Shri Pethaljibhai Chavda is a leading educationalist and industrialist of Junagadh district who has devoted his life for the pious purpose of providing education and 'Sanskaras' to the future of the country. As he strongly believes that education echoes the moral and knowledge of the country. He has dedicated the best of his life years for the development of the education and made efforts to embody values in the students.

About Author:
Brijesh Borad,
The University of London Metropolitan University,
London, UK
borad_brijesh@yahoo.com

Abstract :-
Breast cancer is widely spreaded type of cancer in women and responsible for high number of cancer death in women. Taxol has been already approved to be used for breast cancer by FDA. There have been several studies on the anti tumor activities of Vitamin E Succinate (VES) as complementary and alternative medicine. In present study, we investigated the cytotoxic effect of taxol-VES combination on MCF-7 breast cancer cell lines in comparison with taxol alone. MCF-7 cells are preffered because of higher sensitivity to estogens. MCF-7 cells were sub cultured in according to specifications of aseptic conditions by incubating at 37^οC and 5%CO2. Cells were seeded in 24 well plate with culture medium and different concentration of different drug regimen ( taxol alone, VES alone, taxol-VES combination) for 72hrs. Cell viability can be checked by MTT cell viability assay. MTT assay uses a MTT dye which acts as a substrate for viable cell reductase enzyme. This enzyme reduces MTT yellow dye to purple colour formazan which is in proportional to viable cell eventually. The intensity of purple colour was measured by measuring absorbances at 570nM using spectrophotometer. The results of the study were plotted as %cell viability Vs concentration for each of three drug regimen. IC50 values for each drugs were calculated. Graphical and statistical analysis of results concluded that taxol-MCF combination has more inhibitory effect on MCF-7 breast cancer cell lines when treated for 72hrs in comparison with taxol alone and statistical analysis had concluded that results were significant enough to accept clinically to use in stratagic breast cancer therapy management.

Dr. Reddy's Laboratories (NYSE: RDY) is an emerging global pharmaceutical company with proven research capabilities. The company is vertically integrated with a presence across the pharmaceutical value chain. It produces finished dosage forms, active pharmaceutical ingredients and biotechnology products and markets them globally, with focus on India, US, Europe and Russia.

Birla Institute of

a.Quality control of crude drugs material, plant preparations and finished products.
b.Stability assessment and shelf life.
c.Safety assessment; documentation of safety based on experience or toxicological studies.
d. Assessment of efficacy by ethnomedical informations and biological activity evaluations.

About Authors:
SINGH GAURAV^*, GOKULAN DR P.D., KINIKAR DHANANJAY, KUSHWAH MANOJ
Shri Ramnath Singh Institute Of Pharmaceutical Science and Technology,
Sitholi, Gwalior, M.P
*gaurav.robby@gmail.com

ABSTRACT
Glibenclamide is an oral hypoglycemic drug with very low aqueous solubility. The drug is completely metabolized in liver, its principle metabolite being very weakly active, buccal film may be more efficacious for the treatment of diabetes. The objective of this work is to investigate the feasibility of obtaining the slow release, obtaining relatively constant levels of Glibenclamide from buccal films. The films were fabricated by solvent casting technique with different polymers HPMC, Sodium CMC and PVP and systematically evaluated for in vitro and ex vivo performance. Propylene Glycol is employed as plasticizer and penetration enhancer. Hydroxypropyl methyl cellulose is acting as film forming polymer, Sodium CMC and PVP are employed as mucoadhesive polymer.  The formulation containing HPMC and Sodium CMC (F2) showed better controlled results correlated with ex vivo permeation studies.

National Institute of Nutrition (NIN) was founded by Sir Robert McCarrison in the year 1918 as ‘Beri-Beri’ Enquiry Unit in a single room laboratory at the Pasteur Institute, Coonoor, Tamil Nadu. Within a short span of seven years, this unit blossomed into a "Deficiency Disease Enquiry" and later in 1928, emerged as full-fledged "Nutrition Research Laboratories" (NRL) with Dr.

The Himalaya Drug Company was founded in 1930 by Mr. M. Manal with a clear vision to bring Ayurveda to society in a contemporary form and to unravel the mystery behind the 5,000 year old system of medicine. This included referring to ancient ayurvedic texts, selecting indigenous herbs and subjecting the formulations to modern pharmacological, toxicological and safety tests to create new drugs and therapies.

Banaras Hindu University ranks among the first few in the country in the field of academic and research output.

Apex is a people based organization and its strengths flow from its people. Apex is among the ‘top 50 fastest growing Indian pharma companies’, with most of its products enjoying leadership position in their segments. The company has ambitious plans to expand its product portfolio and expand its reach in the international market.

About Authors:
Piyush Gupta*
Department of Pharmaceutics,
Regional College of Pharmacy,
Jaipur, Rajasthan

ABSTRACT:-
The term MICROSPHERE is defined as a spherical particle with size varying from 50nm to 2µm, containing a core substance. Microspheres are, in strict sense, spherical empty particles.However, the terms microspheres and microencapsulationare used synonymously. In addition, some related terms are “beads” are used alternatively. Spheres and spherical particles are also usedfor a large size and rigid morphology. The microspheres are characteristically free flowing powders consisting of proteins orsynthetic polymers, which are biodegradable in nature, andideally having a particle size less than 200 micrometer. Novel Drug Delivery Systems are developed to address the challengesof drug development such as Bioavailability, Permeability & Poor solubility. These demand changes in the conventional use of Excipients, the growth of the Biotechnology industry,including Stem cell therapy,Vaccines & Genetic products, also necessitates different drug delivery requirements, there by demonstrating the acceptance of these excipients by the US food & drug administration or other agencies in the major markets.For materials in which Toxicity is a possible concern, formulators can give information about the excipients regulatory acceptance& allowable amount by consulting with excipients manufactures& toxicology experts.

Cipla known for its innovative pharmaceutical products backed by latest in technology and creative marketing practices, is enjoying a commanding position among the top pharma companies in the country.
Several specialised therapeutic divisions and promising new products have been launched and many more are in the pipeline.

February 2012

Kerala Forest Research Institute (KFRI) is a leading organization in the field of research in tropical forestry, biodiversity and sustainable bioresource utilization. To consolidate our position and to prepare for the emerging challenges in these areas, we invite dynamic and talented Scientists who are actively pursuing research in selected disciplines, to join our team. KFRI offers the CSIR scales of pay (Scientist B: Rs. 15600-39100 + grade pay Rs. 5,400/- and Scientist-E1 Rs. 15600-39100 + grade pay Rs.

BHAILAL AMIN GENERAL HOSPITAL, VADODARA, GUJARAT is an 'ISO 9001:2000' certified hospital and has turned more special with all the health-care amenities 'under one roof'.

Quintiles is the only fully integrated biopharmaceutical services company offering clinical, commercial, consulting and capital solutions worldwide. Our network of 23,000 engaged professionals in 60 countries around the globe works with an unwavering commitment to patients, safety and ethics — ensuring a higher level of healthcare for people.