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Young blood can rejuvenates the brain

 

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(6th May, 2014); The amazing research from UC San Francisco scientist concluded that young blood can rejuvenate brain of aged mice which rooting hopes that new precursors may be identified to come up with advanced aging solution.

Villeda collaborated with scientists at Stanford University for mentioned research which reported that exposure of an old animal to young blood can counteract and reverse pre-existing effects of brain aging at the molecular, structural, functional and cognitive level. The research findings were published in Nature Medicine on May 4.

Scientists identified, a structure in aged mice, cyclic AMP response element binding protein (Creb) in hippocampus region of brain. The activation of Creb by young blood plasma is leads to improvement in age-related cognitive impairments in both contextual fear conditioning and spatial learning and memory.

Villeda said, “We know that something in the young blood leads to Creb activation, and the Creb is a master regulator of gene activity in the brain that is associated with the formation of new connections between neurons underlying learning and memory, adding that Creb activation is known to decrease in both normal human aging and in Alzheimer’s disease."


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