highlights on history, contents, manufacturing, production, varieties as well as recent studies as related to clinical uses of white tea.

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