Madhya Pradesh

  • PharmaTutor
    13 March 2013

    DIFFERENT PHARMACOLOGICAL ACTIVITY OF INDIAN MEDICINAL PLANTS “ABUTILON”

    ABOUT AUTHORS:
    Girendra Kumar Gautam*1, Chandra Shekhar Singh2, S C Dwivedi3 and G Vidyasagar4
    1,3,4 Suresh Gyan Vihar University, Jaipur, Rajsthan, India
    1 Malhotra College Bhopal, Madhya Pradesh, India.
    2 Shambhunath Insitute of Pharmacy, Allahabad, Uttar Pradesh, India.
    *gk100781@gmail.com

    ABSTRACT
    From last two or three decay, there is a large growth in the sector of plant medicine means herbal medicine. It is due to increase of awareness and knowledge about plant. In India and China, the ratio of this growth is more than any other country of the world.  Interest the usage of various medicinal plants from traditional system of medicine for the treatment of different ailments is also history of India and China. Abutilon is an Indian medicinal genus which has a number of herbs specie,is noted for their medicinal benefits in traditional system of medicine. Abutilonis a large genus of approximately 150 species of broadleaf evergreens in the mallow family, Malvaceae. The genus includes annuals, perennials, shrubs, and small trees from 1–10 m tall, and is found in the tropical and subtropical regions of all continents. Some medicinally important attributes have been assigned to the plants of this species. In sort of this, the present work aim is to find out different pharmacological activity done on this Indian medicinal plant.

  • 6 March 2013
    Opportunity for Fresh B.Pharm/M.Pharm to work as Pharmacist in Big Group Hospital - 08 posts | freshers may apply

    Hospital is Very Big Group Stable in INDORE

    Post: Pharmacist - 08 posts

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    Job Responsibilities
    B Pharma , M Pharma Fresher for Chemist Profile in Hospital

  • 6 March 2013
    Applications Invited for Professors, Associate Professors, Assistant Professors in ITM UNIVERSITY

    ITM University is a multidisciplinary university known for its quality of research and teaching across the academic spectrum, with subjects spanning the sciences, engineering, management, fine arts, social sciences, arts, nursing etc.

  • 18 February 2013
    EVALUATION OF ANTIDOTE ACTIVITY OF LEAVES OF MUSA SAPIENTUM LINN. ON RATS

    About Authors:
    Vishnu Dev 1*, Rajiv saxena 2
    1 Truba Institute of pharmacy, Bhopal.
    2 Assoc. Professor, Truba Institute of pharmacy, Bhopal
    *vishnudev2007@rediffmail.com

    Abstract
    The present study was designed to investigate the anti-dote activity of the methanolic and aqueous extract of musa sapientum. The extract was evaluated by physical and serum biochemical parameters as TC and TG. Anti-dote activity of both extract was determined by acute and chronic codeine poisoning,
    Acute opioid intoxication and overdose are common causes of presentation to emergency departments. Although naloxone, a pure opioid antagonist, has been available for many years, there is still confusion over the appropriate dose and route of administration. This article looks at the reasons for this uncertainty and undertakes a literature review from which a treatment algorithm is presented.
    The anti-dote activity of musa sapientum leaves against codeine induced acute and chronic poisoning was studied in Wistar albino rats. The various fractions of the leaf extract were administered orally (200 mg/kg) simultaneously with codeine (32m g/kg) for 5-10 days. At the end of the experiment, levels of triglycerides, total cholesterol content were measured. Administration of codeine produced a CNS depressant activity and causes poisioning. There was a significant increase in total cholesterol and triglycerides when compared to normal control. physical observation indicated that simultaneous administration of the fractions delayed the onset of toxicity. All the fractions prevented the poisoning damage caused codeine overdose. The leaves of musa sapientum protected the CNS against codeine damage which may be due to its antagonist activity of codeine.

  • 1 February 2013
    A REVIEW ON: FORMULATION AND EVALUATION OF FAST DISSOLVING TABLET

    About Authors:
    Nishtha Tiwari
    Department of pharmacy,
    b.u Bhopal (m.p.), India
    Nishthatiwari.18@gmail.com

    ABSTRACT
    The oral route of drug administration is the most important method for administering drugs for systemic effects. Except in certain cases the parenteral route is not routinely used for self administration, e.g. insulin. The topical route of administration has only recently been employed to deliver drugs to the body for systemic effects. The parenteral route of administration is important in treating medical emergencies in which the subject is comatose or cannot swallow. Nevertheless it is probable that at least 90% of all drugs used to provide systemic effects are administered by the oral route.

