Latur

Post: Pharmacist

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No.of post: 05

Pay Band: 5200- 20200/- Grade pay- 2400/-

Applications are invited through MKCL for filling up applications from eligible candidates for post of pharmacist

Post: Pharmacists

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ABOUT AUTHORS:
Ghodke D.V*, Bhusnure O.G, Kulkarni A.A
Department Of Quality Assurance in Maharashtra College of M .Pharmacy Nilanga.* Dist –Latur
Department Of Medicinal chemistry in Maharashtra College of Pharmacy Nilanga, Dist –Latur
*ghodke.deepa@gmail.com

ABSTRACT
Pharma Industry is facing growing demands for increased productivity and reduced manufacturing costs and also has to meet the evolving need for higher quality standards and higher drug expectations. In traditional approach quality of the raw material attributes both physically and chemically testing was done by off-line process. The application of Process Analytical Technology in pharmaceutical production checks the quality   at-line, in-line or on-line thereby decreasing the chances of contamination and cross contamination. Implementation of Process Analytical Technology to pharma industry increased process understanding and continuous improvement also improve regulatory compliance. PAT involves the use of different technologies and tools to build quality into the products. Effective PAT implementation is based on detailed, science-based understanding of the physical, chemical and mechanical properties of all elements of the proposed drug product. In this article, Process Analytical Technology has been introduced its application different tools have been discussed to ensures quality of the pharmaceutical products.

ABOUT AUTHORS:
Mr. Kulkarni Sarang*,Birajdar Shivprasad M., Shaikh Parvej H., Dr. Poul B.N
Maharashtra College of Pharmacy, Nilanga, dist. Latur (MS) 413521, India
*sarangkulkarni342@gmail.com

ABSTRACT
Oral route is the most preferred route for administration of various drugs because it is regarded as safest, most convenient and economical route. Recently researcher developed the fast disintegrating tablets with improved patient compliance and convenience. Fast disintegrating tablets are solid dosage forms which dissolve rapidly in saliva without chewing and additional water. Fast disintegrating tablets overcome the disadvantages of conventional dosage form especially dysphagia (difficulty in swallowing) in paediatric and geriatric patients. Natural materials have advantages over synthetic ones since they are chemically inert, nontoxic, less expensive, biodegradable and widely available. They can also be modified in different ways to obtain tailor- made materials for drug delivery systems and thus can compete with the available synthetic excipients. With the increasing interest in polymers of natural origin, the pharmaceutical world has compliance to use most of them in their formulations. The natural superdisintegrants can be used instead of synthetic superdisintegrants as they showed equal disintegrating property as that of synthetic agents or dispersible tablets.