Pharmacognosy Articles

A REVIEW ON ANTI-HIV ACTIVITIES OF COMPOUNDS ISOLATED FROM THE MEDICINAL PLANT AND ADVANTAGE OF PLANT TISSUE CULTURE IN DEVELOPMENT OF ANTI-HIV MEDICINAL PLANTS

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About Authors:
1Amita Pandey,2Dr. Shalini Tripathi
1Research student of Rameshwaram Institute of Technology and Management, Sitapur Road, Lucknow (U.P.)
2Professor of Rameshwaram Institute of Technology and Management, Sitapur Road, Lucknow (U.P.)
pandey.amita2012@gmail.com

Abstract
The AIDS pandemic is one of the most disastrous health and development issue in our world today. Tissue culturing of medicinal plants is widely used to produce active compounds for herbal and pharmaceutical industries. Natural products provide a large reservoir for screening of anti-HIV agents with novel structure and anti-viral mechanism because of their structural diversity. This work reviews in vitro micro propagation techniques and gives examples of various commercially important medicinal plants. Advantages-To produce many copies in any time of the same plants then which may be used to produce plants with better flowers, odour’s, fruits or any other properties of the plants that is beneficial to the human beings. Conclusion- HIV is the most common untreated word wide disease in now a days and Plant tissue culture is most important technique for growing new plant species in proper aseptic condition which are useful for the cure of HIV. Acknowledgement- I would like to record my gratitude to my esteemed respected guide Dr. (Prof.) ShaliniTripathi, Department of Pharmacy, Rameshwaram Institute of Technology and Management

PRELIMINARY ASSESSMENT OF THE ANTIPROLIFERATIVE POTENTIAL OF THE HERBAL FORMULA "EKPO AGANWO"

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About Authors:
Enegide Chinedu*, David Arome, Solomon Fidelis Ameh
Department of Science Laboratory Technology (Physiology & Pharmacology Technology),
University of Jos, Jos Nigeria
chinex.snow@gmail.com

Abstract
Background:
Cancer is a major global public health problem and has metamorphosed to a leading cause of death globally. Latest predictions by the Word Health Organization suggest that cancer death rate may escalate to about 15 million deaths by 2030. Though various anticancer agents have been discovered and are in use currently, they have not been able to tame the disease effectively. This has left the scientific community with the task of discovering/developing better agents with high efficacy and minimal adverse effect. There have been increased interests by both developed countries and the scientific community towards the importance of herbs as a fountainhead in the development of newer drugs, as many classes of drugs now in use contain models from natual product. Ekpo aganwo (EA) is an herbal formulation prepared from the stem bark of Khaya senegalensis and is its main constituent.
Aim:
This study was design as a preliminary assessment of the antiproliferative potential of EA.
Materials and Method:
The modified Ayinde et al., bench top assay method was employed for the study.
Result:
Methotrexate compared with control, caused a significant (P<0.05) decrease in radicle lenght throughout the study. The percentage inhibition was however highest after 72 hours, with a rate of 86.67%. EA 10 mg/ml did not produce any significant decrease in radicle growth after 48 hours, but however showed a significant (P<0.05) decrease in radicle growth after 72 hours of experiment. The percentage inhibition after 72 hours was 24.56%. EA doses of 20 - 100 mg/ml produced significant (P<0.05) decrease in radicle growth throughout the experiment. The percentage inhbition of EA doses of 20 - 100 mg/ml was 28.07 - 59.65 % after 72 hours.
Conclusion: The results obtained have favoured the postulation of EA having an anticancer potential, and this have been supported by the significant antiproliferative activity it produced during the experiment.

Require faculty positions in Nirma University | Need of Bachelors and Masters Degree in Pharmacy

Nirma University is a statutory University established under the State Act and recognized by University Grants commission u/s. 2(f) of UGC Act. It has Institute of Technology, Pharmacy, Management, Science and Law catering the need of imparting education from Bachelor to Ph.D. in different fields and conducting research.