  • 30 January 2013
    SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF SOME CALCIUM CHANNEL BLOCKER THIOSALICYLAMIDE DERIVATIVES AS ANTIHYPERTENSIVE AGENTS

    About Author:
    ABHISHAK SINGH PARMAR,
    M.PHARMACY (MEDICINAL AND PHARMACEUTICAL CHEMISTRY),
    B.R.NAHATA COLLEGE OF PHARMACY,
    MANDSAUR (M.P).
    *abhishakparmar@gmail.com

    1. INTRODUCTION
    1.1 Medicinal and Pharmaceutical chemistry
    It is a discipline at the intersection of chemistry and pharmacology involved with designing, synthesizing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use. It also includes the study of existing drugs, their biological properties, and their quantitative structure-activity relationships (QSAR). Pharmaceutical chemistry is focused on quality aspects of medicines and aims to assure fitness for the purpose of medicinal products. Compounds used as medicines are overwhelmingly organic compounds including small organic molecules and biopolymers. However, inorganic compounds and metal-containing compounds have been found to be useful as drugs. For example, the cis-platin series of platinum-containing complexes have found use as anti-cancer agents.1

  • 20 January 2013
    FORMULATION AND CHARACTERIZATION OF THEOPHYLLINE MICROSPHERE

    About Authors:
    Sofiya Verma*, Dipak V, Ashok A, Neha C, Jagruti R, Ashutosh. M
    Shri ram institute of pharmacy
    Jabalpur M.P
    *sofiyavermamph@gmail.com

    ABSTRACT:
    The purpose of this research was to prepare and characterize theophylline microsphere of guar gum polymer for the application of nocturnal asthma. The microsphere were prepared by using emulsification method using sodium borate as a cross linking agent and coating was done by solvent evaporation method with the pH sensitive eudragit S-100 polymers. The prepared microsphere were white, free flowing and spherical in shape. The drug-loaded microsphere showed entrapment efficiency and   drug release was extended upto 6 to 8 h. The infrared spectra, differential scanning calorimetry thermographs and XRD spectra all showed the stable character of both the drugs in the drug-loaded microspheres and revealed the absence of drug-polymer interactions. Scanning electron microscopy study revealed that the microspheres were spherical and porous in nature. The prepared theopylline microsphere has the potential for delaying the release of drug.

  • 14 January 2013
    Tropical Forest Research Institute invites Junior Research Fellow, Field Assistant, Project Staff | 6 Posts

    Indian Council of Forestry Research and Education (ICFRE), an apex body in the national forestry research system, has been undertaking the holistic development of forestry research through need based planning, promoting, conducting and coordinating research, education and extension covering all aspects of forestry.

  • 11 January 2013
    A MAJOR APPROACH- 2-CHLOROPYRIDINE-5-TRIFLUOROMETHYL DERIVATIVE AS ANTIAMNESIC AGENTS

    About Author:
    Ravindra Singh Tomar
    M.Pharm (Medicinal & Pharmaceutical Chemistry),
    B R Nahta College of Pharmacy, Mandsaur (M.P)
    ravindratomar16@gmail.com

    ABSTRACT-
    Here a scheme has been designed for synthesis of 2-chloropyridine-5-trifluoromethyl derivatives. The probability of being antiamnesic agent has been checked by pass prediction. All compound shows antiamnesic activity as result of pass prediction. By Lipinski rule of five all compounds shows drug like activity. Also a method for pharmacological evaluation & Biochemical evaluation is described under. All synthetic procedure has been designed & described under-

  • 10 January 2013
    THERAPEUTIC POTENTIAL AND FUTURE PROSPECT OF PSIDIUM GUAJAVA LINN

    About Author:
    Aarti Narkhede
    Mahakal Institute of Pharmaceutical Studies,
    Ujjain, MP
    narkhede_aarti@rediffmail.com

    ABSTRACT
    The use of natural product has increased tremendously in a western world as well as in developing countries or in all over part of world. via this artical therapeutic potential and future prospect of Psidium guajava L. are described. Psidium guajava L. belonging to family, myrtaceae. It is a commen tree and easily found in a tropical countries or area. Traditionally it is a very popular and used from long time in a various system of medicine like, unani, Siddha, homeopathy and Ayurveda. It is used for treatment of many ailments like diarrhea, dysentery, wounds, rheumatism, lungs problems, ulcers, skin infections, vaginal discharge, epilepsy, menstrual pain, sore throat, mouth swelling, cold and cough, toothache and etc. In present time study on antipoliferitive or anticancer activities are undertaken and it is found that anticancer activity of P.Guajava has a four time greater than vincristine.

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