• 9 September 2013

    A REVIEW ON NEUROTOXICITY

    About Authors:
    Yogesh Yaduwanshi*, Gireesh Mehta, Jitendra Shakyawal, Surya Pratap, Sanjay Singh, Mahaveer Kabra
    Department of Pharmacology,
    Kota College of Pharmacy, Kota,
    Rajasthan India
    *yogeshyaduwanshi24@gmail.com

    Abstract:
    Chemicals are an integral part of our daily lives and are responsible for substantially improving them. Yet chemicals can also endanger our health, even our survival. This report focuses on neurotoxic substances, those chemicals that adversely affect the nervous system. Included among such substances are industrial chemicals, pesticides, therapeutic drugs, abused drugs, foods, food additives, cosmetic ingredients, and naturally occurring substances. Whether a substance causes an adverse health effect depends on many factors, including the toxicity of the substance, the extent of exposure, and an individual's age and state of health. Minimizing public health risks requires knowledge about the properties and mechanisms of action of potentially toxic substances to which humans may be exposed. The assessment includes discussion of industrial chemicals, pesticides, therapeutic drugs, substance drugs, foods, food additives, cosmetic ingredients, and such naturally occurring substances as lead and mercury. It does not include radioactive chemicals, nicotine, alcohol, biological and chemical warfare agents, microbial, plant, and animal toxins, and physical agents such as noise.

  • DENDRIMER: A NOVEL SYSTEM IN PHARMACEUTICALS
    2 August 2013
    DENDRIMER: A NOVEL SYSTEM IN PHARMACEUTICALS

    ABOUT AUTHORS:
    Abhishek Shah*, Gautam Singhvi
    Department of Pharmacy, Industrial Research Lab,
    Birla Institute of Technology and Science,
    Pilani, Rajasthan, India., Pin: 333 031
    abhishah200291@gmail.com

  • THERAPEUTIC POTENTIAL OF VENOMOUS PEPTIDE IN VARIOUS DISEASES
    5 June 2013
    THERAPEUTIC POTENTIAL OF VENOMOUS PEPTIDE IN VARIOUS DISEASES

    ABOUT AUTHORS:
    1*Anjali Choba, 2Shikha Attri
    1M.Pharma in pharmacology from shoolini university solan, himachal pradesh
    2M.Pharm in pharmaceutical chemistry from lachoo memorial college of science and technology, jodhpur
    *anji5057@yahoo.in

  • NOVEL SYNTHETIC APPROACHES FOR THE TREATMENT OF MALIGNANT MELANOMA UNDER CLINICAL TRIAL
    20 May 2013
    NOVEL SYNTHETIC APPROACHES FOR THE TREATMENT OF MALIGNANT MELANOMA UNDER CLINICAL TRIAL

    ABOUT AUTHORS:
    Tara Shankar Basuri1*, Ishvar Parmar1, Vishal Modi2, Virag Shah3, Niyatee Thakur4
    SSR College of pharmacy, Silvassa,
    U.T of Dadra & Nagar Haveli-396230
    *tbasuri@gmail.com

    ABSTRACT
    Malignant melanoma is the most lethal form of skin cancer and an increasingly common disease worldwide. It remains one of the most treatment-refractory malignancies. The current treatment options for patients with metastatic melanoma are limited and in most cases non-curative. This review focuses on novel synthetic and herbal drugs for malignant melanoma treatment, by a single or combinational agent approach. These molecules are widely used by the oncologists for the treatment of this type of cancer. So this review can help to the public to aware the malignant melanoma and its treatment and novel target for its treatment.

  • ANGIOGENESIS IN MYOCARDIAL ISCHEMIA : AN ORGANIZED REVIEW
    11 March 2013
    ANGIOGENESIS IN MYOCARDIAL ISCHEMIA : AN ORGANIZED REVIEW

    ABOUT AUTHORS:
    Jalaram H Thakkar*, Ashiyana A Mansuri, Chirag Patel, Girish K Jani,
    SSR College of Pharmacy,
    Silvassa    .
    *jay_143143@yahoo.com
    { DOWNLOAD AS PDF }

    ABSTRACT:
    The term Angiogenesis was coined by DR. John Hunter, a British surgeon in 1787. Later professor Judah Folkman gave the idea that growth of tumor depends on their blood supply and a new began research in this new field of therapeutics called ANGIOGENESIS.  Then, the identification of angiogenic growth factors, Vascular Endothelial Growth Factor (VEGF) and Fibroblast Growth Factor (FGF) fueled interest in using these factors in inducing therapeutic angiogenesis.[1] Initially angiogenesis was implicated only in few diseases like cancer, psoriases and arthritis. But, in recent years, it has been evident through a deep research that even excessive, insufficient and abnormal angiogenesis contribute to the pathogenesis of many disorders. Angiogenesis is regulated by a balance between pro- and anti- angiogenic factors. Research shows that angiogenesis and anti angiogenesis has given promising results in treatment of diseases like AIDS, atherosclerosis, ischemic heart disease and Alzheimer’s. In twenty first century, application of angiogenesis in therapeutics may have an impact on disorders similar to that which the discovery of antibiotics had in twentieth century.

