Skip to main content

Andhra Pradesh

  • FORMULATION AND DESIGN OF METFORMIN HYDROCHLORIDE EXTENDED RELEASE TABLETS

    { DOWNLOAD AS PDF }

    ABOUT AUTHORS
    Goundla Uday Bhasker Goud1*, Jakkampudi Sri Venu Prakash1, Avadhanam Pranav Kumar2, Gangi Reddy Sreenivas Reddy2, Manikanta Sai Krishna2.
    1Department of Industrial Pharmacy
    2Department of Pharmaceutics
    Bharat Institute Of Technology, Mangalpally, Hyd, Telangana, India.
    gouds.uday04@gmail.com

    ABSTRACT
    Aim:
    The current paper was an attempt to design a extended release dosage form of Metformin hydrochloride using various grades of hydrophilic polymers, hydroxy propyl methyl cellulose (HPMC K4M, HPMC K15M, HPMC K100M and HPMC K200M) and MCC.
    Materials and Methods:
    Laboratory scale batches of 4 tablet formulations were prepared by wet granulation technique. Precompression parameters of the granules were evaluated prior to compression. Tablets were characterized as crushing strength, friability, weight variation, thickness, drug content or assay and evaluated for in-vitro release pattern for 12 hr using Phosphate buffer of pH 6.8 at 37 ± 0.5°C.
    Results and Discussion:
    The results obtained revealed that HPMC K100M in formulation (F3) was able to sustain the drug release for 12 h and followed the Higuchi pattern quasi-Fickian diffusion. and charged for stability testing, parameters were within the limit of acceptance. There was no chemical interaction found between the drug and excipients during Fourier Transform Infrared Spectroscopy (FTIR).
    Conclusion:
    Hence it can be concluded that formulation F3 containing HPMC K100M is suitable for development of extended release tablets of Metformin Hydrochloride.

  • Career as Research Assistant in NIPER, Hyderabad

    National Institute of Pharmaceutical Education and Research (NIPER) is the first national level institute in pharmaceutical sciences with a proclaimed objective of becoming a centre of excellence for advanced studies and research in pharmaceutical sciences. The Government of India has declared NIPER as an 'Institute of National Importance'. It is an autonomous body set up under the aegis of Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Government of India. The Institute is conceived to provide leadership in pharmaceutical sciences and related areas not only within the country, but also to the countries in South East Asia, South Asia and Africa. NIPER is a member of Association of Indian Universities and Association of Commonwealth Universities.

    NIPER, Hyderabad is an autonomous body which has been established under the aegis of the Ministry of Chemicals and Fertilizers, in the Government of India, to provide leadership in Pharmaceutical Sciences and other related areas. The Indian Institute of Chemical Technology, Hyderabad as Mentor Institute is inviting applications for the following position for NIPER, Hyderabad:

  • NATIONAL SEMINAR on Emerging trends and innovations in Pharmaceutical biotechnology September, 26th 2014 at Rishiraj College of Pharmacy

    Guided by focused vision and dedicated research and academics efforts, Rishiraj College of Pharmacy (LNCT Group of Institution) founded in the year 2004, has established its own identity in the field of Pharmaceutical sciences and technology in Indore. It has magnificent building, laboratories, enriched library and spacious playground. The UG (B.Pharm) and PG (M.Pharm-Pharmaceutics) are offered by the department, and developed the state of Art with modern scientific equipments for R&D.

  • Government Opportunity for Pharmacists in ITBPF (13 Posts)

    Applications are invited from Indian citizens, for filling up the vacancies for Group 'B' (Non Gazetted) & Group 'C' on temporary basis likely to be permanent in the Indo- Tibetan Border Police Force. The post has all India liability and selected candidates can be posted anywhere in India and even abroad. On appointment, the candidate shall be governed by the ITBPF Act and Rules. The last date of receipt of application is 05/09/2014 for all states except for Assam, Meghalaya, Arunachal Pradesh, Mizoram, Manipur, Nagaland, Tripura, Sikkim, Ladakh Division of Jammu and Kashmir State, Lahaul & Spiti Distt. and Pangi Sub-Division of Chamba Distt of Himachal Pradesh, Andaman & Nicobar Islands and Lakshadweep, for which last date is 12/09/2014.

    Post: Assistant Sub Inspector (Pharmacist)

  • Novartis invites for the post of Clinical Publisher I

    A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

    Post: Clinical Publisher I

  • Applications are invited for Traineeship in Andhra University

    Andhra University is not just one of the oldest educational institutions in the country, but is also the first to be conceived as a residential and teaching-cum-affiliating University, mainly devoted to post-graduate teaching and research. The people of the State have an emotional attachment to the institution, since it came into being after a prolonged and collective struggle of the Telugu elite for a University in the educationally backward northern Circars and Ceded districts of the erstwhile Madras Presidency. Andhra University was constituted in the year 1926 by the Madras Act of 1926. The 86-year-old institution is fortunate to have Sir C.R. Reddy as its founder Vice-Chancellor, as the steps taken by this visionary proved to be fruitful in the long run.

    Applications are invited from eligible candidates, for the following positions (purely temporary), sponsored by the DIM, New Delhi, for advanced research & training in Bioinforniatics.

  • Opportunity to work as Assistant Drugs Controller (10 Posts) in Department of Health and Family Welfare

    Post: Assistant Drugs Controller(India)

    [adsense:336x280:8701650588]

    No.of post: 10, UR-04, OBC-01, SC-04, ST-01

  • Advanced Certificate Course in Clinical Research at PG level by Apollo Hospitals

    Apollo Hospitals
    Apollo Hospitals is the largest integrated hospital chain in Asia.  The group has always strived to deliver the highest standard of patient care and are distinctive with their global expertise, technology and skills. The testimony of their commitment to deliver outstanding services is the Joint Commission International (JCI) accreditation that has been awarded to seven of its hospitals- a first for any hospital group in Asia. The troika of service, research and academia makes the group unique.
    These comprehensive efforts are to deliver the best to humanity, the mission of Apollo.

  • Work as Mentor Clinical SAS in UKAAT Consultancy And Services

    UKAAT Consultancy And Services Pvt. Ltd. is established to facilitate the students with useful knowledge while training them to apply the same. A training initiative which offers brain mapping along with specialized technical training for all the life science, medical and pharmacy graduates is flourishing as a pioneer training initiative in assessing the aptitude of the students and guiding them to decide their subject of interest.

    Post: Mentor Clinical SAS 3

  • Work in Novartis for the post of Scientific Writing Support Specialist I

    A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

    Post: Scientific Writing Support Specialist I

Subscribe to Andhra Pradesh