Kalol Institute of Pharmacy was established in 2007 as self financed college for B.Pharm course with 60 Intake. The college is spread over 2 acres of land as a part of KIRC campus at Kalol.

About Authors:
Bishal Khatiwada^1,2, Binita Dhakal^1,2, Surya Prasad Sharma^1,2, Uddhav Timilsina¹
1. Department of Biotechnology,
College for Professional Studies, Kathmandu, Nepal
2. Department of Biotechnology,
Sikkim Manipal University, Gangtok, Sikkim, India
*suryapdsharma@gmail.com

Reference Id: PHARMATUTOR-ART-1310

INTRODUCTION
Diabetes mellitus is a metabolic disorder in which person is characterized by the high blood sugar either because the body does not produce enough insulin, or because cells do not use the insulin that is produced.^[1] The classical symptoms of diabetes are polyuria (frequent urination), polydipsia (increased thirst) and polyphagia (increased hunger).^[2] Almost one in 10 of the world population already has this condition, or can be expected to develop it during their lifetime, with prevalence rates forecast to double within the next 15 years.^[3] According to WHO(2000A.D.), at least 171 million people worldwide suffer from diabetes, or 2.8% of the population.^[4]

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Dr. Reddy's Laboratories (NYSE: RDY) is an emerging global pharmaceutical company with proven research capabilities. The company is vertically integrated with a presence across the pharmaceutical value chain. It produces finished dosage forms, active pharmaceutical ingredients and biotechnology products and markets them globally, with focus on India, US, Europe and Russia.

Kemwell Pvt Ltd., established in the year 1972 at Bangalore, Specializes in contract manufacturing for pharmaceutical formulations for various reputed multinations in India. For its expansion plans is looking for yound dynamic personnel.

Post: Manager - Formulation, R&D, QA

The Department of AYUSH, Ministry of Health & Family Welfare, GOI has sanctioned a proposal for “Centre of Excellence in Dravyaguna and Medicinal Plants at Research Institute in ISM, Joginder Nagar, Distt. Mandi” submitted by the Department of Ayurveda amounting to Rs. 5.00 crore. The Society for Development of Vanaspati Van, H.P. has been identified as executing agency of this project.

OIL & NATURAL GAS CORPORATION, Western Onshore Basin, Vadodara wishes to engage suitable interested candidates for the following positions on full time contract basis for its Dispensary for a period of two years w.e.f.01.07.2012 to 30.06.2014. Job is purely on Contractual basis and doesn’t carry any liability on ONGC for regular appointment at any stage.

Ontop Pharmaceuticals, New Delhi, is a established house in the field of pharmaceutical manufacturing with many a path breaking innovations to its credit. The company is envisaging a foray into the marketing of premium functional cosmetics. For this venture the company requires diligent, imaginative & result oriented;

Post: Product Managers

About Authors:
Richa Thakur^*, Gaurav Swami, M.S. Rathore, A.K. Sharma
CT Institute of Pharmaceutical Sciences,
Jalandhar, Punjab, India
*thakur.richa89@gmail.com

ABSTRACT
The anatomy, physiology and biochemistry of the eye render this organ exquisitely impervious to foreign substances. The main challenge to the formulator is to circumvent the protective barriers of the eye without causing permanent tissue damage. The newly developed particulate and vesicular systems like liposomes, pharmacosomes and discosomes are useful in delivering the drug for a longer extent and helpful in reaching the systemic circulation. The most recent advancements of the ocular delivery systems provide the delivery of the genes and proteins to the internal structures which were once inaccessible and thus are of great importance in treating the diseases which are caused due to genetic mutation, failure in normal homeostasis, malignancy but also maintaining the physiological function of eye. The review focuses on the developments achieved in this mode of delivery of the drugs along with the pros and cons associated with greater focus on the advanced delivery systems.

ONGC ranks as the Numero Uno Oil & Gas Exploration & Production (E&P) Company in the world, as per Platts 250 Global Energy Companies List for the year 2008 based on assets, revenues, profits and return on invested capital (ROIC).
ONGC ranks 20th among the Global publicly-listed Energy companies as per ‘PFC Energy 50”

Cipla known for its innovative pharmaceutical products backed by latest in technology and creative marketing practices, is enjoying a commanding position among the top pharma companies in the country.
Several specialised therapeutic divisions and promising new products have been launched and many more are in the pipeline.

