Uttarakhand

FORMULATION AND EVALUATION OF ZIDOVUDINE MICROPARTICLES USING A NOVEL BIO POLYMER FROM THE SEEDS OF BUCHANANIA LANZAN

About Authors:
Neha Tyagi*1, N.V Satheesh Madhav2
1KNGD Modi Institute Of Pharmaceutical Education And Reserach,
Modinagar-2 Uttar Pradesh, India
2Dehradun Institute Of Technology, Faculty Of Pharmacy,
Mussorie Diversion Road Village Makkawala PO Bhagwant pura -248009 Dehradun, Uttrakhand, India
*neha2487@gmail.com

Abstract:
The aim of research work was to isolate a novel bio material from the seeds of Buchanania Lanzan and to evaluate their potential for sustained drug delivery by formulating various micro particles  using  methylene chloride as solvent and bio material by solvent evaporation method. The bio polymer was isolated from the seeds of Buchanania Lanzan by simplified economical method. Four formulations were prepared using bio polymer in different ratios by solvent evaporation method. Acute toxicity studies were done in rats according to OECD guidelines. The formulated micro particles were subjected to various evaluation parameters like particle size , particle shape, entrappement efficacy and invitro drug release studies .on the basis of invitro drug release studies, the formulation with increased amount of bio polymer (FM4) was found to be better than other formulations and it was selected as optimized formulation. Invitro studies revealed that FM4 followed perfect zero first order kinetics release. among the different formulation FM4 showed release of drug for 8 hrs with  88.46%  release.

Career in Indian Medicines Pharmaceutical Corporation Ltd. - GOVERNMENT OF INDIA ENTERPRISE | 9 Posts - Requirements in Production, Quality Analysis, Materials, Medical Representative

The Company (Manufacturing Ayurvedic and Unani Medicines) having obtained drug licence from licensing authority (G.M.P. Certificate  renewed upto 09.06.2015) (Drug licence renewed upto 31.12.2010, applied for renewal) is a GOVERNMENT OF INDIA ENTERPRISE (under the Administrative Control of the Department of AYUSH (Ministry of Health & Family Welfare), Indian Red Cross Building, Red Cross Road, New Delhi).

Requirement of M. S. (Pharm.)/ M. Pharm./ M. Tech. for the post of Jr Research Fellow in UTU

Applications are invited from young and meritorious Indian citizens for filling up one position of JRF funded by the Department of Biotechnology (DBT), Govt. of India. The current project ongoing draw from recent high throughput-drug discovery campaigns, “Antifolate hit-to-lead optimization for PfDHFR-TS inhibition”.

Applications are invited for Junior Research Fellow, Senior Research Fellow, PDF in GBPUAT | Walk in

Applications are invited for the posts of Junior Research Fellow (JRF) , Senior Research Fellow (SRF) and PDF (Contractual Scientist ) in the Institute of Biotechnology , G.B. Pant University of Ag. & Tech., Patwadangar (Nainital) , Uttarakhand . The monthly emoluments and qualifications for the above posts are as follows:

A REVIEW : APPROACH IN DENTAL DRUG DELIVERY SYSTEM

ABOUT AUTHORS:
Badola Ashutosh,* Nishu Sharma
Shri Guru Ram Rai Institute of Technology & Science ( SGRRITS ),
Dehradun 248001, Uttarakhand , India
*ashutosh.badolam.pharma@gmail.com

ABSTRACT:
Controlled release local drug delivery systems offer advantages compared to systemic dosage forms for periodontitis. The objective of this research was to design and evaluate sustained release dental films containing drug in a non-biodegradable polymer for targeted delivery of the drug. The polymer ethyl cellulose was used in the formulation of dental films. The dental film was then evaluated for various parameters like thickness, folding endurance, and weight variation, and content uniformity, in vitro and in vivo study. Drug release profile of the dental film showed that the film exerted an initial burst release followed by a sustained release of the drug and the drug release was well above the minimum inhibitory concentration throughout the time of study. The release data obtained were subjected for release kinetics study. The study suggested that the non-biodegradable based dental film is a potential local drug delivery device for the treatment of periodontitis.

Applications are invited from B.Pharm, M.Sc, Ph.D for the posts of PDF, SRF and JRF in the Institute of Biotechnology , G.B. Pant University

G.B. Pant Institute of Himalayan Environment and Development (GBPIHED) was established in 1988-89, during the birth centenary year of Bharat Ratna Pt. Govind Ballabh Pant, as an autonomous Institute of the Ministry of Environment and Forests (MoEF), Govt.

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