Rajasthan

About Authors:
Arshad Hala^*1, Prof. Rajesh Dholpuria¹, Nilesh sovasia^1
1 Seth G. L. Bihani S. D. College Of Technical Education,
Institute Of Pharmaceutical Sciences & Drug Research,
Gaganpath, Sri Ganganagar, Rajasthan 335001
*Arshad_hala@yahoo.com

ABSTRACT:
A patent is one of the forms of intellectual property. The object of patent law is to encourage scientific research, new technology and industrial progress. The grant of exclusive privilege to own, use or sell the method or product patented for a limited period, stimulates new inventions of commercial utility. The price of the grant of the monopoly is the disclosure of the invention at the patent office, which after the expiry of the period of monopoly, passes into public domain. An invention which must be new and useful. It must have novelty and utility. The patents are granted to encourage inventions and to secure that the inventions are worked in India on a commercial scale and to the fullest extent that is reasonable practicable without undue delay. So true inventor required to know how to get patent in india and other countries through his self or legal representative. Without patent no one use, sell, and research on invention.This review looks into procedure to obtain patent in india.

G.B. Pant Institute of Himalayan Environment and Development (GBPIHED) was established in 1988-89, during the birth centenary year of Bharat Ratna Pt. Govind Ballabh Pant, as an autonomous Institute of the Ministry of Environment and Forests (MoEF), Govt.

About Authors:
¹Sahu Deepak*, ²Ketawat Santosh
¹Ass.Professor, Geetanjali Institute of Pharmacy,
²Lecturer, Geetanjali Institute of Pharmacy,
Dabok, Udaipur [Rajasthan] – 313022
*deepak.sahu.bhl@gmail.com

Abstract
Tablet is the most preferred oral dosage form, due to many advantages it offers to formulators as well as physicians and patients. However, the process of manufacturing tablets is complex. Hence, careful consideration has to be given to select right process, and right excipients to ultimately give a robust, high productivity and regulatory compliant product of good quality.

About Authors:
Patel Chirag J*, Asija Rajesh, Asija Sangeeta
Maharishi Arvind Institute of Pharmacy, Department of Pharmaceutics,
Jaipur, Rajasthan.
*chirag.bangalore@gmail.com

ABSTRACT
Solubility, the phenomenon of dissolution of solute in solvent to give a homogenous system, is one of the important parameters to achieve desired concentration of drug in systemic circulation for desired pharmacological response. Low aqueous solubility is the major problem encountered with formulation development of new chemical entities as well as for the generic development. The insufficient dissolution rate of the drug is the limiting factor in the oral bioavailability of poorly water soluble compounds. This review discusses BCS classification, carriers for solubility enhancement and different techniques for solubility enhancement.Various techniques are used for the enhancement of the solubility of poorly soluble drugs which include micronization, nanonization, sonocrystallization, supercritical fluid method, spray freezing into liquid and lyophilization, evaporative precipitation into aqueous solution, use of surfactant, use of co-solvent, hydrotropy method, use of salt forms, solvent deposition, solubilizing agents, modification of the crystal habit, co-crystallisation, complexation and drug dispersion in carriers.Selection of solubility improving method depends on drug property, site of absorption, and required dosage form characteristics.With the advent of combinatorial chemistry and a high throughput screening, the number of poorly water soluble compounds has increased solubility. A success of formulation depends on how efficiently it makes the drug available at the site of action.The purpose of this review article is to describe the techniques of solubilization for the attainment of effective absorption with improved bioavailability.

About Authors:
Kapil Sharma^*1, Subhash Gupta², Priyanka Sharma^1
1Yaresun Pharmaceutical Pvt. Ltd.,India.
²Oasis test house ltd.
jaipur-302006,rajasthan,india.
*pharma_kapil@rediffmail.com

ABSTRACT
This paper describe a simple, precise and economical spectrophotometric method for the quantitative determination of Deflazacort(DFCT) in tablet dosage form. Method is based on the estimation of DFCT in aqueous acetonitrileat 246 nm. Beer’s law was obeyed in the concentration range of 4-14 µg/ml. The accuracy of the method was assessed by recovery studies and was found to be 99.38±0.15 for DFCT. Results of the analysis were validated statistically so that it can be used for routine analysis of DFCT in tablet dosage form.