Uttarakhand

Vacancy for Medical Representative by TrueOsis Consultancy

TrueOsis ever since its inception in 2007 has been involved in providing high quality manpower solutions and services. We have been successful in providing consistent and reliable services to our customers who include BFSI, BPOs, IT Industries, Pharma, Private Manufacturing Enterprises and FMCG Companies.
The culture at TrueOsis is based on strong interaction with customers in order to provide complete satisfaction in terms of desired output.

Opening for Business Development Executive, Area Sales Manager, Sales Officer/ Territory Officer, HR Assistant, Account Assistant @ HLL Lifecare

HLL Lifecare Limited (formerly Hindustan Latex Limited) India’s leading manufacturers and marketers of Contraceptive, Health Care and Pharma products is a Mini Ratna Company under the Ministry of Health & Family Welfare, Govt. of India, with seven manufacturing units and marketing offices throughout the country.

Application are invited for Professor, Associate Professor in Kumaun University

Kumaun University is spread over in three campuses (DSB Campus, Bhimtal Campus and SS Jena Campus) with an area of 5,31,373 sq. mt. (160 acres) and built-up area of 3,00,000 sq. mt. The location of the university in Uttarakhand offers excellent research and teaching due to its landscape which is on undulating high ground. There are many herbs, shrubs and trees as well as rocks and minerals constituting eco-systems that can be studied.

NOVEL DRUG DELIVERY SYSTEM

About Authors:
Aruna Rastogi
Roorkee College of Pharmacy and UTU
Patanjali Ayurved Ltd, Sr. Chemist
arunarastogi10@gmail.com

1.   INTRODUCTION
1.1 NOVEL DRUG DELIVERY SYSTEM:
The method by which a drug is delivered can have a significant effect on its efficacy. Some drugs have an optimum concentration range within which maximum benefit is derived, and concentrations above or below this range can be toxic or produce no therapeutic benefit at all. On the other hand, the very slow progress in the efficacy of the treatment of severe diseases, has suggested a growing need for a multidisciplinary approach to the delivery of therapeutics to targets in tissues. From this, new ideas on controlling the pharmacokinetics, pharmacodynamics, non-specific toxicity, immunogenicity, biorecognition, and efficacy of drugs were generated. These new strategies, often called drug delivery systems (DDS), are based on interdisciplinary approaches that combine polymer science, pharmaceutics, bioconjugate chemistry, and molecular biology.

FORMULATION AND EVALUATION OF HERBAL CREAM

About Authors:
*1Bhuwanchandra Joshi, 2Mr.Nardev Singh
1
Division of Pharmaceutical Science, SGRRITS
2Assitant Professor
Division of Pharmaceutical Science
Shri Guru Ram Rai Institute Of Technology And Sciences,
Patel Nagar, Dehradun, Uttarakhand
*bhuwan.joshi000@gmail.com

INTRODUCTION
The cosmetics are the utility product used extensively throughout the world for maintaining and improving general appearance of face and other part of body e.g. skin, eye, hair, hand, etc. herbal cosmetics are the preparation which represent cosmetics associated with active bio-ingredients, neutraceuticals and pharmaceuticals.
Cosmetics are products that are used to cleanse and beautify the skin. The first recorded use of cosmetics is attributed to Egyptians in 4000 B.C. Pharmaceuticals are essentially drug products and are defined as products that prevent, mitigate, treat or cure disease and affect the structure or function of the body.

Job as Site Leader - Haridwar Plant in Pfizer

Founded in 1849, Pfizer is the world's premier biopharmaceutical company taking new approaches to better health. We discover, develop, manufacture and deliver quality, safe and effective prescription medicines to treat and help prevent disease for both people and animals. We also partner with healthcare providers, governments and local communities around the world to expand access to our medicines and to provide better quality health care and health system support.

A NOVEL ANTIDIABETIC DRUG: MIGLITOL: A REVIEW

About Authors:
Rahul kumar Singh
M.Pharm (Quality Assurance)
Sr. Officer Quality Assurance at Shreya Life Sciences Pvt. Ltd.,
Roorkee, Uttarakhand
rahulsingh.qa@gmail.com

Abstract
Miglitol, an oral alpha-glucosidase inhibitor, is a desoxynojirimycin derivative that delays the digestion of ingested carbohydrates, thereby resulting in a smaller rise in blood glucose concentration following meals. As a consequence of plasma glucose reduction, miglitol reduce levels of glycosylated hemoglobin in patients with Type II (non-insulin-dependent) diabetes mellitus. Systemic nonenzymatic protein glycosylation, as reflected by levels of glycosylated hemoglobin, is a function of average blood glucose concentration over time. Because its mechanism of action is different, the effect of miglitol to enhance glycemic control is additive to that of sulfonylureas when used in combination. In addition, miglitol diminishes the insulinotropic and weight-increasing effects of sulfonylureas. Miglitol has minor inhibitory activity against lactase and consequently, at the recommended doses, would not be expected to induce lactose intolerance.

DENDRIMERS FOR NOVEL DRUG DELIVERY: AN OVERVIEW

About Authors:
Roopesh Sachan
*1, Prof. Satyanand Tyagi2, Tarun Parashar1, Soniya1, Patel Chirag J*3,Patel Pinkesh3, Rishikesh Gupta4
1
*Department of Pharmaceutics, Himalayan Institute of Pharmacy and Research, Rajawala, Dehradun, Uttarakhand, India-248007.
2
President & Founder, Tyagi Pharmacy Association (TPA) & Scientific Writer (Pharmacy), Chattarpur, New Delhi, India-110074.
3
Department of Pharmaceutics, Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, Rajasthan, India-302020.
4
Institute of Pharmacy, Bundelkhand University, Jhansi, Uttar Pradesh, India-284128.
*roopeshsachan@gmail.com, +91-9557469989, 9236167104

ABSTRACT:
Nanoparticle drug-delivery systems are the popular ones as are able to increase the selectivity and stability of therapeutic agents. However reticuloendothelial system (RES) uptake, drug leakage, immunogenicity, hemolytic toxicity, cytotoxicity, hydrophobicity restrict the use of these nanostructures. These shortcomings are overcome by surface engineering the dendrimer such as Polyester dendrimer, Citric acid dendrimer, Arginine dendrimer, Glycodendrimers, PEGylated dendrimers, etc.The field of Dendrimers has recently emerged as the most commercially viable technology of this century because of its wide-ranging potential applications in many fields such as: healthcare, electronics, photonics, biotechnology, engineering products, pharmaceuticals, drug delivery, catalysis, electronic devices, environmental issues and nanotechnologies. Dendrimer as a drug delivery agent is a promising, safe and selective drug delivery option.

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