Amravati

About Authors:
Mohd Farhan
Department of Pharmacology,
Vidyabharti college of pharmacy
Amravati.
farhan.pharma66@gmail.com

Abstract:
The herbal medicine are in the great demand in the developed as well as developing countries for primary health care because of their large biological activities, higher safety margin and lesser cost. one of the common traditional herbal drug is Emblica officinalis, commonly known as Amla, is a member of a small genus Emblica (Euphorbiaceae). It grows in tropical and subtropical parts of China, India, Indonesia and the Malay Peninsula. All parts of the plant are used for medicinal purpose. The fresh (or) the dry fruit is used in traditional medicines for the treatment of diarrhoea, jaundice and inflammations. The pulp of the fruit is smeared on the head to dispel headache and dizziness Emblica officinalis leaves and fruit have been used for fever and inflammatory treatments by rural populations in its growing areas. The earlier study have demonstrated potent anti-microbial, adaptogenic, hepatoprotective, anti-tumour and anti-ulcerogenic activities in the fruits of Emblica officinalis. Leaf extracts have been shown to posses anti- inflammatory activity. vitamin C, tannins and flavanoids present in amla have very powerfull antioxidant activity. Due to rich in vitamin C amla is successfully use in the treatment of human scurvy.

About Authors:
H.S.Sawwalakhe*, J.M.Maidankar, M.A.Channawar, Dr.A.V. Chandewar
P. W. College of Pharmacy, Yavatmal,
Amravati university
*hemant_11sep@rediffmail.com

ABSTRACT:
The demand for mouth dissolving tablets has been growing during the last decade especially for elderly and children who have swallowing difficulties. Chlorpheniramine maleate is a non-steroidal anti-inflammatory drug (NSAID) histamine H1 antagonist with antihistamine drug it is commonly used  in allergic reactions, hay fever, rhinitis, urticaria, and asthma. The main criteria for mouth dissolving tablets are to disintegrate or dissolve rapidly in oral cavity with saliva in 15sec to 60sec with need of water. The disintegrants used should fulfill the criteria by disintegrating the tablets in specified time limit.in the present investigation variety of super disintegrants Crospovidone, sodium starch glycolate,kyron t-314 , were selected and tablets were prepared by direct compression method in different concentration like 3%,6% and 8%. The prepared tablets were evaluated for weight variation, hardness, friability, in vitro disintegration time, wetting time, in vitro dissolution study, etc.formulation f-9 shows the lowest disintegration time (29sec) and wetting time (37sec). In vitro dissolutionstudies revealed that formulation F-9 containning 9% t-314  showed 98% drug release at the end of 10 min.

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About Author:
Amol.A.Dambal,
Department of Pharmacognosy and Phytochemistry
Govt. College of pharmacy, Kathora naka,
Amravati-444604. (M.S.), INDIA.

ABSTRACT:
The herbal remedies have been employed in various medical systems for the treatment and management of different diseases. The plant Terminalia arjuna has been used in different system of traditional medication for the treatment of diseases and ailments of human beings. The plants contain Arjunilic acid, Triterpine glycosides like Arjunetosides I, II, III, IV, Arjunine and Arjunetein. The bark is rich in Saponnins, natural anti-oxidants (flavonoids-arjunone,arjunolone,leteilin), gallic acid, ellagic acid , phytosterols, rich in minerals like ca,  mg, zn and co, reducing sugars & coloring matter. It has been reported as Cardio tonic, Hepato-protective, Immunomodulatory, Antihyperglycemic, Antihyperlipidemic, Analgesic and Anti-Inflammatory, Antibacterial and Antiulcer properties.The current study is therefore carried out to provide requisite phytochemical and Pharmacological detail about the plant. The plant is cultivated in different parts of India on a small scale at present However; systematic information on different aspects of this species is not available. In this review, an attempt has been made to present this information.

About Authors:
Sudhir Ghawade,
Vidyabharati college of pharmacy,
Amravati

Abstract:
In recent times, focus on plant research has increased all over the world.Caesalpinia crista (Caesalpiniaceae)plant is well known for its medicinal and therapeutic values in Indian Ayurveda.The Indian traditional scriptures as well as the Ayurvedic texts have various references to the use of this plant. The bitter principles Bonducin and Natin are the primary constituent of Caesalpinia crista apart from linolic acid, fatty acid, setasitosterol and different diterpenes  which mainly believed to be responsible for its wide therapeutic action. The plant has been recommended for the treatment of various diseases and disorders such as Antispasmodic, Malarial fever, leucorrhea, abdominal pain , rheumatoid, arthritis, diabetes,cystic fibrosis,  amenorrhoea. The herb is used both, internally as well as externally. The present review attempts to provide comphrensive information on pharmacology, phytochemical study,toxicity, traditional uses and current research prospects of the herb.

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About Author:
Vijay M. Waghulkar^1* (M.Pharm, D.B.M.), Dr. Supriya S. Deshpande² (M.Pharm, Ph.D), Pooja A. Kohle³  (M.Sc)
*Corresponding author
1. Lecturer, Dept of Quality Assurance
Vidyabharati, College of Pharmacy, Camp, Amravati – 444601,
Maharastra, India.

2.Professor and HOD
Punjabrao Memorial Medical College of Pharmacy,
Panchvati,  , Amravati – 444602,
Maharastra, India

3. Lecturer,Dept. Cosmectic Technology
Vidyabharati Mahavidyala, Camp, Amravati – 444601,
Maharastra, India.

Abstract
Diabetes mellitus is caused due to deficiency in production of insulin by the pancreas, or by the ineffectiveness of the insulin producD.Diabetes mellitus often referred to as diabetes—is a condition in which the body either does not produce enough, or does not properly respond to, insulin, a hormoneproduced in the pancreas. Insulin enables cells to absorb glucose in order to turn it into energy. This causes glucose to accumulate in the blood, leading to various potential complications.

To overcome such complication Indian scientist have develop new techniques for diabetics i.e. single shot insulin which ,  is very essentials, blessful, create new ray of hope to the patients of diabetics ,give relief upto 120 days.

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