Uttarakhand

A REVIEW : APPROACH IN DENTAL DRUG DELIVERY SYSTEM

ABOUT AUTHORS:
Badola Ashutosh,* Nishu Sharma
Shri Guru Ram Rai Institute of Technology & Science ( SGRRITS ),
Dehradun 248001, Uttarakhand , India
*ashutosh.badolam.pharma@gmail.com

ABSTRACT:
Controlled release local drug delivery systems offer advantages compared to systemic dosage forms for periodontitis. The objective of this research was to design and evaluate sustained release dental films containing drug in a non-biodegradable polymer for targeted delivery of the drug. The polymer ethyl cellulose was used in the formulation of dental films. The dental film was then evaluated for various parameters like thickness, folding endurance, and weight variation, and content uniformity, in vitro and in vivo study. Drug release profile of the dental film showed that the film exerted an initial burst release followed by a sustained release of the drug and the drug release was well above the minimum inhibitory concentration throughout the time of study. The release data obtained were subjected for release kinetics study. The study suggested that the non-biodegradable based dental film is a potential local drug delivery device for the treatment of periodontitis.

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NOVEL DRUG DELIVERY SYSTEM

About Authors:
Aruna Rastogi
Roorkee College of Pharmacy and UTU
Patanjali Ayurved Ltd, Sr. Chemist
arunarastogi10@gmail.com

1.   INTRODUCTION
1.1 NOVEL DRUG DELIVERY SYSTEM:
The method by which a drug is delivered can have a significant effect on its efficacy. Some drugs have an optimum concentration range within which maximum benefit is derived, and concentrations above or below this range can be toxic or produce no therapeutic benefit at all. On the other hand, the very slow progress in the efficacy of the treatment of severe diseases, has suggested a growing need for a multidisciplinary approach to the delivery of therapeutics to targets in tissues. From this, new ideas on controlling the pharmacokinetics, pharmacodynamics, non-specific toxicity, immunogenicity, biorecognition, and efficacy of drugs were generated. These new strategies, often called drug delivery systems (DDS), are based on interdisciplinary approaches that combine polymer science, pharmaceutics, bioconjugate chemistry, and molecular biology.

FORMULATION AND EVALUATION OF HERBAL CREAM

About Authors:
*1Bhuwanchandra Joshi, 2Mr.Nardev Singh
1
Division of Pharmaceutical Science, SGRRITS
2Assitant Professor
Division of Pharmaceutical Science
Shri Guru Ram Rai Institute Of Technology And Sciences,
Patel Nagar, Dehradun, Uttarakhand
*bhuwan.joshi000@gmail.com

INTRODUCTION
The cosmetics are the utility product used extensively throughout the world for maintaining and improving general appearance of face and other part of body e.g. skin, eye, hair, hand, etc. herbal cosmetics are the preparation which represent cosmetics associated with active bio-ingredients, neutraceuticals and pharmaceuticals.
Cosmetics are products that are used to cleanse and beautify the skin. The first recorded use of cosmetics is attributed to Egyptians in 4000 B.C. Pharmaceuticals are essentially drug products and are defined as products that prevent, mitigate, treat or cure disease and affect the structure or function of the body.

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