Madhya Pradesh

A REVIEW: PLANTS AND HERBS USED IN ANXIETY

About Authors:
Awan Bharti*1, Sweta Gautam2
1Department of Pharmacognosy,
Shri Rawatpura Sarkar Institute of Pharmacy, Datia, M.P.
2Department of Pharmacognosy, RKDF College of Pharmacy, Bhopal
*bhartiawan@gmail.com, shwetagautam85@rediffmail

ABSTRACT
Interest in alternative medicine and plant-derived medications that affect the "mind" is growing. Anxiety affects one-eighth of the total population of the world and has become a very important area of research interest in psychopharmacology during this decade. Anxiety, a state of excessive fear, is characterized by motor tension, sympathetic hyperactivity, and apprehension and vigilance syndromes. Benzodiazepines are the major class of compounds used in anxiety and they have remained the most commonly prescribed treatment for anxiety, despite the important unwanted side effects that they produce such as sedation, muscle relaxation, ataxia, amnesia, ethanol and barbiturate potentiation and tolerance. Various types of herbal medicines have been used as anxiolytic drugs in different parts of the world. Folk medicines have particular values, for example, plants that "calm down", tranquilize, and raise mood, such as Passiflora coerulea, Valeriana officinalis, Matricaria recutita, Jatropa cilliata, Salvia guaranitica, Tilia tormentosa, and Tilia europeae. Plants have long been used to treat central nervous system (CNS) disorders.

A REVIEW ARTICLE ON ANTIFUNGAL AND ANTIMICROBIAL ACTIVITY OF TAGETES ERECTA

About Author:
Bandana patel
Shri Ram Institute Of Technology
Jabalpur(M.P.) 482002
Vandanapatel.mbbs@gmail.com

Abstract:
Tagetes erectus
leaf  were evaluated against various gram +ve and gram–ve bacteria and fungi, ethanol extracts exhibited very satisfactory inhibitory activity. Further studies involving the isolation, characterization and purification of the chemical compounds of the plant and screening for antibacterial and antifungal may result in the development of a potent entity which will be of lower toxicity and a high therapeutic value to the mankind.

REVIEW ARTICLE ON ANTIMICROBIAL, ANXIOLYTIC AND MUSCLE RELAXANT ACTIVITY OF ECLIPTA ALBA (BHRINGRAJ)

About Authors:
Nishtha mukherjee
Shri ram institute of technology
jabalpur (m.p.) 482002
Nishthamukherjee210@gmail.com

ABSTRACT: Eclipta alba offers a remarkable activities for curing of many diseases. It has wide range of chemical constituents. Clinical investigations have been done on pharmacological activities like hepatotoxicity, proliferative, diabetic, hypolipedemic etc. Eclipta alba leaves were collected and dried. Furthur aquous and ethanolic extract were prepared and evaluated for anti microbial, anxiolytic and muscle relaxant activity.

ALZHEIMER DISEASE AND CONTRIBUTION OF NANOTECHNOLOGY AND HERBALTRADITIONAL DRUGS IN THE TREATMENT OF ALZHEIMER DISEASE

About Authors:
Himani sharma
B.pharm; mahakal institute of pharmaceutical studies,
Ujjain (m.p.); rgpv
shimani53@gmail.com

ABSTRACT
Among the several identified types of dementia, Alzheimer's dis­ease (AD) is the most common. In 1906 a German physician, Dr. Alois Alzheimer, specifically identified a collection of brain cell abnormalities as a disease which is a degenerative brain disorder. Today, this degenerative brain disorder bears his name, and when found during an autopsy, these plaques and tangles mean a definite diagnosis of Alzheimer's disease (AD).  This article provides a general idea of some main causes ofAlzheimer's disease, use of various prospects of nanotechnology herbal medicines and intended to explain the therapeutic effectiveness of various herbal medicines in the treatment of Alzheimer disease.

A COMPREHENSIVE REVIEW ON TUMARI (TREWIA NUDIFLORA LINN.)

About Authors:
N. Balakrishnan*, Mayank Srivastava, Pallavi Tiwari
Department of Pharmacognosy,
Technocrats Institute of Technology-Pharmacy,
Bhopal-462021(MP), India.
*pharmacobala@gmail.com

Abstract
Medicinal plants have main and cheap source of unique phytoconstituents, they are used extensively in the development of new drugs against various diseases and disorders. The 80% of world population especially in the developing countries relies on the traditional system of medicine for primary choice to treat diseases. Trewia nudiflora Linnbelongs to the family Euphorbiaceae and is one of the important medicinal plant in Indian systems of medicine like Ayurveda, Siddha,etc. It is used as stomachic and alterative in flatulence, gout, rheumatism and malignancy especially leukemia and hepato- biliary affections etc.  The decoction of shoots and leaves of Trewia nudiflora is used to treat excessive bile and sputum. The leaves are applied on wounds to heal them with good efficiency. It contains a pyridine alkaloid, N-methyl-5-carboxamide-2-pyridone. Hence,an attempt has been made in this review paper to explore various phytochemical and pharmacological studies carried out on this plant.


