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  • A SHORT REVIEW ON POTENTIAL ACTIVITIES OF BENZIMIDAZOLE DERIVATIVES

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    ABOUT AUTHOR:
    Balram Soni*
    Psychiatric Centre, S.M.S. Medical College,
    Jaipur, Rajasthan, India
    brpharma@rediffmail.com

    ABSTRACT
    Benzimidazole derivatives have shown hopeful activity in the treatment of several diseases, for this reason, the synthesis of novel benzimidazole remains a main focus for researchers. This review article summarizes the chemistry of different derivatives of benzimidazole along with their biological activities. The review article also covers the most active benzimidazole derivatives that have shown considerable pharmacological actions.

  • A REVIEW ON IMMEDIATE RELEASE DRUG DELIVERY SYSTEMS

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    ABOUT AUTHORS:
    Mohalkar Rahul1*, Poul Bhagwat2, Patil S.S1, Shetkar M.A1, Dilip Chavan1
    1 Department of Quality Assurance, Maharashtra College of Pharmacy, Nilanga
    2 Principal of Maharashtra College of Pharmacy, Nilanga,
    Latur, Maharashtra, India.
    *rahulmohalkar@gmail.com

    ABSTRACT:
    The oral drug delivery system which includes the solid dosages form such as conventional dosages form and immediate release dosages form. Form last several decades conventional dosage forms like capsule, solid, pills, powder, solution, emulsion, suspension aerosols are used in the various treatments of acute or chronic disease. Today this formulation can be considered as primary pharmaceutical product are mostly seen in overalls market. Tablet is most popular among the all dosages forms today and recently found mostly accepted tablet dosages forms. Because of its convenience easy to administration, convenience of self administration, compactness and easy for the manufacturing. In number of cases immediate onset of action is required than conventional therapy. The basic approach used in development immediate release solid dosages form by using superdisintegrant like sodium starch glycolate (Primogel, Explotab), Polyvinylpyrrolidone (PVP) etc. which provides in instantaneous disintegration of tablet after administration. By using various techniques in can be formulate like wet granulation, direct compression etc. Hence its having A new dosage form allows a manufacturer to extend market exclusivity, while offering its patient population a more convenient dosage form or dosing regimen.

  • REVIEW ON STABILITY INDICATING ASSAY METHODS (SIAMS)
  • COMPARATIVE EVALUATION OF PURIFICATION METHODS FOR PRODUCTION OF POLYPEPTIDE ANTIBIOTICS – POLYMYXIN B AND CEREXIN A FROM BACILLUS SPECIES
  • EVALUATION OF ANTI-DEPRESSANT ACTIVITY OF HYDRO ALCOHOLIC EXTRACT OF TRITICUM AESTIVUM

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    ABOUT AUTHORS:
    K.Charan
    A.U.College of Pharmaceutical Sciences,
    Waltair, Visakhapatnam, Andhra Pradesh, India.
    charan.karumuri@gmail.com

    ABSTRACT
    The present study was designed to screen anti-depressant activity of Hydro alcoholic extract of Triticum Aestivum using Chronic models (14 day study) of Tail suspension test (TST) and Forced Swim Test (FST) in Swiss Albino rats. Wheat grass were collected and authenticated. Extraction of dried wheat grass was carried out using a Soxhlet apparatus to obtain its Hydro alcoholic extract. The extract of Triticum Aestivum showed the significant anti-depressant activity comparable to the standard drug. The oral administration of Triticum Aestivum extract at doses 200 mg/kg & 400 mg/kg respectively as compared to the control treated group showed an anti-depressant activity comparable to that of standard drug.
    The anti-depressant effects of Triticum Aestivum extract seem to be mainly associated with the activation of dopaminergic system and possess potential anti-depressant activity.

  • ANTI-CANCER (NOVEL AGENTS): A REVIEW

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    ABOUT AUTHORS:
    V. Sravanthi*, Mayure vijay kumar, G.J.Finny, C.P.Meher
    Department of pharmaceutical chemistry, Maheshwara College of Pharmacy
    Isnapur chitkul ‘X’ road, Patancheru, Hyderabad-502307
    *v.sravanthi27@gmail.com

    ABSTRACT:
    Cancer is a class of diseases characterized by out-of-control cell growth. Cancer cells damage the body by multiplying their cells uncontrollably to form masses of tissue named as tumor. Tumors cells can grow and interfere with the digestive, nervous, and circulatory systems, and they can release hormones that alter body function. Tumors that are severe to body are called cancerous tumors, and temporary cells that are affected to body are not harmful and called as benign tumors. Nearly 100’s of cancers are known to be effecting the humans. According to this concern the presented review outlines the novel anticancer agents how they are useful, their mechanism, and chemistry has briefly discussed in this article, the main aim of these review is to evaluate the complete novel anticancer drugs under single review paper.

  • RAPID AND SELECTIVE UV SPECTROPHOTOMETRIC AND RP-HPLC METHODS FOR DISSOLUTION STUDIES OF IVABRADINE CONTROLLED-RELEASE FORMULATIONS
  • IN VITRO EVALUATION OF ANTACID POTENTIAL OF CURCUMA LONGA LINN
  • REVIEW ON DEVELOPMENT OF ORPHAN DRUG FOR RARE DISEASE
  • EVALUATION OF THE SYNERGIC ANTIPROLIFERATIVE AND CYTOSTATIC EFFECTS OF ANANAS COMOSUS, CITRALLUS LANATUS AND CITRUS SINENSIS JUICE
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