The University invites applications for the existing and future following positions:

Post: Professor, Associate Professor, Assistant Professor

MUSK MELON: MINERALS, NUTRITIONAL VALUES

ABOUT AUTHORS:
Kambham Venkateswarlu1*, N.Devann2, R.Venu Priya3, P.Bharath Rathna Kumar4
1M.Pharm Scholar, Department Of Pharmaceutics,
2Director Of Jntua-Otri,
3Faculty Of Pharmacy, Department Of Pharmaceutics,
4Faculty Of Pharmacy, Department Of Pharmaceutical Chemistry,
JNTUA-Oil Technological Research Institute,
Beside Collector Office, Anantapur, Anantapur District, Andhra Pradesh, India. Pin Code: 515001
*k.v.reddy9441701016@gmail.com

ABSTRACT:
Muskmelon (Cucumismelo L) is a representative of cucumber (Cucurbitaceous) family. Muskmelon is also known as “Nut meg” melons. The name is derived from the Romans habit of sprinkling the fruit with powdered musk to accentuate the flavour (White man and Mayhew – 1998) the word ‘Musk’ is derived from Persian literature which means “Perfume” and other word “melon” is fresh from the latinMelopepo meaning “apple-shaped melon”.

This review will give the optimum information about minerals, nutritional values of musk melon.

REVIEW ON ‘HIBISCUS SABDARIFFA’

ABOUT AUTHORS:
Kambham Venkateswarlu1*, N.Devanna2, Bukke Nirmala3, Katipogu Sandhyarani4
1M.Pharm Scholar, Department Of Pharmaceutics,
2Director Of JNTUA-Otri,
3M.Pharm Scholar, Department Of Pharmaceutical Analysis
JNTUA-Oil Technological Research Institute,
Beside Collector Office, Anantapur, Anantapur District, Andhra Pradesh, India. Pin Code: 515001
*k.v.reddy9441701016@gmail.com

ABSTRACT:
This review gives full details about the Hibiscus sabdariffa Linn. This crude drug has a following medicinal uses antiseptic, aphrodisiac, astringent, cholagogue, demulcent, digestive, diuretic, emollient, purgative, refrigerant, resolvent, sedative, stomachic, and tonic. Also gives information about how to cultivate and harvest, in which conditions if we cultivates can get a high yield.

WATERMELON (Citrullus lanatus): A REVIEW

About Authors:
Kambham Venkateswarlu1*, N.Devanna2, Gurrapu Lalitha3, Revanuru Sukanya4
1M.Pharm Scholar, Department Of Pharmaceutics,
2Director Of JNTUA-Otri,
3,4M.Pharm Scholar, Department Of Pharmaceutical Analysis
JNTUA-Oil Technological Research Institute,
Beside Collector Office, Anantapur, Anantapur District, Andhra Pradesh, India. Pin Code: 515001
k.v.reddy9441701016@gmail.com

Abstract:
The aim of this review is to provide information about nutritional values, what are the special considerations should take while harvesting, and world production of Watermelon fruit. Watermelon is an ancient fruit. The ancestors of the watermelon called the Tsamma melon, which are still found in the Kalahari Desert even today. This review alo gives the information about what are the constituents present in the Watermelon fruit.

REVIEW ON ANTI AGING

ABOUT AUTHOR:
Sayoni Sengupta
M.Pharm 1st Sem.
Kanak Manjari Institute of Pharmaceutical Sciences
Rourkela, Orissa
bonirini@hotmail.com

ABSTRACT
Aging is the accumulation of changes in person overtime. Aging in humans refers to a multidimensional process of physical, physiological and social changes.
Recent studies have revealed that certain medicinal herbs are effective in the intervention or prevention of aging and also in the eradication of age associated disorders. Herbs used in anti-aging programmes have medicinal properties which stimulate the vital organs in the body and restore their normal function. Many of them possess antioxidant properties.
Ginseng derived from the Chinese term, belongs to the genus Panax, of the family Araliaceaeby the presence of ginsenoside.
Recent studies explain the exotic role of Panax ginseng’s ginsenoside in promoting neurological health support and also state its beneficial effects in anti-aging and nerve related problems.

