Andhra Pradesh

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Regulatory Affairs Courses
  • 1 October 2012

    EFFECT OF ETHANOLIC EXTRACT OF ISAPGOL AGAINST DIET INDUCED UROLITHIASIS IN RATS.

    About Authors:
    *SOUMYA G., SRINIVAS S., NAVEEN KUMAR M., KRISHNA MOHAN C.
    Department of Pharmacology,
    St. John College of Pharmacy, Warangal,
    Andhra Pradesh, India-5067371.
    *sre_varma123@yahoo.co.in

    Introducion:
    Kidney stone formation or urolithiasis is a complex process that is a consequence of an imbalance between promoters and inhibitors in the kidneys. Even though the technological developments in the present medical practice the formation and growth of renal calculi continues to afflict humankind. Though various kinds of stone have been identified, calcium stones are the most common in human as well as rats. The rat experimental models of Calcium oxalate urolithiasis, induced by ethylene glycol alone, or in combination with other drugs such as ammonium chloride are often used to study the pathogenesis of kidney crystal deposition. The urolithiasis was induced by administration of gentamycin and calculi producing diet (5% ammonium oxalate in standard rat pellet feed) for 28 days to rats’ results in hyperoxaluria, Calcium oxalate crystalluria, and occasional deposition of CaOx crystals in the kidney.

  • 26 September 2012
    Opportunity for Trainee in GVK Biosciences- 15 Posts

    bioCampus, GVK Biosciences is leading Informatics Services provider with wide range of Products and Services across the R&D value chain.

  • 26 September 2012
    Career for Drug Regulatory Affairs Business Franchise/Regulatory Coordinator (RC) in Novartis

    A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

  • 25 September 2012
    Work as Medical Editor in Sanjeevani Life Sciences- 3 Posts

    Sanjeevani Life Sciences aims to be the best and foremost contract research organization committed to serve the pharmaceutical industry worldwide with high quality standards, at par with the international regulatory and professional expectations.

  • 20 September 2012
    RAJIV GANDHI UNIVERSITY OF KNOWLEDGE TECHNOLOGIES invites Pharmasists- 6 Posts

    The Government of Andhra Pradesh has established Rajiv Gandhi University of Knowledge Technologies (RGUKT) in 2008 to cater to the educational needs of the meritorious rural youth of Andhra Pradesh. Three campuses of RGUKT (fully residential) were started under the University, one each at Basar (Adilabad Dt), Nuzvid (Krishna Dt), Rajiv Knowledge Valley, Idupulapaya (YSR Kadapa Dt).

  • 20 September 2012
    CHRONOPHARMACOKINETICS: THE CIRCADIAN RHYTHM OF DRUGS AND ITS IMPLICATIONS

    About Authors:
    N Allamneni*, CH Ajay Babu, AVS Madhulatha, C Anusha, P Sowjanya, BV Komali, M Kalyani, Syed M
    *Department of Pharmaceutical Technology,
    Narasaraopeta Institute of Pharmaceutical Sciences,
    Narasaraopeta, Guntur, India.
    *yaswanthallamneni@gmail.com

    ABSTRACT
    Chronopharmacokinetics involves the study of temporal changes in drug absorption, distribution, metabolism and excretion with respect to time of administration. Drug Absorption, distribution, metabolism and elimination are influenced by many different physiological functions of the body, which may vary, with time of day. Thus, the pharmacokinetic parameters characterizing these different steps, conventionally considered to be constant in time, depend on the moment of drug administration. Chronokinetic studies have been reported for many drugs in an attempt to explain chronopharmacodynamic phenomena and demonstrate that the time of administration is a possible factor of variation in the kinetics of a drug. However, the time of day has to be regarded as an additional variable influencing the kinetics of a drug since many drugs are affected by time of administration and the activity or rest period of the human or animal.

  • 19 September 2012
    EVALUATION OF ANTHELMINTIC ACTIVITY OF ETHANOLIC ROOT EXTRACT OF ALLOPHYLUS SERRATUS.

    About Authors:
    A.SRILAKSHMI*, AMRUTHA R.E, N.KRISHNA SREE
    Department of Pharmacology
    P. Rami Reddy Memorial College of Pharmacy,
    Andhra Pradesh, India.
    *amrutharamapuram@gmail.com

    Abstract:
    Present study was aimed to evaluate the anthelmentic activity of ethanolic extract of Allophylus serratus against Indian earthworms Pheritima posthuma. The various concentrations of ehanolic extract of Allophylus serratus were tested for paralysis time and death time of the worms. Results revealed that all the concentrations of Allophylus serratus possess anthelmentic activity in a dose dependant manner. Potency of the test samples was found to be inversely proportional to the time taken for paralysis/death of the worms. The activities were comparable with the reference drug Albendazole(20mg/ml). Among the various concentrations of extracts 400mg/ml dose was found to possess promising anthelmentic activity in comparison to other extracts like 100mg/ml,200mg/ml. Phyto constituents of ethanolic extract of Allophylus serratus were found to be Flavonoids, Phenolic compounds,steroids,tri-terpenoids, Glycosides. The present study therefore justifies its use in the folklore remedies as an anthelmentic drug of natural origin.

  • 18 September 2012
    Job as MR in A leading top mnc pharma

    A leading top mnc pharma " requires “experienced medical representatives only” to launch their division in south region ( tamilnadu, karnataka, kerala, & andhrapradesh) at every district wise. male graduate in any discipline preferably in science. one must be dynamic,challenging & skillful, and age must not cross 26 years. candidates must have good communication skills in english & in their local regional language . candidates must show original documents at the time of interview.

  • 18 September 2012
    NEWER ANTILEPTICS- NECESSITY OF LIMITED DOSAGE

    About Authors:
    A.Prameela Rani1, V.Hema2*
    1University college of pharmaceutical sciences,
    Acharya nagarjuna University, Guntur.
    2*KVSR Siddhartha college of pharmaceutical sciences, Vijayawada.
    *hemav_pharma@rediffmail.com

    ABSTRACT:
    Epilepsy is a disorder of CNS characterized by paroxysmal cerebral dysrhytmia, manifesting as brief episodes of loss or disturbance of consciousness with or without characteristic body movements, sensory or psychiatric phenomenon.
    Some drugs such as felbamate, oxcarbazepine, gabapentin, zonisamide, topiramate and pregabalin before consumption their dose and dosage should be checked. All the drugs should be adjusted surely for their dosage especially in renal impairment patients. The present review is on serious effects due to overdosage of various newer anticonvulsants.

  • 13 September 2012
    Career opportunity for Sales Representative in Novartis India - 4 posts

    Novartis (NYSE: NVS) is a world leader in the research and development of products to protect and improve health and well-being. The company has core businesses in pharmaceuticals, vaccines, consumer health, generics, eye care and animal health.

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