Review Articles

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  • PharmaTutor
    9 December 2014

    REVIEW: PLAGIARISM AN ACT OF UNETHICS

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    ABOUT AUTHORS:
    Anuradha Sharma1*, Vaibhav Walia2, Monika Gahlawat3
    1Division of Pharma. Chemistry, 2Division of Pharmacology, 3Division of Pharmaceutics,
    G.V.M. College of Pharmacy,
    Sonepat, Haryana, India
    *anusarswat@gmail.com

    ABSTRACT
    Plagiarism is a multifaceted and ethically a complex problemwhich simply means the stealing and publication of another author’s work as one's own original work without acknowledge the original author. Plagiarism is simply an act of fraud.Authors should acknowledge sources fully and appropriately to follow the ethics and plagiarism is failure to do so. However the students or the authors sometimes fail to acknowledge the source appropriately and properly. These failures are largely due to the lack of knowledge to use the citations properly. Therefore to maintain the ethics the plagiarism should be avoided. The aim of this paper is to define plagiarism, its type, methods of detection and the ways to avoid plagiarism.

  • 26 November 2014
    A REVIEW ON ROLE OF LASER PHOTOCOAGULATION THERAPY IN DIABETIC RETINOPATHY

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    ABOUT AUTHORS:
    M. Sushma*, T. V. V. Vidyadhar, M. Babu M.D., R. Mohan raj
    *Department of Pharmacy Practice,
    Raghavendra Institute of Pharmaceutical Education & Research, RIPER.
    K R Palli Cross, Near S.K University, Anantapuramu District, Andhra Pradesh
    sushma.banthi@gmail.com

    ABSTRACT
    Diabetic retinopathy, one of the leading causes of blindness for diabetic patients between the ages of 20 and 74. The clinical research provides control of blood glucose and blood pressure substantially reduces the risk of blindness due to diabetic retinopathy, many patients develop this eye disease and are at risk for serious vision loss, sometimes even despite outstanding metabolic control. Diabetic retinopathy occurs when high blood glucose damages the micro blood vessels in the retina which leads to leakage of small amounts of blood, serum, blood fats and blood proteins proliferates to vision loss and formation of scar tissue. Here the retinal laser therapy also called aslaser photocoagulation has greatly reduced the number of patients who lose vision to Diabetic retinopathy. Laser photocoagulation refers to the precise and concentrated application of high energy light, typically of a single wavelength called monochromatic light.

  • 11 November 2014
    ROLE OF BCG IN TREATMENT OF BLADDER CANCER

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    ABOUT AUTHOR
    Abhishek Singhal
    Department of Pharmacology,
    Smt. Kashibai Navale College of Pharmacy, Kondhwa (Bk.),
    Pune, Maharastra, India
    *abhishekspharma@gmail.com

    ABSTRACT
    Aim: This review is written to describe the role of immunotherapy in cancer treatment.
    Annually, 13,000 deaths result from bladder cancer. Since the first report of intravesical use of BCG in 1976, investigators try to understand the working mechanism of BCG as an antitumour modality. Arbitrarily, BCG therapy consists of a single course of six weekly intravesical instillations. Bacillus Calmette-Gue´rin, an attenuated strain of Mycobacterium bovis, was developed by Calmette and Gue´rin with the intention to generate a vaccine against tuberculosis. Extension of BCG treatment (maintenance immunotherapy) is used to increase efficacy.
    Results of various experiments describe that after instillation in the bladder, BCG accumulates near the bladder wall and is internalised and processed by professional antigen-presenting cells (APCs) and (high-grade) tumour cells. Then BCG antigens are presented to CD4+ T cells. Then local synthesis of a particular set of cytokines or cell-mediated immune response. NK cells may be involve in tumour cell killing.

  • 9 November 2014
    DEADLY BUT CURABLE: A REVIEW ON POTENTIAL TREATMENTS FOR EBOLA HAEMORRHAGIC FEVER

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    ABOUT AUTHOR:
    Bushra Shamim
    Department of Pharmaceutics,
    Faculty of Pharmacy,
    Hamdard University, New Delhi, India
    bushrashamim21@gmail.com

    ABSTRACT
    This is a review article on potential treatments for Ebola virus disease, also known as Ebola haemorrhagic fever. Ebola fever has emerged as one of the deadliest known forms of hemorrhagic fever since discovered in 1976.  Transmission among humans occurs through the exchange of blood and body secretions. The Ebola virus causes an acute, serious illness which is often fatal if untreated. In this article experimental treatments like blood, immunological and drug therapies are discussed that are under development

  • 27 October 2014
    EFFECT OF MAGNETIC FIELD ON CANCER CELLS

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    ABOUT AUTHORS:
    Rajesh Tiwari1*, Roshan kumar2
    1Chemistry Department, Dr. Ghanshyam Singh Post Graduate College, Varanasi
    2SBCBE VIT University, Vellore
    *Rajesh.tiwari851@gmail.com

    ABSTRACT
    In 16th century physician were of the opinion that magnet can be used for the treatment or eliminate the diseases from the body. Here the reports about the chemical synthesis, protection, functionalization and application of magnetic nanoparticles of nano structured system. Research of magnetic nanoparticles for targeted drug delivery system and function of magnetic nanoparticles on particular area are reviewed. Use of magnetic nanoparticles for cancer diagnosis has been advancing day by day. This review is related to the multifunctional use of magnetic nanoparticles probes and their use in bio imaging and nano medicine.