REVIEW ARTICLE ON ANTIMICROBIAL ACTIVITY OF THESPESIA POPULNIA SEEDS

About Author:
Sharad kumar awasthi

Shri Ram Institute Of Technology,
Jabalpur (M.P.) 482002.
Sharad20n@gmail.com

ABSTRACT:
Thespesia populnia seeds were dried and then grinded to obtain fine powder. Ethanolic and aqueous extracts and etheral extract of thespesia seeds were evaluated for antibacterial activity against E.coli, B.subtilis with the comparison control (Ciprofloxacin and Amoxicillin) for bacteria. The extract showed good inhibitory activity on the microbes.

REGULATORY CONTROL ON BANNED DRUG: A REVIEW ARTICLE

About Authors:
Priya Diwedi
M.pharm, Bhopal institute of technology and science-pharmacy,
Bhopal (M.P)
Priya.diwedi07@gmail.com

ABSTRACT:
A Number of drug that are banned in abroad are freely available in the Indian market. The most pitiable feature is that use of these drugs are regularly causing long term implication for our physical health. Some of the common ones that are easily available and people use frequently without doctor’s prescription are D-cold, Nimesulide and Analgin. These are use as pain killer but latest research shows that long term use of such medicines can affect human health in various ways by damaging liver, causing irregular heartbeats, depression, blood pressure fluctuations etc. This is the prime reason that most of European countries have disqualified and banned the manufacturing and consumption of these drugs. It has been recently pointed out that Indian drug regulatory authorities have refused to ban sale of 11 drug, including Furazolidone, Phenypropanolamine, Cisapride and Nimuselide, apart from over 80 drug combinations that are prohibited in other countries IPA have made various regulation and guideline for the control of  these drug, but still they are in use because of lack of awareness in people.

PHARMACOGNOSTIC INVESTIGATION OF ELAEOCARPUS GANITRUS Roxb. LEAF AND SEED

About Authors:
Awan Bharti
Department of Pharmacognosy,
Shri Rawatpura Sarkar Institute of Pharmacy,
Datia, M.P.
bhartiawan@gmail.com

ABSTRACT
Elaeocarpus ganitrus Roxb. (Family: Elaeocarpaceae) commonly known as Rudraksha. Rudraksha beads, the holy beads scientifically called as Elaeocarpus Ganitrus. It possesses good medicinal value and with religious, medicinal and spiritual significances. Present investigation deals with macroscopic, microscopic. Microscopic studies revealed the presence of cuticle, epidermis, collenchyma, vascular bundle, xylem and phloem, hard endocarp, seeds with membranous seed coat.


EFFECT OF PRUNUS AMYGDALUS (BATSCH) IN DIFFERENT MODELS OF ULCER

About Authors:
Devendra Kumar1,Pragya Seth2
Department of Pharmaceutical technology,
1Sri Satya Sai collage of Pharmacy Bhopal,
2Lakshmi Narain College of Pharmacy, Bhopal
*guptadevendra15@gmail.com

Abstract
The present work describes the effect of methanolic extract of Prunus amygdalus (batsch.) on pylorus ligation and Ethanol-induced gastric ulcer models in Wistar rats. The present study provides a strong evidence of antiulcer activity of Prunus amygdalus extract against gastric lesions. The antiulcer activity is recognized by a reduction in acid-secretary parameters like total and free acidity, gastric volume and ulcer score suggesting that acid inhibition accelerates ulcer healing, thereby strengthening of mucosal barrier. In this present study it shows significant protection for Hexosamine in all treated groups in comparison to negative control group. Inthe LPO results it was observed that there was significance level difference in negative control group and all other group that indicates that lipid peroxides enzyme was higher in vehicle treated group. Ulcer score was determined by the counting of spots and severity of damage in stomach part by any moiety such as ethanol. Single drug treatment (200 mg/kg and 400mg/kg of P.A.E.) was effective up to a significant level (P<0.05) in compare to negative control group.Volume of gastric juice indicate the secretions of gastric fluid and it is higher in negative control group and all drug treated group was effective in relation to negative control group in significance level (P <0.05).

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