Ph.D

NIMS Institute of Pharmacy is approved by AICTE (All India Council for technical Education), Government of India. It offers undergraduate, postgraduate and Ph. D. programmes. The Institute has its separate building in the campus with spacious well equipped laboratories for each discipline and specialization. Pharma D. course has been designed on the lines of some universities in USA.

National Institute for Research in Reproductive Health (NIRRH), formerly known as Institute for Research in Reproduction is a premier research institute of the Indian Council of Medical Research (ICMR). It is situated in the vicinity of a number of hospitals and research institutes in central Mumbai.

About Authors:
S.Kameshwaran^1*, V.Suresh¹, M.Mohanraj^2
1Department of pharmacology,
JKK munirajah medical research foundation and College of Pharmacy,
B.Komarapalayam, Namakkal, Tamilnadu - 638183
²Marineboitoxinology labs, CAS in marine biology, Annamalai university,
Chidambaram, Tamilnadu-608502
*kamesh.pharm@gmail.com

ABSTRACT
Tecoma stans flowers have been traditionally used for many ailments including cancer. In the present study, anti cancer activity of methanolic flower extract of T.stans (METS) was evaluated using both in vitro and in vivo methods. METS was subjected to preliminary qualitative phytochemical investigations by using standard procedures. In vitro antitumor activity of METS was evaluated by the MTT assay methodusing Vero and HEP-2 cell lines. Then the extract subjected to in vivo anti cancer activity using Ehrlich ascites carcinoma (EAC) tumor model. The activity was assessed Increase in life span, average increase in body weight, changes in food intake, tumor volume, tumor weight, viable cell count, non viable cell count, PCV, Total cell count and hematological studies. The potency of the extract was compared with standard 5-flurouracil (20 mg/kg i.p.).In in vitro anti cancer activity METS exhibited significant cytotoxic activity against both cell lines even at different concentrations. Oral administration of METS at the dose of 200 and 400 mg/Kg, significantly (p < 0.001) increased the survival time, non viable cell count and decreased the average body weight and food intake, viable cell count of the tumor bearing mice. After 14 days of inoculation, METS was able to reverse the changes in the hematological parameters, protein and PCV consequent to tumor inoculation.The results indicate that METS possess significant antitumor activity on dose dependent manner.

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The foundation of Dr B. R. Ambedkar University (originally known as Agra University) was laid on the 1st of July, 1927, as a result of hectic efforts of a band of enthusiastic educationists like Rev. Canon A.W. Davis, Munshi Narain Prasad Asthana, Dr L.P. Mathur, Lala Dewan Chand, Rai Bahadur Anand Swaroop and Dr Brajendra Swaroop,.

KAMLA NEHRU INSTITUTE OF TECHNOLOGY (KNIT) SULTANPUR, was established by Govt. of Uttar Pradesh as a registered society in 1979 with a mission to advanced knowledge and educate students in Engineering & Technology and other areas of scholarship that will best serve the region and the nation. Initially institute was named as Kamla Nehru Institute of Science & Technology (Technological faculty) which was changed to KAMLA NEHRU INSTITUTE OF TECHNOLOGY, SULTANPUR in 1983.

The Jaypee Group, with an annual turnover of over 6500 Crores (US$ 1.5b), is an infrastructure conglomerate with a strong belief in the country’s huge potential. The Group’s business interests are in Engineering & Construction, Power, Cement, Expressways, Real Estate, Hospitality and Education (not for profit). The group companies have been well entrenched in infrastructure projects for over four decades.