  • 26 October 2014
    MULTIPLE SCLEROSIS: OVERVIEW ON SIMPLE CURE

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    ABOUT AUTHORS:
    Duvvuru Ashok Kumar1*, Languluri Reddenna2
    1Department of Pharm-D, P. Rami Reddy Memorial College of Pharmacy, Kadapa, Andhra Pradesh, India
    2Department of Pharmacy Practice, Rajiv Gandhi Institute of Medical Sciences, Kadapa, Andhra Pradesh, India
    ashok.alex11@gmail.com

    ABSTRACT
    MS is the most common inflammatory-demyelinating disease of the central nervous system (CNS). MS is estimated to affect 400,000 persons in the United States and 2 million people worldwide. Women are affected twice as frequently as men, between the ages of 20 and 40. The etiology of MS is still unknown, but according to current data the disease develops in genetically susceptible individuals and may require additional environmental triggers. In this paper, we present the insight on simple cure for multiple sclerosis.

  • 22 October 2014
    HERBAL ANTI HYPERTENSION DRUGS

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    ABOUT AUTHORS:
    Asha Kesari*, Pushpa Kumari Mahto, Shankheswari Kishan, Suranjeeta Singh
    Department of Pharmaceutics,
    Kanak Manjari Institute of Pharmaceutical Sciences,
    Rourkela, Odisha
    ashakeshri@yahoo.co.in

    ABSTRACT
    Hypertension or high blood pressure is a chronic medical condition in which the arterial blood pressure is elevated (normal blood pressure is 120/80 mm Hg). High Blood Pressure may lead to heart failure, stroke, coronary heart disease, kidney failure etc and may affect lungs, brain and heart. It is an important global problem and a very good percentage of people all over the world are affected by blood pressure. As there is no definite cure for this condition, hence controlling it is a big challenge. The main focus on BP management is to lower the elevated blood pressure and to prevent or reduce target organ damage. Although various antihypertensive drugs are available, they are usually associated with many sides –effects. The following article deals with the alternative measures used for lowering high blood pressure giving more importance on the various herbal drugs to be used as combination therapy.

  • 13 October 2014
    AN OVERVIEW ON MANGIFERA INDICA: IMPORTANCE AND ITS VARIOUS PHARMACOLOGICAL ACTION

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    About Author:
    Pallab Kalita
    Assam Down Town University,
    Institute of Pharmacy, Guwahati, Assam, India
    kalitapallab@gmail.com

    Abstract
    Majority of crude drugs from plant origin are used in  Indian system of medicine. Medicinal  plants are using as herbal remedies to prevent and cure several ailments differs from community to community. Most studies on the exploitation of mango have been dealing with mango peels, juices and stem bark and mango leaves. Mangifera indica (Anacardiaceae), reported to contain active substances like mangiferin. In ayurveda, one of its uses is clearing digestion and acidity. Mangiferin is a pharmacologically active flavonoids, which having the anti bacterial, antioxidant, anticancer, antidiabetes, hepatoprotective, anti inflammatory activities.

  • 10 October 2014
    ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES OF DIFFERENT TRIAZOLE ANALOGUES

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    ABOUT AUTHOR
    Mohammad Asif
    Department of Pharmacy, GRD(PG) Institute of Management and Technology,
    Dehradun, Uttarakhand, India
    aasif321@gmail.com

    ABSTRACT
    Different heterocyclic analogues were evaluated for their diverse biological activities. The triazole moiety seems to be very small but in the biological profile has attracted the attention of many researchers to explore this skeleton to its multiple potential against several activities. Triazole analogues have a wide range of biological applications including antimicrobial, antimalarial, antitubercular, anti-inflammatory, analgesic, antiepileptic, antiviral, antihypertensive, antianxiety, antidepressant, antihistaminic activities etc. This review provides a brief response of the medicinal chemistry of triazole analogues particulary as analgesic and anti-inflammatory activities.

  • 6 October 2014
    DR.SUBHAS MUKHERJEE AND INDIA’S FIRST TEST TUBE BABY

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    ABOUT AUTHOR:
    Avlikant J. Dhawale*
    RedCross Formulation, Ajanta Pharma, Aurangabad, Maharashtra
    Department of Biochemistry, Gramin Science College (Swami Ramanand Tirth Marathwada University), Nanded, Maharashtra, India
    *dhawale111@gmail.com

    ABSTRACT:
    Infertility is the inability of an animal or plant to reproduce by natural means. Many people in the world are facing the problem of infertility altimatlely the problem of saving their generations. Today, modern science chalanged and solved the problem of infertility by developing the technique of Test Tube Baby by using principle of in-vitro fertilization.

    Dr. Subhas Mukherjee, first Asian who invented most easy and successful method of producing Test Tube Baby. In Culcutta, West Bengal, on 3rd October 1978, the team announced the birth of World's Second Test Tube baby named as 'Durga' (Kanupriya Agarwal). The announcement came 67 days after the birth of World's First Test Tube Baby named as 'Louise Brown in England by Physiologist Robert G. Edwards who awarded the Nobel Prize for such work in 2010. During his lifetime, Government of West Bengal didn't recognized his work. By the day to day insult from government Dr. Subhas Mukherjee committed to suicide.

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