Guardian Pharmacy is a six-year-old retail chain of Pharmacy, Wellness, Health and Beauty Stores.

The Himalaya Drug Company was founded in 1930 by Mr. M. Manal with a clear vision to bring Ayurveda to society in a contemporary form and to unravel the mystery behind the 5,000 year old system of medicine. This included referring to ancient ayurvedic texts, selecting indigenous herbs and subjecting the formulations to modern pharmacological, toxicological and safety tests to create new drugs and therapies.

Syngene International is one of India’s premier contract research and manufacturing organizations in providing customized service. Our services encompasses all across discovery chain: early stage discovery, process development, cGMP manufacturing and formulation development both in the small molecule and novel biologics area.

ABOUT AUTHORS:
Renu Singh^*, Saumya Das, Sanjita Das
Institute of Pharmaceutical Technology, NIET,
Greater Noida, U.P., 201306.
*renusingh2910@gmail.com

ABSTRACT
Cognitive deficits have long been recognized as severe and consistent neurological disorders associated with numerous psychiatric and neurodegenerative states such as Alzheimer’s disease. Dementia is one of the age-related mental problems, and a characteristic symptom of Alzheimer’s disease. Alzheimer’s disease (AD) is a progressive neurodegerative disorder which affects older individuals and may progress to a totally vegetative state. Atrophy of cortical and sub-cortical areas is associated with deposition of β-amyloid protein in the form of senile plaques and formation of neurofibrillary tangles. There is marked cholinergic deficiency in the brain, though other neurotransmitter systems are also affected. Various measures to augement cholinergic transmitter in the brain have been tried. The relatively cerebroselective anti-ChEs have been approved for clinical use. Nootropic agents are clinically used in situations where there is organic disorder in learning abilities and for improving memory, mood and behavior, but the resulting side-effects associated with these agents have made their utility limited. Many experimental models are currently available for the evaluation of agents that affect learning and memory processes. In-vitro methods inhibition of acetylcholinesterase activity is measured by determining IC50 with the help of Log probit analysis. In ex-vivo cholinesterase inhibition method the dose response relationship determined for drugs such as physostigmine and tacrine Agents which are H3 receptor agonist are evaluated for [3H] Ach release activity in rat using rat brain slices. The binding affinity of potential nicotinic cholinergic agonist in brain using agonist ligand is determined by [3H]-N- methyl carbamylcholine binding nicotinic cholinergic receptors in rat frontal cortex. In In-vivo methods the inhibitory passive avoidance the test are carried on animals to test the learning and memory capacity of animal by suppressing a particular behavior. It includes step down, step through, two compartment test, up-hill avoidance, scopolamine induced test, and ischemia induced amnesia, memory impairments in basal forebrain. In active avoidance conditioned stimulus is given to the animal, which gives noxious stimulus as a result. It includes runway avoidance, shuttle box avoidance, jumping avoidance. In discrimination learning animals have no choice between the conditioned stimuli. Studies on aged monkeys provides additional advantage for neurobehavioral animal model of aging in that many of behavioral processes thought to be affected by aging.

The Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) is the new state-of-the-art R&D satellite of the Tata Memorial Centre (TMC), which also includes under its umbrella the Tata Memorial Hospital (TMH), the largest cancer hospital in Asia. ACTREC has the mandate to function as a national centre for treatment, research and education in cancer.

Emcure is one of the most progressive Pharma companies with a spectacular track record. Our indigenous chiral molecules and our brands like Orofer-XT, Asomex, Metpure XL are synonymous with Anaemia Management & Hypertension respectively & we have attained leadership position amongst Calcium Channel blockers.

Health biotech is a company that promises good health for all by providing quality medicines at affordable prices and committed to care the people for keeping good health. Health Biotech has won many accolades in the domestic and international pharmaceutical domain.

Titan Biotech Limited, established in 1992, has its state-of-the-art technology at Bhiwadi, Rajasthan-60 k.m. away from Indira Gandhi International Airport ,Delhi , India.

Established in the year 1978 as an exclusive facility for Small Volume Parenterals (SVPs), Gland Pharma has developed into a progressive and quality conscious organization serving the pharmaceutical needs of diverse markets across the globe.
The Company has world-class & world-scale facilities for injectables set up in collaboration with Vetter Group, Germany. The collaboration with Vetter provides Gland Pharma a technological edge in injectables and specifically in Pre Filled Syringes.