  • GREEN BLOOD THERAPY
    28 February 2013
    GREEN BLOOD THERAPY

    About Author:
    Ravi Kant
    B.Pharm
    Maharshi arvind institute of pharmacy, jaipur
    rvkantyadav00@gmail.com

    1. Introduction:-
    Wheat grass consists of carbohydrates, proteins, all essential minerals and vitamins. As wheat grass juice bears a closer resemblance to the " haemogolobin " in our blood, the juice is often called as " green blood" and the therapy using it is called as " green blood therapy" wheat grass juice is complete food. Wheatgrass (baby wheat) juice is an extremely natural food. Since Dr. Anne Wigmore rediscovered the nutritional qualities of wheatgrass juice in 1960, the juice has helped hundreds of thousands of people around the world to overcome serious health problems.

    However wheatgrass juice is not a panacea. If you continue to consume processed foods, drugs, alcohol, tobacco, burned foods and other toxic substances that can make you ill, a few milliliters of wheatgrass juice each day won't make much difference. Instead, try consuming a predominately (or entirely) raw food diet with organic wheatgrass juice. You will most likely experience a world of improvement.

  • NOVEL DRUG DELIVERY SYSTEM
    14 February 2013
    NOVEL DRUG DELIVERY SYSTEM

    About Authors:
    Aruna Rastogi
    Roorkee College of Pharmacy and UTU
    Patanjali Ayurved Ltd, Sr. Chemist
    arunarastogi10@gmail.com

    1.   INTRODUCTION
    1.1 NOVEL DRUG DELIVERY SYSTEM:
    The method by which a drug is delivered can have a significant effect on its efficacy. Some drugs have an optimum concentration range within which maximum benefit is derived, and concentrations above or below this range can be toxic or produce no therapeutic benefit at all. On the other hand, the very slow progress in the efficacy of the treatment of severe diseases, has suggested a growing need for a multidisciplinary approach to the delivery of therapeutics to targets in tissues. From this, new ideas on controlling the pharmacokinetics, pharmacodynamics, non-specific toxicity, immunogenicity, biorecognition, and efficacy of drugs were generated. These new strategies, often called drug delivery systems (DDS), are based on interdisciplinary approaches that combine polymer science, pharmaceutics, bioconjugate chemistry, and molecular biology.

  • I.T.S. Paramedical Pharmacy College invites for AICTE Sponsored seminar on 5th & 6th April 2013 Pharmacovigilance: Regulators, Presepective & Prospects for Risk Management
    13 February 2013
    I.T.S. Paramedical Pharmacy College invites for AICTE Sponsored seminar on 5th & 6th April 2013 Pharmacovigilance: Regulators, Presepective & Prospects for Risk Management

    I.T.S - The Education Group - established in 1995 under the aegis of Durga Charitable Society, is one of the most reputed education groups in the field of Pharmacy, Dentistry, Engineering, Management, Information Technology, Physiotherapy and Biotechnology. I.T.S has shown incessant growth ever since. The Group has 4 campuses, 8 Institutions and 2D courses. The quality of education is incontrovertibly laudable.

  • STANDARDIZATION OF HERBAL DRUGS/PRODUCTS: BOON TO INDIAN PHARMA MARKET
    8 February 2013
    STANDARDIZATION OF HERBAL DRUGS/PRODUCTS: BOON TO INDIAN PHARMA MARKET

    About Author:
    Swati Manik
    Department of Pharmacognosy,
    I.S.F. College of Pharmacy, Moga, Punjab
    swatimanik@yahoo.in

  • NATURALLY OCCURRING MYCOTOXINS – AFLATOXIN
    6 December 2012
    NATURALLY OCCURRING MYCOTOXINS – AFLATOXIN

    About Authors:
    Sahu Deepak*
    Ass. Professor, Geetanjali Institute of Pharmacy,
    Dabok, Udaipur [Rajasthan] – 313022
    deepak.sahu.bhl@gmail.com
    { DOWNLOAD AS PDF }

    Abstract:
    A toxin produced by mold that can damage the liver and may lead to liver cancer. Aflatoxins cause cancer in some animals. The fungi that produce aflatoxin grow on crops such as peanuts (especially) and wheat, corn, beans and rice. Aflatoxin is a problem particularly in undeveloped and developing countries.
    Aflatoxin is a naturally occurring mycotoxin produced by two types of mold: Aspergillus flavus and Aspergillus parasiticus. Aspergillus flavus is common and widespread in nature and is most often found when certain grains are grown under stressful conditions such as drought. The mold occurs in soil, decaying vegetation, hay, and grains undergoing microbiological deterioration and invades all types of organic substrates whenever and wherever the conditions are favorable for its growth. Favorable conditions include high moisture content and high temperature. At least 13 different types of aflatoxin are produced in nature with aflatoxin B1 considered as the most toxic. While the presence of Aspergillus flavus does not always indicate harmful levels of aflatoxin it does mean that the potential for aflatoxin production is present.1,2,3

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