GREENER ITINERARY TO THWART PHARMACY - EFFLUENCE

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ABOUT AUTHOR:
Raaz K Maheshwari
Department of Chemistry, SBRM PG Govt College,
Nagaur, Rajasthan
drraazgreenchemacs@gmail.com

ABSTRACT
The use of PPCPs is on the rise on the globe. PPCPs enter into the environment through individual human activity and as residues from manufacturing, agribusiness, veterinary use, and hospital and community use. Individuals may add PPCPs to the environment through waste excretion and bathing as well as by directly disposing of unused medications to septic tanks, sewers, or trash. Because PPCPs tend to dissolve relatively easily and don’t evaporate at normal temperatures, they often end up in soil and water bodies. Some PPCPs are broken down or processed easily by a human or animal body and/or degrade quickly in the environment. However, others do not break down or degrade easily. The likelihood or ease with which an individual substance will break down depends on its chemical makeup and the metabolic pathway of the compound. Varying concentrations of drugs found in water sources can have ill effect on the aquatic life and human health. For pharmaceutical pollution, the solution calls upon all health care sectors to participate in preventing pharmaceutical pollution. Green Pharmacy aims at zero pharmaceutical waste in our environment. It offers an opportunity for social action that will greatly benefit our environment at all levels of our society. It encourages health providers and clients to focus on healthy lifestyle and prevention to ensure their well-being through regular wellness practices. It provides education and opportunity for everyone involved with the life cycle of medicine to participate in reducing pharmaceutical pollution. With relatively simple yet firm commitments to change our habits, becoming stewards of medicine rather than consumers of medicine we effectively become part of the solution. This review paper delineates about the powerful approaches of green pharmacy that provides comprehensive solution to pharmaceutical pollution affecting much of well being on globe. Research to date points to the ubiquity of PPCPs in aquatic environments. Existing wastewater treatment facilities are inadequate and aren’t designed to remove them from the waste stream. Our current system of quantifying their toxicological effects is inadequate. Now is the time to prevent further harm to living organisms and the environment.

PHYTOCHEMICAL ASSESSMENT OF THE AQUEOUS AND METHANOLIC EXTRACTS OF SOME HERBAL PLANTS IN JOS, NIGERIA

About Authors:
Enegide Chinedu*, David Arome, SolomonF. Ameh
Department of Science Laboratory Technology (Physiology & Pharmacology Technology),
University of Jos, Jos Nigeria.
chinex.snow@gmail.com

Abstract
Phytochemicals are referred to as pharmacologically active substances which are naturally present in plants. However, the effects of various plant preparations in the body when administered, is dependent on the phytochemicals present. Herbal medicine have been said to be the oldest form of medicine and have of recent even gained new momentum due to its advantages.The World Health Organization has recognized that traditional herbal plants may be useful in an integrated health care deliverysystem in several countries. But however to achieve the goal of using both herbal medicine and modern medicine paripassu, there is need for the phytochemical assessment of the plants coupled with pharmacological and toxicological investigations as well. Therefore, the aim of this research is to evaluate the phytochemicals present in the aqueous and ethanolic extracts of some herbal plants in Jos, Nigeria. This study have unveiled the presence of various phytochemcals in the different plant extracts examined. The various phytochemicals present in the extracts includes alkaloids, saponins, tanins, flavonoids, carbohydrates, steroids, cardiac glycosides and anthraquinones. These phytochemicals are known to posses therapeutic and also physiological activity. The test have shown that the plants are useful as they contain phytochemicals capable of producing valuable pharmacological effects. However, further studies aimed at establishing the dosage in which the may produce their pharmacological effects and toxicity should be done. Studies aimed at isolating the phytochemicals and screening their individual effects will also be very useful.

HERBAL PLANTS A RELIABLE SOURCE FOR DRUG DISCOVERY AND DEVELOPMENT

About Authors:
Enegide Chinedu*, David Arome, Solomon F. Ameh
Department of Science Laboratory Technology (Physiology & Pharmacology Technology),
University of Jos, Jos Nigeria.
*chinex.snow@gmail.com

Abstract
Though remarkable success have been achieved in the discovery and development of various drugs for the treatment and management of several ailments, there is still need for more discoveries. This is due to the reason that some of the drugs currently in use posseses one or more of the following drawbacks (i) high toxicity level (ii) increase lose of effectiveness or low efficacy (iii) costly or (iv) inaccessable. Herbs have now become the main stream for drug discovery and development. Conservative estimate have revealed that there are over 250,000 higher plant species, and only a minute proportion have been screened exhaustively for their possible therapeutic properties. Atleast, over 120 unique pharmacological substances derived from plants are currently being used as drugs in various countries in the world. Apart from the direct use of plant derivatives as therapeutic agents, they can also serve as models for the design, synthesis or semisynthesis of other therpeutic agents. In conclusion, herbs are a reliable source for more discovery and development of new drugs. The scientific community should therefore harness this resource by improving research on it.

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