sangli

ABOUT AUTHORS
Salman S. Dhankwala*, Ajinkya N. Gavsane, Prithvirj M. Ghuli, Sagar A. Jadhav
Department of Pharmaceutical Chemistry,
Appasaheb Birnale College of Pharmacy,
Sangli, Maharashtra, India
*salman.2.dhankwala@gmail.com
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ABSTRACT
Ischemic heart diseases are a major public health problem, it includes disorders of the heart and blood vessel. Ischemia is a condition in which the blood flow (and thus oxygen) is restricted or reduced in a part of the body.Cardiac ischemia is the name for decreased blood flow and oxygen to the heart muscle It's the term given to heart problems caused by narrowed heart arteries. When arteries are narrowed, less blood and oxygen reaches the heart muscle. This is also called coronary artery disease and coronary heart disease. This can ultimately lead to attack. Ischemia often causes chest pain or discomfort known as angina pectoris. Disease is diagnosed according to medical parameters; following diagnosis of the disease the treatment is started. The treatment is includes in medicines of Heart diseases and is as well as lifestyle.

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ABOUT AUTHORS
J. Y MANURE *, N. S NAIKWADE, P. J SHIROTE, S.A BAGWAN AND K. M KULKARNI
Department of Pharmaceutical Chemistry,
Appasaheb Birnale College of Pharmacy,
South Shivaji Nagar, Sangli- 416416, Maharashtra, India.
^*javeedmanure.98600@yahoo.com

ABSTRACT 
A new crystal form of 10-Propargyl-10-Deazaaminopterin, form SL, was discovered which is thermodynamically stable, shows long term stability and is applicable for using in final dosage forms. Form SL was characterized by several analytical methods such as thermal analysis by DSC, IR, X-ray powder diffraction, SEM (Scanning Electron Microscopy), Digital optical microscopy and solubility/dissolution measurements. Active pharmaceutical ingredients should be stable during technological processes for the preparation of a final dosage form and must also remain stable during storage. The morphology of long needle and plate shaped crystals was investigated by scanning electron microscopy (SEM) and optical microscopy. Form SL was compared to other forms of 10-Propargyl-10-Deazaaminopterin such as form A, B, C and to the amorphous form. The thermodynamic stability of form SL is supported by its long-term stability. Form SL is a pharmaceutically applicable crystal form.

HLL Lifecare Limited, a Mini Ratna Central Public Sector Enterprise under the Ministry of Health & Family Welfare is a global provider of high quality healthcare products & services. Healthcare Services & Pharma Retail Business Divisions of HLL Lifecare Limited has setup Medical Laboratory services and AMRIT Pharmacies respectively across Maharashtra state for which the company is looking for dynamic and performance driven professionals for the following position on Fixed Tenure Contract basis.

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ABOUT AUTHOR
JY Manure, NS Naikwade
Department Of Pharmaceutical Chemistry
Appasaheb Birnale College of Pharmacy,
Sangli, Maharashtra, India
Javeedmanure.98600@yahoo.com

ABSTRACT 
Cancer is a diseases characterized by out-of-control cell growth. There are various types of cancer, and is classified by the type of cell that is affected. Cancer harms the body when altered cells divide uncontrollably to form lumps or masses of tissue called tumors. The recent treatments include chemotherapy, radiotherapy and Surgery. But this treatment accomplished by several side effect like the destruction of bone marrow cell, alopecia etc. So there is a need for the new drug for treatment of cancer. Plant-derived chemical may act as anticancer in many studies. The Plant produces secondary metabolites which are being evaluated for the anticancer activities leading to the development of new drugs. So in this review we have study different plants which act as anticancer. And this will encourage further scientific study of traditionally used plants.

It is an institution formed to the memory of sahkar prabhodhankar late shri Gulabrao Patil by his son Shri Prithviraj Patil. The purpose of the trust is to bring about a revolution in the lives of the rural poor of the area & district by bringing to them the best of schools & Colleges, catering to their diverse needs from languages to information Technology & medicine to Nursing. The Trust & it’s institutes are not only important milestone but a tribute to the vision of shri Gulabrao Patil.

About the College
Rajarambapu College of Pharmacy is a pioneer college catering pharmacy educational needs of the students and society. The college is conducting D. Pharm, B. Pharm and M. Pharm courses (Pharmaceutics, Quality Assurance and Pharmaceutical Chemistry) and Ph D. programme. The college has qualified and experienced staff, well developed library & spacious laboratories. The RCP is approved by DTE, AICTE, Shivaji University, Kop. and PCI. The college is recognized by UGC under 2(f) and 12(b) and permanently affiliated to Shivaji University, Kolhapur.

Karnataka Antibiotics & Pharmaceuticals Ltd., (KAPL) Bangalore is a Government Enterprise.  From a modest beginning in 1984, KAPL has grown from strength to strength in the areas of manufacturing and marketing of various life saving and essential drugs. With an ISO accredition from KPMG, Netherlands, KAPL is recognised for its total commitment to quality and services in domestic and international markets. On profit from inception, KAPL facilities are approved by many international clients.

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ABOUT AUTHORS:
Rajmahamad H. Shaikh¹*, Mohsin J. Jamadar¹, Amol D. Patil¹, Audumbar D. Mali², Sanauaha M.Tamboli^1
1Department of Pharmaceutics, Appasaheb Birnale college of Pharmacy, Sangali, Maharashtra, India.
²Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade, Sangola-413307, Solapur, Maharashtra, India
rajshaikh71@gmail.com

ABSTRACT:
The purpose of this investigation was to enhancement of solubility of cinnarizine by using solid dispersion technique solvent evaporation method using polymer PEG 6000 & develop combination ODT of cinnarizine with domperidone by using direct compression technique using crospovidone, croscarmellose sodium and sodium starch glycolateas a superdisintegrants. The preformulation study includes the compatability of drugs with the polymers by using FTIR,UV,TLC. The batches were evaluated for weight variation, hardness, friability, drug content, wetting time, IN In-vitro dispersion, in-vitro dissolution. The formulation F2 which contain 8% crospovidone and 10 % sodium starch glycolate showed best results and rapid in-vitro dissolution. The results revealed that the tablets containing superdisintegrants combination had a good dissolution profile. The drug content of all the batches was within the acceptable limits of the United States Pharmacopoeia with maximum drug being released at all timeintervals. The present study demonstrated potentials for rapidabsorption, improved bioavailability, effective therapy and patientcompliance. The results conclusively demonstrate successful enhancement of solubility, disintegration and dissolution of the formulated tablets.

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The district of Sangli is a recent creation made as late as in 1949. It was then known as South Satara and it has been renamed as Sangli since 1961. It is partly made up of a few talukas which once formed part of the old Satara district and partly of the States and jagirs belonging to Patvardhans, and Dafles which came to be merged during the post-independence period.

Post: Pharmacist